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Chu Lab Publications

Chu Lab MEDLINE references
  1. Chu G, Dudley D, Bristol T: Interaction between an electromagnetic plane wave and a spherical shell. J Appl Phys 40: 2904, l969
  2. Brower R, Chu G: A phenomenological six pion amplitude. Phys Rev D7: 56, l973
  3. Chu G: Dual model and prism plot applied to pi+ p--> pi+ pi0 p . Phys Rev D8:2887, l973
  4. Chu G, Gunion J: Probing parton distribution functions in massive lepton pair production. Phys Rev Dl0: 3672, l974
  5. Chu G, Gunion J: Production of heavy leptons in proton - proton collisions and the parton model. Phys Rev Dll: 73, l975
  6. Chu G, Koplik J: Direct muon production in a multiperipheral model. Phys Letters 55B:466, l975
  7. Chu G, Koplik J: Multiperipheral model for direct muon production. Phys Rev Dll:3l34, l975
  8. Chu G, Tam K: Three dimensional imaging in the positron camera using Fourier techniques. Phys Med Biol 22: 245-265, l977
  9. Chu G: The kinetics of target cell lysis by cytotoxic T lymphocytes: a description by Poisson statistics. J Immunol l20: l26l-1267, l978
  10. Chu G, Sharp PA: SV40 DNA transfection of cells in suspension: analysis of the efficiency of transcription and translation of T antigen. Gene l3: l97-202, l98l
  11. Chu G, Sharp PA: A gene chimera of SV40 and mouse beta globin is transcribed and properly spliced. Nature 289: 378-382, l98l
  12. Naumovski L, Chu G, Berg P, Friedberg EC: The rad3 gene of S. cerevisiae: nucleotide sequence of wild type and mutant alleles, transcript mapping and aspects of gene regulation. Mol Cell Biol 5: l7-26, l985
  13. Chu G, Berg P: Rapid assay for detection of Escherichia coli xanthine-guanine phosphoribosyltransferase activity in transduced animal cells. Nuc Acids Res l3: 292l-2930, l985
  14. Chu G, Vollrath D, Davis RW: Separation of large DNA molecules by contour-clamped homogeneous electric fields. Science 234: 1582-1585, l986
  15. Chu G, Hayakawa H, Berg P: Electroporation for the efficient transfection of mammalian cells with DNA. Nuc Acids Res 15: 1311-1325, l987
  16. Chu G, Berg P: Cisplatin cross-linked DNA: a new probe for the DNA repair defect in xeroderma pigmentosum. Mol Biol Med 4: 277-290, 1987
  17. Chu G, Chang E: Xeroderma pigmentosum group E cells lack a nuclear factor that binds to damaged DNA. Science 242: 564-567, 1988
  18. Patterson M, Chu G: Evidence that xeroderma pigmentosum group E is deficient in a homolog of yeast photolyase. Mol Cell Biol 9: 5105-5112, 1989
  19. Chu G: Pulsed field electrophoresis for the resolution of DNA by size or topology. Electrophoresis 10: 290-295, 1989
  20. Chu G, Chang E: Cisplatin resistant cells express increased levels of a factor that recognizes damaged DNA. Proc Natl Acad Sci USA 87: 3324-3327, 1990
  21. Chu G, Chang E, Patterson M: How cells recognize damaged DNA: clues from xeroderma pigmentosum and yeast. Prog Clin Biol Res 340A: 275-282, 1990
  22. Chu G: Pulsed-field gel electrophoresis: theory and practice. Methods 1: 129-142, 1990
  23. Chu G: Apparatus for contour-clamped homogeneous electric fields. Methods 1: 212-214, 1990
  24. Chu G, Gunderson K: Separation of large DNA by a variable-angle contour-clamped homogeneous electric field apparatus. Anal Biochem 194: 439-446, 1991
  25. Gunderson K, Chu G: Pulsed-field electrophoresis of megabase-sized DNA. Mol Cell Biol 11: 3348-3354, 1991
  26. Chu G: Bag model for DNA migrating in a pulsed electric field. Proc Natl Acad Sci USA 88: 11071-11075, 1991
  27. Zelenetz A, Chu G, Galili N, Bangs C, Horning S, Donlon T, Cleary M, Levy R: Enhanced detection of the t(14;18) translocation in malignant lymphoma using pulsed-field gel electrophoresis. Blood 78: 1-9, 1991
  28. Hwang B, Chu G: Purification and characterization of a human protein that binds to damaged DNA. Biochemistry 32: 1657-1666, 1993
  29. Chu G, Mantin R, Shen Y-M, Baskett G, Sussman H: Massive cisplatin overdose by accidental substitution for carboplatin: toxicity and management. Cancer 72: 3707-3714, 1993
  30. Chu G: Cellular responses to cisplatin. J Biol Chem 269: 787-790, 1994
  31. Rathmell WK, Chu G: A DNA-end-binding factor involved in double-strand break repair and V(D)J recombination. Mol Cell Biol 14: 4741-4748, 1994
  32. Payne A, Chu G: Xeroderma pigmentosum group E binding factor recognizes a broad spectrum of DNA damage. Mutation Res 310: 89-102, 1994
  33. Rathmell WK, Chu G: Involvement of the Ku autoantigen in the cellular response to DNA double-strand breaks. Proc Natl Acad Sci USA 91: 7623-7627, 1994
  34. Fox M, Feldman B, Chu G: A novel role for DNA photolyase: binding to DNA damaged by drugs is associated with enhanced cytotoxicity in Saccharomyces cerevisiae. Mol Cell Biol 14: 8071-8077, 1994
  35. Smider V, Rathmell WK, Lieber M, Chu G: Restoration of X-ray resistance and V(D)J recombination in mutant cells by Ku cDNA. Science 266: 288-291, 1994
  36. Hwang BJ, Liao J, Chu G: Isolation of a cDNA encoding a UV-damaged DNA binding factor defective in xeroderma pigmentosum group E cells. Mutation Res 362: 105-117, 1996
  37. Hwang BJ, Chu G: Trichloroacetic acid precipitation by ultracentrifugation to concentrate dilute protein in viscous solution. Biotechniques 20: 982-983, 1996
  38. Errami A, Smider V, Rathmell WK, He DM, Hendrickson E, Zdzienicka M, Chu G: Ku86 defines the genetic defect and restores X-ray resistance and V(D)J recombination to complementation group 5 hamster cell mutants. Mol Cell Biol 16: 1519-1526, 1996
  39. Chu G, Mayne L: Xeroderma pigmentosum, Cockayne syndrome and trichothiodystrophy: do the genes explain the diseases? Trends Genet 12: 187-192, 1996
  40. Hwang BJ, Smith A, Chu G: Internal sequence analysis of proteins eluted from polyacrylamide gels. J. Chromatog B: Biomed Applic 686: 165-175, 1996
  41. Rathmell WK, Kaufmann WK, Hurt JC, Byrd LL, Chu G: DNA-dependent protein kinase is not required for accumulation of p53 or cell cycle arrest after DNA damage. Cancer Res 57: 68-74, 1997
  42. Chu G: Double-strand break repair. J. Biol. Chem. 272: 24097-24100, 1997
  43. Smider V, Chu G: The end-joining reaction in V(D)J recombination. Sem Immun 9: 189-197, 1997
  44. Hammarsten O, Chu G: DNA-dependent protein kinase: DNA binding and activation in the absence of Ku. Proc Natl Acad Sci USA 95: 525-530, 1998
  45. Hwang BJ, Toering S, Francke U, Chu G: p48 activates UV-damaged DNA binding factor and is mutated in xeroderma pigmentosum group E. Mol Cell Biol 18: 4391-4399, 1998
  46. Smider V, Rathmell WK, Brown G, Lewis S, Chu G: Failure of hairpin-ended and nicked DNA to activate DNA-dependent protein kinase: implications for V(D)J recombination. Mol Cell Biol 18: 6853-6858, 1998
  47. Hwang BJ, Ford J, Hanawalt PC, Chu G: Expression of the p48 xeroderma pigmentosum gene is p53-dependent and is involved in global genomic repair. Proc Natl Acad Sci USA 96: 424-428, 1999
  48. Leuther K, Hammarsten O, Kornberg R, Chu G: Structure of DNA-dependent protein kinase: implications for its regulation by DNA. EMBO J 18: 1114-1123, 1999
  49. Hammarsten O, DeFazio L, Chu G: Activation of DNA-dependent protein kinase by single-stranded DNA ends. J Biol Chem 275: 1541-1550, 2000
  50. Tang J, Hwang BJ, Ford JM, Hanawalt PC, Chu G: Xeroderma pigmentosum p48 gene enhances global genomic repair and suppresses UV-induced mutagenesis. Molecular Cell 5: 737-744, 2000
  51. Tusher V, Tibshirani R & Chu G: Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci USA 98: 5116-5121, 2001
  52. Thorstenson Y, Shen P, Tusher V, Wayne T, Davis R, Chu G, Oefner P: Global analysis of ATM polymorphism reveals a high degree of functional constraint. Am J Hum Genet 69: 396-412, 2001
  53. Chu G: Global genomic repair and p53 in a dance after DNA damage. Cancer Biol. Therapy 1: 150-151, 2002
  54. Lossos I, Thorstenson Y, Wayne T, Oefner P, Levy R, Chu G: Absence of the ATM gene is not involved in the pathogenesis of either follicle center lymphomas or its transformation to higher-grade lymphomas. Leukemia and Lymphoma 43: 1079-1085, 2002
  55. Tan T, Chu G: p53 binds and activates the xeroderma pigmentosum p48 gene in humans but not mice. Mol Cell Biol 22: 3247-3254, 2002
  56. Tibshirani R, Hastie T, Narasimhan B, Chu G: Multi-class diagnosis of cancers using shrunken centroids of gene expression. Proc Natl Acad Sci USA 99: 6567-6572, 2002
  57. DeFazio L, Stansel R, Griffith J, Chu G: Synapsis of DNA ends by the DNA-dependent protein kinase. EMBO J 21: 3192-3200, 2002
  58. Chu G: Global genomic repair and p53 in a dance after DNA damage. Cancer Biol Ther 1: 150-151, 2002
  59. Tang J, Chu G: Xeroderma pigmentosum group E and UV-damaged DNA binding protein. DNA Repair 1: 601-616, 2002
  60. Cong F, Tang J, Hwang BJ, Voung B, Chu G, Goff S: Interaction between UV-damaged DNA binding protein and the c-Abl tyrosine kinase. J Biol Chem 277:34870-34878, 2002
  61. Tibshirani R, Hastie T, Narasimhan B, Chu G: Class prediction by nearest shrunken centroids, with applications to DNA microarrays. Statistical Sci 18:104-117, 2003
  62. Thorstenson Y, Roxas A, Kroiss R, Jenkins M, Yu K, Bachrich T, Muhr D, Wayne T, Chu G, Davis R, Wagner T, Oefner P: Contributions of ATM mutations to hereditary breast and ovarian cancer. Cancer Res 63: 3325-3333, 2003
  63. Rieger K, Hong WJ, Tusher VG, Tang J, Tibshirani R, Chu G: Toxicity from radiation therapy associated with abnormal transcriptional responses to DNA damage. Proc Natl Acad Sci USA 101: 6635-6640, 2004
  64. Rieger K, Chu G: Portrait of transcriptional responses to ultraviolet and ionizing radiation in human cells. Nuc Acids Res 32(16): 4786-4803, 2004
  65. Budman J, Chu G: Processing of DNA for nonhomologous end-joining by cell-free extract. EMBO J 24: 849-60, 2005
  66. Sugasawa K, Okuda Y, Saijo M, Nishi R, Matsuda N, Chu G, Mori T, Iwai S, Tanaka K, Tanaka K, Hanaoka F: UV-induced ubiquitylation of XPC protein mediated by UV-DDB-ubiquitin ligase complex. Cell 121: 387-400, 2005
  67. Hong WJ, Warnke R, Chu G: Immune Signatures in Follicular Lymphoma (Corres). N Engl J Med. 352: 1496-1497, 2005. More Information.
  68. Budman J, Chu G: Assays for nonhomologous end-joining in extracts. Methods Enzymol 408: 430-444, 2006
  69. Smider V, Hwang BJ, Chu G: Electrophoretic mobility shift assays to study protein binding to damaged DNA. Methods Mol Biol 314: 323-344, 2006
  70. Budman J, Kim S, Chu G: Kinase activation and XRCC4/Ligase4 control the processing of DNA ends for nonhomologous end-joining. J Biol Chem 282: 11950-11959, 2007
  71. Tsai C, Kim S, Chu G: Cernunnos/XLF promotes ligation of mismatched and non-cohesive DNA ends. Proc Natl Acad Sci USA 104: 7851-7856, 2007

 

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