Homework Assignments
1) Select a protein from OMIM concerning the disease of interest to you.2) Search your protein for motifs with the MyHits Motif Scan Query. Be sure to Include Protsite Patterns, Prosite Frequent Patterns, Prosite Profiles, Prefiles, Pfam HMMSs (local Models) in your search. Please send me the MyHits you think are significant and at least 1 or 2 hits which you think are not statistically or biologicially significant.
3) Search your protein for blocks using the InterPro and the BLOCKS database. Please send me the InterPro domains and BLOCKS hits you think are significant and at least 1 or 2 hits which you think are not statistically or biologicially significant.
4) Search your protein for homology using the BLAST method.
Please send me a few BLAST hits you think are significant and at least 1 or 2 hits which you think are not statistically nor biologicially significant.
SwissProt Protein Sequence database
National Center for Biotechnology Information
