Ueda, H., S. Sonoda, J.L. Brown, M.P. Scott, and C. Wu (1990) A sequence-specific DNA-binding protein that activates fushi tarazu segmentation gene expression. Genes and Development 4: 624-635.
Reuter, R. and M.P. Scott (1990) Expression and functions of the homeotic genes Antennapedia and Sex combs reduced in the embryonic midgut of Drosophila. Development 109: 289-303.
Bermingham, J.R., A. Martinez-Arias, M. G. Petitt, and M.P. Scott (1990) Different patterns of transcription from the two Antennapedia promoters during Drosophila embryogenesis. Development 109: 553-566.
Reuter, R., G.E.F. Panganiban, F.M. Hoffmann , and M.P. Scott (1990) Homeotic genes regulate the spatial expression of putative growth factors in the visceral mesoderm of Drosophila embryos. Development 110:,1031-1040.
Panganiban, G.E.F., R. Reuter, M.P. Scott, and F.M. Hoffmann (1990) A Drosophila growth factor homolog, decapentaplegic, regulates homeotic gene expression within and across germ layers during midgut morphogenesis. Development 110:,1041-1050.
Hayashi, S. and M.P. Scott (1990) What determines the specificity of action of Drosophila homeodomain proteins? Cell 63: 883-894.
Tamkun, J.W., R.A. Kahn, M. Kissinger, B.J. Brizuela, C. Rulka, M.P. Scott, and J.A. Kennison (1991) The arflike gene encodes an essential GTP-binding protein in Drosophila. Proc. Nat. Acad. Sci. U.S.A.88: 3120-3124.
Brown, J.L., S. Sonoda, H. Ueda, M.P. Scott, and C. Wu (1991) Repression of fushi tarazu (ftz) segmentation gene. EMBO J.10: 665-674.
Doe, C.Q., Q. Chu-LaGraff, D.M. Wright, and M.P. Scott (1991) The prospero gene specifies cell fates in the Drosophila central nervous system. Cell 65: 451-464.
Tamkun, J.W., R. Deuring, M.P. Scott, M. Kissinger, A.M. Pattatucci, T.C. Kaufman, and J.A. Kennison (1992) brahma: A transregulator of Drosophila homeotic genes structurally related to the yeast transcriptional activator SNF2/SWI2. Cell 68: 561-572.
Andrew, D.J. and M.P. Scott (1992) Downstream of the homeotic genes. New Biologist 4: 5-15.
Oh, S.-K., M.P. Scott, and P. Sarnow (1992) Homeotic gene Antennapedia mRNA contains 5'-noncoding sequences that confer translational initiation by internal ribosome binding. Genes and Development 6: 1643-1653.
Hooper, J.E., M. Pérez-Alonso, J.R. Bermingham, M. Prout, B.A. Rocklein, M. Wagenbach, J.-E. Edstrom, R. De Frutos, and M.P. Scott (1992) Comparative studies of Drosophila Antennapedia genes. Genetics 132: 453-469.
Petitt, M.G. and M.P. Scott (1992) Gene control systems affecting insect development. (Eds. J.M. Crampton and P. Eggleston). in Insect Molecular Science, 16th Symp. Roy. Entomol. Soc., Academic Press, London.
Hooper, J.E. and M.P. Scott (1992) The molecular genetic basis of positional information in insect segments. In: Early Embryonic Development of Animals, volume 18 of "Results and Problems in Cell Differentiation", pp.1-48. W. Hennig, Ed. Springer-Verlag, Berlin.
Crabtree, G.R., U. Schibler, and M.P. Scott (1992) Transcriptional regulatory mechanisms in liver and midgut morphogenesis of vertebrates and invertebrates. In: Transcriptional Regulation (S.L. McKnight and K. R. Yamamoto, Eds.) Cold Spring Harbor Press, Cold Spring Harbor, N.Y., pp1063-1102
Manak, J.R. and M.P. Scott (1993) Able assistants for homeodomain proteins. Current Biology 3:318-320..
Scott, M.P. (1993) A rational nomenclature for vertebrate homeobox (HOX) genes. Nucleic Acids Research 21: 1687-1688.
Zeng, W., D.J. Andrew, L.D. Mathies, M.A. Horner, and M.P. Scott (1993) Ectopic expression and function of the Antp and Scr homeotic genes: The N terminus of the homeodomain is critical to functional specificity. Development 118: 339-352..
Andrew, D.J., M.A. Horner, M.G. Petitt, Sarah M. Smolik, and M.P. Scott (1994) Setting limits on homeotic gene function: Restraint of Sex combs reduced Activity by teashirt and other homeotic genes. EMBO J.13: 1132-1144.
Peterson, C.L., A. Dingwall, and M.P. Scott (1994) Five SWI/SNF gene products are components of a large multi-subunit complex required for transcriptional enhancement. Proc. Nat. Acad. Sci. U.S.A.91: 2905-2908.
Schuske, K., J.E. Hooper, and M.P. Scott (1994) patched overexpression causes loss of wingless expression in Drosophila embryos. Dev. Biol.. 164: 300-311.
Mathies, L.D., S. Kerridge, and M.P. Scott (1994) Role of the teashirt gene in Drosophila midgut morphogenesis: Secreted proteins mediate the action of homeotic genes. Development 120: 2799-2809.
Andrew, D.J. and M.P. Scott (1994) Immunological methods to map protein distributions on polytene chromosomes. In Drosophila melanogaster: Practical Uses in Cell and Molecular Biology. L.S.B. Goldstein and E. Fyrberg, Eds., pp. 353-370, Academic Press.
Manak, J.R., L.D. Mathies, and M.P. Scott (1994) Regulation of a decapentaplegic enhancer by homeotic proteins. Development 120: 3605-3619.
Scott, M.P. (1994) Intimations of a creature. Cell 79: 1121-1124.
Manak, J.R. and M.P. Scott (1994) A class act: Conservation of homeodomain protein functions. In: The Evolution of Development Mechanisms. Development Suppl. 1994, pp. 61-77.
Dingwall, A.K., S.J. Beek, C.M. McCallum, J.W. Tamkun, G.V. Kalpana, S.P. Goff, and M.P. Scott (1995) The Drosophila snr1 and brm proteins are related to yeast SWI/SNF proteins and are components of a large protein complex. Mol. Biol. Cell. 6: 777-791.
McCormick, A., N. Coré, S. Kerridge, and M.P. Scott (1995) Homeotic response elements are tightly linked to tissue-specific elements in a transcriptional enhancer of the teashirt gene. Development 121: 2799-2812.
Saenz-Robles, M.T., F. Maschat, T. Tabata, M.P. Scott, and T.B. Kornberg (1995) Selection and characterization of sequences with high affinity for the engrailed protein of Drosophila. Mech. Devel. 53: 185-195.
Bilder, D. and M.P. Scott (1995) Genomic regions required for morphogenesis of the Drosophila embryonic midgut. Genetics 141: 1087-1100.
Johnson, R.L., J. K. Grenier, and M.P. Scott (1995) patched overexpression alters wing disc size and pattern: Transcriptional and post-transcriptional effects on hedgehog targets. Development 121: 4161-4170.
Goodrich, L.V., R.L. Johnson, L. Milenkovic, J.A. McMahon, and M.P. Scott (1996) Conservation of the hedgehog/patched signaling pathway from flies to mice: Induction of a mouse patched gene by hedgehog. Genes Dev. 10: 301-312.
Marigo, V., M.P. Scott, E. Laufer, L.V. Goodrich, R.L. Johnson, and C. Tabin (1996) Conservation in hedgehog signaling: Sonic hedgehog controls the expression of a chicken patched homolog in the developing limb. Development 122: 1225-1233.
Johnson, R.L., A.L. Rothman, J. Xie, L.V. Goodrich, J.W. Bare, J.M. Bonifas, A.G. Quinn, R.M. Myers, D.R. Cox, E.H. Epstein, Jr., and M.P. Scott (1996) Human homolog of patched , a candidate gene for the basal cell nevus syndrome. Science 272: 1668-1671.
Concordet, J-P., K.E. Lewis, J.W. Moore, L. V. Goodrich, R. L. Johnson, M. P. Scott and P. W. Ingham (1996) Spatial regulation of a zebrafish patched homologue reflects the roles of sonic hedgehog and protein kinase A in neural tube and somite patterning. Development 122: 2835-2846.
Epstein, D.J., E. Marti, M.P. Scott, and A.P. McMahon (1996) Antagonizing cAMP-dependent protein kinase A in tbe dorsal CNS activates a conserved Sonic hedgehog signaling pathway. Development 122: 2885-2894.
Stone, D.M., M. Hynes, M. Armanini, T.A. Swanson, Q. Gu, R.L. Johnson, M.P. Scott, D. Pennica, A. Goddard, H. Phillips, M. Noll, J.E. Hooper, F. de Sauvage, and A. Rosenthal (1996) The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog. Nature 384: 129-134.
Scott, M.P. (1997) Hox genes, Arms and the Man. Nature Genetics 15: 117-118.
Sharkey, M., Y. Graba, and M.P. Scott (1997) Hox genes in evolution: Protein surfaces and paralog groups. Trends in Genetics 13: 145-151.
Oro, A.E., K.M. Higgins, Z. Hu, J.M. Bonifas, E. H. Epstein, Jr., and M.P. Scott (1997) Basal cell carcinomas in mice overexpressing Sonic Hedgehog. Science 276: 817-821.
Kornberg, T. and M.P. Scott (1997) Regulation of Drosophila development by transcription factors and cell-cell signaling in Exploring Genetic Mechanisms. P. Berg and M. Singer, Eds. University Science Books, Sausalito, California.
Xie, J., R.L. Johnson, X. Zhang, J.W. Bare, F.M. Waldman, P.H. Cogen, A.G. Menon, M.P. Scott, and E.H. Epstein, Jr. (1997) The PATCHED gene in several types of sporadic extracutaneous tumors. Cancer Research 57: 2369-2372.
Fan, H., A.E. Oro, M.P. Scott, and P.A. Khavari (1997) Induction of basal cell carcinoma features in transgenic human skin expressing Sonic hedgehog. Nature Medicine 3: 788-792.
Sisson, J.C., K.S. Ho, K. Suyama, and M.P. Scott (1997) Costal2, a novel kinesin-related protein in the Hedgehog/patched signaling pathway. Cell 90: 235-245.
Goodrich, L.V., L. Milenkovic, K.M. Higgins, and M. P. Scott (1997) Altered neural cell fates and medulloblastoma in mouse patched mutants. Science 277: 1109-1113.
Johnson, R.L. and M.P. Scott (1997) Control of cell growth and fate by patched genes. Cold Spring Harbor Symp. Quant. Biol. 62: 205-215.
Scott, M.P. (1997) A common language (meeting summary). Cold Spring Harbor Symp. Quant. Biol. 62: 555-562.
Coré, N., A. McCormick, C. Vola, L. Fasano, M.P. Scott, and S. Kerridge (1997) Initiation of embryonic transcription of the Drosophila homeotic gene teashirt requires fushi tarazu gene activity. Mech. Devel. 68:157-72.
Bilder, D., Y. Graba, and M.P. Scott (1997) Wnt and TGFb signals subdivide the AbdA Hox domain during mesoderm patterning. Development 125: 1781-1790.
Aszterbaum, M., A. Rothman, R.L. Johnson, M. Fisher, J. Xie, J.M. Bonifas, X. Zhang, M.P. Scott, and E.H. Epstein, Jr. (1997) Ultraviolet and ionizing radiation enhance the growth of BCCs and trichoblastomas in patched heterozygous knockout mice. J. Investigative Dermatol. 110: 885-888.
Johnson, R.L. and M.P. Scott (1998) Hedgehog signaling: New players and perplexities join the pathway. Curr. Opin. Genet. Devel. 8: 450-456.
Bilder, D. and M.P. Scott (1998) Hedgehog and Wingless induce metameric pattern in the Drosophila visceral mesoderm. Devel. Biol. 201: 43-56.
Pennacchio, L.A., D.M. Bouley, K.M. Higgins, M.P. Scott, J.L. Noebels, and R.M. Myers (1998) Progressive ataxia, myoclonic epilepsy, and cerebellar apoptosis in cystatin B-deficient mice. Nature Genetics 20: 251-258.
Oro, A.E. and M.P. Scott (1998) Splitting hairs: Dissecting roles of signaling systems in epidermal development. Cell 95: 575-578.
Weiss, J.B., T. von Ohlen, D. Mellerick, G. Dressler, C.Q. Doe, and M.P. Scott (1998) Dorsal-ventral patterning in the Drosophila central nervous system: The intermediate neuroblast defective homeobox gene specifies intermediate column identity. Genes Dev. 12: 3591-3602.
Goodrich, L.V. and M.P. Scott (1998) Hedgehog and Patched in neural development and disease. Neuron 21: 1243-1257.
Scott, M.P. (1998) Hedgehog/patched signaling in animal development and disease in Accomplishments in Cancer Research 1997, pp. 120-124. Eds. S.A. Wells and P.A. Sharp. Lippincott, Williams & Williams.
Wechsler-Reya, R.J.and M.P. Scott (1999) Control of neuronal precursor proliferation in the cerebellum by Sonic hedgehog. Neuron 22: 103-114.
Keys, D.N., D.L. Lewis, J.E. Selegue, B.J. Pearson, L.V. Goodrich, R.L. Johnson, J. Gates, M.P. Scott, and S.B. Carroll (1999) Evolution of novelty: recruitment of a hedgehog regulatory circuit in butterfly eyespot evolution. Science 283: 532-534.
Daubresse, G., R. Deuring, L. Moore, O. Papoulas, I. Zakrajsek, W.R. Waldrip, M.P. Scott, J.A. Kennison, and J.W. Tamkun (1999) The Drosophila kismet gene is related to chromatin-remodeling factors and is required for both segmentation and segment identity. Development 126: 1175-1187.
Scott, M.P. (1999) Hox proteins reach out round DNA. Nature 397: 649.
Goodrich, L.V., D. Jung, K.M. Higgins, and M.P. Scott (1999) Overexpression of ptc inhibits induction of Shh target genes and prevents normal patterning in the neural tube. Devel. Biol. 211: 323-334.
R.V. Pearse II, L.S. Collier, M.P. Scott, and C.J. Tabin (1999) Vertebrate homologues of Drosophila Suppressor of fused interact with the Gli family of transcriptional regulators. Devel. Biol., 212: 323-336.
Bailey, E., M.P. Scott, and R.L. Johnson (1999) Patched genes control signaling in animal development and tumors. Ernst Shering Research Foundation Symposium. In press.
Li, Z., C.A. Karlevitch, M.P. Fish, M.P. Scott, and R.M. Myers (1999) A putative Drosophila homolog of the Huntington disease gene. Hum. Mol. Genet. 8: 1807-1815.
Milenkovic, L., L.V. Goodrich, K.M. Higgins, and M.P. Scott (1999) Mouse patched1 controls body size determination and limb patterning. Development 126: 4431-4440.
Lewis, M.T. S. Ross, P.A. Strickland, C.W. Sugnet, M.P. Scott, and C.W. Daniel (1999) Defects in mouse mammary gland development caused by conditional haploinsufficiency of patched-1 (ptc1). Development 126: 5181-5193.
Aszterbaum, M., J. Epstein, A.E. Oro, V. Douglas, P.E. LeBoit, M.P. Scott, and E.H. Epstein Jr. (1999) Ultraviolet and ionizing radiation enhance growth of BCCs and trichoblastomas in patched heterozygote knock-out mice. Nature Medicine 5: 1285-1291.
Scott, M.P. (2000) Development: The natural history of genes. Cell 100: 27-40.
Zeng, W., K.A. Wharton, Jr., J. Mack, K. Wang, M. Gadbaw, P.S. Klein, and M.P. Scott (2000) The Drosophila naked cuticle gene encodes a novel inducible feedback antagonist of Wingless/Wnt activity. Nature 403:789-95.
Chauvet S., S. Merabet, D. Bilder, M.P. Scott, J. Pradel and Y. Graba (2000) Distinct hox protein sequences determine specificity in different tissues. Proc Natl Acad Sci USA 97:4064-4069.
Zurawel, R.H., C. Allen, R. Wechsler-Reya, M.P. Scott and C. Raffel (2000) The patched gene functions as a non-classical tumor suppressor in murine medulloblastoma. Genes, Chromosomes, & Cancer 28:77-81.
Taipale, J., M. Cooper, J. Chen, B. Wang, K. Young, R. Mann, L. Milenkovic, M.P. Scott, and P.A. Beachy (2000) Cyclopamine inhibition of Smoothened activity in the Hedgehog signaling pathway. Nature 406: 1005-1009.
Johnson, R.L., L. Milenkovic, and M.P. Scott (2000) In vivo function of the Patched protein: Requirement of the C-terminus for target gene inactivation but not Hedgehog sequestration. Molecular Cell 6: 467-478.
Furlong, E.M., D. Proffitt, and M.P. Scott (2001) Automated sorting of live transgenic embryos. Nature Biotechnology 19: 153-156.
Wechsler-Reya, R.J.and M.P. Scott (2001) The Developmental Biology of Brain Tumors. Ann. Rev. Neurosci. 24: 385-428.
Ko, D.C., M.D. Gordon, J.S. Jin, and M.P. Scott (2001) Dynamics of the NPC1 protein in the organelles of living cells. Molec. Biol. Cell 12: 601-614.
Rousset, R., J.A. Mack, K.A. Wharton, Jr., J.D. Axelrod, K.M. Cadigan, M.P. Fish, R. Nusse, and M.P. Scott (2001) Naked cuticle targets dishevelled to antagonize Wnt signal transduction. Genes Devel. 15: 658-671.
Papoulas, O., G. Daubresse, J. A. Armstrong, J. Jin, M. P. Scott, and J. W. Tamkun (2001) The HMG-domain protein BAP111 is important for the function of the BRM chromatin remodeling complex in vivo. Proc. Nat. Acad. U.S.A. 98: 5728-5733.
Wharton, Jr., K.A., G. Zimmermann, R. Rousset, E. Hick., C. J. Tabin, and M. P. Scott (2001) Vertebrate relatives of the Drosophila Naked cuticle protein bind Dishevelled and antagonize Wnt signaling. Dev. Biol. 234: 93-106.
Scott, M.P. (2001) Signalling and endocytosis: Wnt breaks down on back roads. Nature Cell Biol. 3: E185-186.
Furlong, E.E.M., E. Anderson and M. P. Scott (2001) Patterns of gene transcription during Drosophila mesoderm development. Science 293: 1629-33.
Weiss, J.B., K. L. Suyama, and M. P. Scott (2001) Jelly belly: A novel LDL receptor repeat-containing signal required for mesoderm migration and differentiation. Cell 107: 387-398.
Corcoran, R. and M.P. Scott (2001) A mouse model for medulloblastoma and basal
cell nevus syndrome. J. Neurooncology 53: 307-318.
Ho, K.S. (2002) Sonic hedgehog in the nervous system: Functions, modifications,
and mechanisms. Curr. Opin. Neurobiol. 12: 57-63.
Tree, D.R.P., J.M. Shulman, R. Rousset, M.P. Scott, and J.D. Axelrod (2002)
Prickle mediates feedback amplification to generate asymmetric planar cell polarity
signaling. Cell 109: 371-381.
Monnier, V., K.S. Ho, M. Sanyal, M.P. Scott, and A. Plessis (2002) Hedgehog
signal transduction proteins: Contacts of the Fused kinase and Ci transcription
factor with the kinesin-related protein Costal2. BMC
Dev. Biol. 2:4.
Bailey, E.C., L. Milenkovic, M.P. Scott and R.L. Johnson (2002) Several PATCHED1 missense mutations display activity in patched1 deficient fibroblasts. J. Biol. Chem. 277: 33632-33640.
Arbeitman, M.N., E.E.M. Furlong, F. Imam, E. Johnson, B.H. Null, B.S. Baker, M.A. Krasnow, M.P. Scott, R.W. Davis, and K. P. White (2002) A genomic analysis of gene expression during the life cycle of Drosophila melanogaster. Science 297: 2270-2275.
Armstrong, J.A., O. Papoulas, G. Daubresse, A.S. Sperling, J.T. Lis, M.P. Scott, and J.W. Tamkun (2002) The Drosophila BRM complex facilitates global transcription by RNA polymerase. EMBO J. 21: 5245-5254.
Rousset, R., K.A. Wharton, Jr., G. Zimmermann, and M.P. Scott (2002) Zinc-dependent interaction between Dishevelled and the Wingless/Wnt antagonist Naked Cuticle. J. Biol. Chem. 277: 49019-49026.
Ko, D.C., J. Binkley, A. Sidow, and M. P. Scott (2003) The integrity of a cholesterol-binding
pocket in NPC2 is necessary for maintenance of lysosomal cholesterol levels.
Proc. Nat. Acad. U.S.A., in press.