E Glutamic Acid in proteins E Value Expectation value. The number of distinct alignments with
scores equivalent to or better than the one of interest,
that are expected to occur in a database search purely by
chance. The lower the E-value, the more significant the
score is. echo A UNIX command for displaying the contents of a variable
to the screen (i.e. echo $TERM) ed A primitive UNIX text editor electrophoresis Separation of molecules based on their net electrical
charge. Electrostatic interactions Ionic bonds that form between charged chemical groups Electrostatic surface potential The electrostatic charges on the surface of a protein.
Often indicative of functional regions of a protein. Elongation factor A protein that plays an ancillary role in the elongation
step of transcription or translation. EMACS A UNIX text editor. e-mail Electronic mail. end labeling the attachment of a radioactive or other label to one end
of a DNA or RNA molecule endogenous retrovirus an active or inactive retroviral genome integrated into a
host chromosome endonuclease an enzyme that breaks phophodiester bonds within a
nucleic acid molecule endosymbiont theory A theory that states that the mitochondria and
chloroplasts of eukaryotic cells are derived from symbiotic
prokaryotes electron density map the distribution of electron density in a crystal (x,y,z
coordinates) which is calculated from the X-ray diffraction
pattern using a Fourier transform. enhancer A DNA sequence that binds to regulatory proteins. This
binding affects the rate at which certain intervals of DNA
are transcribed and hense, it affects the rate at which
certain proteins are made (expressed). Often confused with
"promoter", but the difference is that the enhancer sequence
can be vary far away from the DNA that it regulates. environmental variables variables that are loaded in when you log into UNIX. Can
display using the comand "setenv" enzyme A protein catalyst, working to accelerate specifical
chemical reactions in the cell. EOF End of File - The character that tells the computer when
the end of a computer file has been reached. EOL End of Line - The character that tells the computer when
the end of a line of text has been reached. Different
computers use different characters. episome A plasmid that is able to integrate into the host cell's
chromosome episome transfer Transfer of some or all of a bacterial chromosome by
integration into a plasmid EST Expressed Sequence Tag. A cDNA that is sequenced. An STS
derived from a cDNA molecule. Thus, an EST is an STS that is
found in a gene, rather than in a noncoding region of DNA.
Usually short (300-500bp) single reads. They represent a
snapshot of what is expressed in a given tissue, and/or at a
given developmental stage. Ethidium bromide A type of intercalating agent that causes mutations by
inserting between adjacent base pairs in a double-stranded
molecule. Also used to visualize DNA under UV light. Euchromatin Regions of a eukaryotic chromosome that are relatively
uncondensed, throught to contain active genes. eukaryote An organism whose DNA is enclosed in a nucleus. Includes
all "higher order" life. ex A primitive UNIX text editor. Excision repair A DNA repair process that corrects various type sof DNA
damage by excising and resynthesizing a region of
polynucleotide. executable file a file of commands (usually in machine language) that can
be run on a computer. Exon In eukaryotes, genes are often broken up into alternating
regions of exons and introns. The exons contain information
that is eventually represented in the mRNA. exon-intron boundary The nucleotide sequence at the junction between an exon
and an intron. exon skipping aberrant splicing in which one or more exons are omitted
from teh spliced RNA exon theory of genes An "introns early" hypothesis that holds that introns
were formed when the first DNA genomes were constructed. Exon trapping A method, based on cloning, for identifying the positions
of exons in a DNA sequence. exonuclease An enzyme that removes nucleotides from the ends of a
nucleic acid molecule Expressed sequence tag (EST) A cDNA that is sequenced. An STS derived from a cDNA
molecule. Thus, an EST is an STS that is found in a gene,
rather than in a noncoding region of DNA. Usually short
(300-500bp) single reads. They represent a snapshot of what
is expressed in a given tissue, and/or at a given
developmental stage. External node The end of a branch in a phylogenetic tree, representing
one of the organisms or DNA sequences being studied. Extrachromosomal gene A gene in a mitochondrial or chloroplast genome extant organism An organism that is currently existing (not extinct) Extreme value distribution The probability distribution applicable to the scores of
optimal local alignments.