Held on Tuesdays from 4:00 - 5:00 p.m. in the Beckman Center, HHMI Conference Room, B200

Date:	October 7, 2008
Speaker:	Curt Scharfe
Title:	OPA1 functions and diseases
References:	Spinazzi M et al. A novel deletion in the GTPase domain of OPA1 causes defects in mitochondrial morphology and distribution, but not in function. Hum Mol Genet. 2008 Aug 4. [Epub ahead of print] Hudson G et al. Mutation of OPA1 causes dominant optic atrophy with external ophthalmoplegia, ataxia, deafness and multiple mitochondrial DNA deletions: a novel disorder of mtDNA maintenance. Brain. 2008 Feb;131(Pt 2):329-37. Epub 2007 Dec 7.
Date:	October 14, 2008
Speaker:	Joseph Shieh
Title:	Inherited epigenetic disease?
References:	Wagner KD et al. RNA induction and inheritance of epigenetic cardiac hypertrophy in the mouse. Dev Cell. 2008 Jun;14(6):962-9. Rassoulzadegan M et al. RNA-mediated non-mendelian inheritance of an epigenetic change in the mouse. Nature. 2006 May 25;441(7092):469-74.
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