Beckman Center

A Symposium
on Molecular and Genetic Medicine

Commemorating the Tenth Anniversary of the
Opening of the Beckman Center



Fairchild Auditorium
Stanford University
April 30, 1999

10th Anniversary Beckman Symposium
April 30, 1999

8:45 - 9:00 Introduction
Paul Berg
9:00 - 9:45 David Baltimore
Pathways of NF-kB Activation and Response
9:50 - 10:35 Philippa Marrack
T-Cells: Old and New Ways to Control Their Numbers
10:40 - 11:00 Break
11:00 - 11:45 Jeremy Nathans
The Frizzled Family of Wnt Receptors
11:50 - 1:10 LUNCH
1:10 - 1:20 Introduction
Lucy Shapiro
1:25 - 2:10 Stuart Schreiber
Using and Discovering Small Molecules in Chemical Genetic Research
2:15 - 3:00 Shirley Tilgham
Genomic Imprinting in Mammals
3:00 - 3:20 Break
3:20 - 4:05 Michael Brown
Why Cholesterol?
4:10 - 4:55 Robert Weinberg
Telomerase and the Mechanism of Cell Immortalization
4:55 - 5:00 Close
Paul Berg

David Baltimore
Sixth President of the California Institute of Technology. Dr. Baltimore was awarded the 1975 Nobel Prize for his pioneering research in animal viruses. That and his subsequent research on the mammalian immune system have had profound implications for understanding cancer and AIDS.
Philippa Marrack
Howard Hughes Investigator, head of the Division of Basic Immunology at the National Jewish Medical and Research Center, Denver, Colorado. Her research has been concerned with the ontogeny and immunologic specificity of T cells, particularly as they relate to the phenomenon of autoimmunity.
Jeremy Nathans
Howard Hughes Investigator in the Department of Molecular Biology and Genetics, Neuroscience, and Ophthalmology at the Johns Hopkins University. His research interests concern the genetic regulatory mechanisms that define distinct neuronal types, secreted proteins that control the growth and differentiation of neurons, and cell surface receptors that receive organizing information during nervous system development.
Stuart Schreiber
Howard Hughes Investigator, Co-Director of the Harvard Institute of Chemistry and Cell Biology at Harvard University. Dr. Schreiber has explored the power of combinatorial synthesis, molecular genetics and specially designed assays for understanding and controlling the cellular function of signaling proteins and transcriptional regulators.
Shirley Tilgham
Howard Hughes Investigator, Howard A. Prior Professor of Life Sciences in the Department of Molecular Biology at Princeton University, and Adjunct Professor of Biochemistry at the University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School. Dr. Tilgham and her laboratory are exploring two aspects of genomic imprinting: its functions in mammalian development and its transcriptional mechanism.
Michael Brown
Department of Molecular Genetics, and Director of the M.D./Ph.D. Program, University of Texas Southwestern Center at Dallas. He and his long-time colleague, Dr. Joseph L. Goldstein, shared the Nobel Prize for their discovery of the low density lipoprotein (LDL) receptor which controls the level of cholesterol in blood. More recently he and Goldstein have discovered a novel means by which sterols regulate cholesterol metabolism at the molecular, cellular an d whole body levels.
Robert Weinberg
The Daniel K. Ludwig Professor for Cancer Research in the Whitehead Institute for Biomedical Research at the Massachusetts Institute of Technology. Dr. Weinberg and his colleagues discovered the first human cancer-causing gene, the ras oncogene, and the first known tumor suppressor gene, Rb, the retinoblastoma gene. His principal research is to determine how oncogenes and tumor suppressor genes fit together in the complex circuitry that controls cell growth.

For parking information, call Transportation @ (650) 723-9362.
One-day "A" permits are available for $6 and
One-day "C" permits are available for $2 at the transportation department ONLY.


Registration and further information
Although the symposium is open and free of charge, please register with Christina Doering, Beckman Center, B062, Stanford, CA 94305-5301
Phone: (650) 723-9145 Fax: (650) 725-4951

The event marks the celebration of two anniversaries: the 10th anniversary of the opening of the Beckman Center for Molecular and Genetic Medicine and the 40th anniversary of the move of the Stanford University School of Medicine from San Francisco to the Palo Alto campus.