in Biocomputing: Informatics and Genome Projects, D. W. Smith (Ed). Academinc Press pp. 269-306
Department of
Biochemistry,and the Section
on Medical Informatics, Stanford
University School of Medicine, Stanford
California 94305-5307.
This final chapter describes early projects to simulate biological
systems using
data and knowledge available from genomic analyses and from other
sources. We
discuss the need for simulations that span multiple levels of
biological abstraction,
from the molecule to the organism to the ecosystem, and we describe
methods
that permit the modeling of biological entities at each level. We
also review recent
research results in biological simulation. We conclude with a
discussion of the state
of the field.
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