Supplemental Table 3.

Aging-regulated genes with similarity to proteins from other organisms.

Gene

Protein

Function

T01G6.10

Alcohol/ribitol dehydrogenase

carbohydrate metabolism

R05H5.2

CDC25-like tyrosine protein phosphatase

cell cycle

bir-1

survivin

cell death

cht-1

Glycosyl hydrolase

chitinase

R04B5.9

UDP-glucuronosyltransferase

decontamination

C16A3.5

NADH-ubiquinone oxidoreductase B22

energy gen.

C14F5.4

Mitochondrial tricarboxylate carrier

energy gen.

K07A12.3

F1F0-type ATP synthase subunit g

energy gen.

Y23H5A.6

alpha catenin

extracellular

C53B7.3

EGF-like repeats

extracellular

K07C11.5

Metalloproteinase inhibitor

extracellular

W10G11.5

C-type lectin

extracellular

F25E2.3

acyl-CoA thioesterase

fatty acid oxidation

C02A12.5

G-protein coupled receptor

signaling

C18B12.2

7 transmembrane receptor

signaling

C36C5.6

G-protein coupled receptor

signaling

C39H7.6

7 transmembrane receptor

signaling

F36G9.12

G-protein coupled receptor

signaling

F41D3.5

G-protein coupled receptor

signaling

ZK262.7

G-protein coupled receptor

signaling

ZK488.9

G-protein coupled receptor

signaling

C12C8.1

HSP70

heat shock

hsp16-2

HSP16-1

heat shock

T06D8.3

Phosphatidic acid phosphatase

phosphatase

F36D3.9

Cysteine protease homolog

protease

F41E6.6

cathepsin

protease

B0285.7

aminopeptidase

protease

F44C4.5

Palmitoyl-protein thioesterase

protein modification

T04A8.5

Glut. PRPP amidotransferase

purine synth.

gst-3

Glutathione S-transferase

redox

gst-2

Glutathione S-transferase

redox

T06G6.11

Thioredoxin

redox

Y55D9A.2

RNA-binding protein

RNA binding

unc-5

Immunoglobin transmembrane receptor

signaling

F16B12.7

casein kinase I

signaling

F42H10.4

LIM domain

signaling

K08D10.10

Phospholipase A2 receptor

signaling

R151.4

FMS-related protein kinase

signaling

T22E7.1

toll-like receptor

signaling

VZC374L.1

MEK kinase

signaling

ZC196.7

glutamate receptor

signaling

ZC504.4

NIK kinase

signaling

ZK1010.9

GABA transporter

signaling

ins-2

Insulin-related

signaling

C47A4.3

Protein phosphatase

signaling

Y6B3B.11

C-3 sterol dehydrogenase

sterol metabolism

B0250.9

7-dehydrocholesterol reductase

sterol metabolism

C05G6.3

Collagen

cell structure

sym-1

leucine rich repeat

cell structure

dlg-1

DLG1

cell structure

dnc-2

dynamitin

cell structure

C33D12.5

weak similarity to myosin

cell structure

inx-3

Innexin

cell structure

bgs-1

Spectrin

cell structure

W08D2.7

RNA helicase

translation

C16A3.6

Mak16p

translation

F58E1.1

Reverse transcriptase

transposon

R13D11.7

Reverse transcriptase

transposon

Y51A2C.1

Tc1

transposon

F11D11.2

Tc3

transposon

F56A6.3

Tc3

transposon

T02G5.5

Tc3

transposon

C54E10.5

Nuclear hormone receptor

transcription

F38H12.3

Nuclear hormone receptor

transcription

F57B9.2

Cdc39p

transcription

T09A5.12

Zinc finger

transcription

T16G1.8

Ground-like domain

transcription

W01B6.9

retinoblastoma-associated protein

transcription

W03B1.9

HOX transcription factor

transcription

lin-11

LIM homeodomain transcription factor

transcription

F47D12.5

zyg-11 homolog

 

F56D1.6

Calcium-binding protein

 


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