Age-related genes (p<0.001) , excluding those with higher expression levels in blood than in kidney, arranged by fold-change

Probe ID Fold change Description
206254_AT -2.652744723 epidermal growth factor (beta-urogastrone)
206054_AT -1.904549322 kininogen
214598_AT -1.689660912 claudin 8
203549_S_AT -1.683200455 lipoprotein lipase
203548_S_AT -1.630171162 lipoprotein lipase
243562_AT -1.616562515 Consensus includes gb:BE326951 /FEA=EST /DB_XREF=gi:9200727 /DB_XREF=est:hr68a03.x1 /CLONE=IMAGE:3133612 /UG=Hs.117112 ESTs
217512_AT -1.602744436 ESTs, Highly similar to 1312232A kininogen L,high MW [Homo sapiens] [H.sapiens]
207057_AT -1.558174975 solute carrier family 16 (monocarboxylic acid transporters), member 7
218772_X_AT -1.499826948 hypothetical protein FLJ10493
221590_S_AT -1.485734727 aldehyde dehydrogenase 6 family, member A1
241925_X_AT -1.467758183 Consensus includes gb:BF207870 /FEA=EST /DB_XREF=gi:11101456 /DB_XREF=est:601862578F1 /CLONE=IMAGE:4082082 /UG=Hs.219226 ESTs
207781_S_AT -1.466523612 zinc finger protein 6 (CMPX1)
215108_X_AT -1.462704002 trinucleotide repeat containing 9
214774_X_AT -1.451217743 trinucleotide repeat containing 9
205413_AT -1.451043631 chromosome 11 open reading frame 8
205773_AT -1.450802564 KIAA0940 protein
205278_AT -1.429429929 glutamate decarboxylase 1 (brain, 67kDa)
216623_X_AT -1.423082055 trinucleotide repeat containing 9
219732_AT -1.420819266 hypothetical protein FLJ20300
209340_AT -1.419606515 UDP-N-acteylglucosamine pyrophosphorylase 1
211689_S_AT -1.413846552 transmembrane protease, serine 2
209966_X_AT -1.408031393 estrogen-related receptor gamma
203543_S_AT -1.406925416 basic transcription element binding protein 1
208869_S_AT -1.39958281 GABA(A) receptor-associated protein like 1
203542_S_AT -1.372968618 basic transcription element binding protein 1
214829_AT -1.372111527 aminoadipate-semialdehyde synthase
203962_S_AT -1.37105125 nebulette
220728_AT -1.367526747 Homo sapiens cDNA FLJ13480 fis, clone PLACE1003768
205498_AT -1.367270649 growth hormone receptor
224237_AT -1.362585586 hypothetical protein PRO2372
205343_AT -1.362110032 sulfotransferase family, cytosolic, 1C, member 1
202780_AT -1.361647292 3-oxoacid CoA transferase
211600_AT -1.357890692 gb:U20489.1 /DEF=Human glomerular epithelial protein 1 (GLEPP1) mRNA, complete cds. /FEA=mRNA /GEN=GLEPP1 /PROD=glomerular epithelial protein 1 /DB_XREF=gi:885925 /FL=gb:U20489.1
209243_S_AT -1.357662231 zinc finger, imprinted 2
242775_AT -1.355645017 Consensus includes gb:BF477980 /FEA=EST /DB_XREF=gi:11548807 /DB_XREF=est:7r08f01.x1 /CLONE=IMAGE:3707280 /UG=Hs.114959 ESTs, Weakly similar to ALUC_HUMAN !!!! ALU CLASS C WARNING ENTRY !!! H.sapiens
218350_S_AT -1.355615512 geminin, DNA replication inhibitor
217680_X_AT -1.355481009 Consensus includes gb:BG151284 /FEA=EST /DB_XREF=gi:12663314 /DB_XREF=est:nai35h10.y1 /CLONE=IMAGE:4262274 /UG=Hs.322737 ESTs
221221_S_AT -1.354180406 kelch-like 3 (Drosophila)
203961_AT -1.347855699 nebulette
208848_AT -1.346062968 alcohol dehydrogenase 5 (class III), chi polypeptide
214920_AT -1.343256482 Homo sapiens cDNA FLJ11022 fis, clone PLACE1003771
211992_AT -1.330952976 protein kinase, lysine deficient 1
212229_S_AT -1.324365469 F-box only protein 21
208868_S_AT -1.324364321 GABA(A) receptor-associated protein like 1
205371_S_AT -1.324253847 dihydrolipoamide branched chain transacylase (E2 component of branched chain keto acid dehydrogenase complex; maple syrup urine disease)
202242_AT -1.321692258 transmembrane 4 superfamily member 2
218024_AT -1.320926186 brain protein 44-like
218025_S_AT -1.320219534 peroxisomal D3,D2-enoyl-CoA isomerase
216022_AT -1.313054775 Homo sapiens mRNA; cDNA DKFZp564I153 (from clone DKFZp564I153)
210833_AT -1.311570811 prostaglandin E receptor 3 (subtype EP3)
218170_AT -1.311181087 CGI-111 protein
203335_AT -1.308224828 phytanoyl-CoA hydroxylase (Refsum disease)
217127_AT -1.308099561 Consensus includes gb:AL354872 /DEF=Human DNA sequence from clone RP11-42O15 on chromosome 1. Contains ESTs, STSs, GSSs and a CpG island. Contains the CTH gene for two isoforms of cystathionase (cystathionine gamma-lyase) and a CHORD containing protein 1 (CHP1) pseudogene /FEA=mRNA_1 /DB_XREF=gi:9717070 /UG=Hs.19904 cystathionase (cystathionine gamma-lyase)
219949_AT -1.30804865 leucine-rich repeat-containing 2
213245_AT -1.306793152 Homo sapiens cDNA FLJ30781 fis, clone FEBRA2000874
212308_AT -1.304932335 cytoplasmic linker associated protein 2
235061_AT -1.302926137 Consensus includes gb:AV706522 /FEA=EST /DB_XREF=gi:10723801 /DB_XREF=est:AV706522 /CLONE=ADBDAF07 /UG=Hs.291000 ESTs, Moderately similar to ALU7_HUMAN ALU SUBFAMILY SQ SEQUENCE CONTAMINATION WARNING ENTRY H.sapiens
202975_S_AT -1.293838188 Rho-related BTB domain containing 3
202976_S_AT -1.292997961 Rho-related BTB domain containing 3
221986_S_AT -1.292955121 hypothetical protein FLJ20059
210825_S_AT -1.291994251 erythrocyte membrane protein band 7.2 (stomatin)
201689_S_AT -1.289084468 tumor protein D52
212599_AT -1.287263946 autism-related protein 1
212771_AT -1.283318571 Homo sapiens mRNA; cDNA DKFZp564A026 (from clone DKFZp564A026)
203710_AT -1.275728962 inositol 1,4,5-triphosphate receptor, type 1
203774_AT -1.274120079 5-methyltetrahydrofolate-homocysteine methyltransferase
208905_AT -1.272572543 cytochrome c
218793_S_AT -1.271707649 sex comb on midleg-like 1 (Drosophila)
213308_AT -1.270618562 SH3 and multiple ankyrin repeat domains 2
228988_AT -1.269968488 zinc finger protein 6 (CMPX1)
216173_AT -1.265796514 Homo sapiens cDNA: FLJ21707 fis, clone COL09953
226553_AT -1.261598631 transmembrane protease, serine 2
212231_AT -1.260329796 F-box only protein 21
211458_S_AT -1.257194661 GABA(A) receptors associated protein like 3
205353_S_AT -1.256345704 prostatic binding protein
212956_AT -1.252280587 KIAA0882 protein
201688_S_AT -1.250136172 tumor protein D52
217901_AT -1.247601247 Homo sapiens, clone IMAGE:4242700, mRNA
204143_S_AT -1.246951973 rTS beta protein
217506_AT -1.246385496 ESTs, Weakly similar to hypothetical protein FLJ20378 [Homo sapiens] [H.sapiens]
213353_AT -1.246046277 ATP-binding cassette, sub-family A (ABC1), member 5
205350_AT -1.242143197 cellular retinoic acid binding protein 1
228855_AT -1.241765238 nudix (nucleoside diphosphate linked moiety X)-type motif 7
206874_S_AT -1.240919346 Ste20-related serine/threonine kinase
91920_AT -1.239980859 chondroitin sulfate proteoglycan BEHAB/brevican
201007_AT -1.238778415 hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit
212445_S_AT -1.236343559 neural precursor cell expressed, developmentally down-regulated 4-like
218432_AT -1.23606015 F-box only protein 3
219429_AT -1.235111596 fatty acid hydroxylase
200848_AT -1.234497915 S-adenosylhomocysteine hydrolase-like 1
201917_S_AT -1.234434767 hypothetical protein FLJ10618
210650_S_AT -1.232991326 piccolo (presynaptic cytomatrix protein)
217988_AT -1.230928872 enhancer of invasion 10
238692_AT -1.228941294 Consensus includes gb:AL040935 /FEA=EST /DB_XREF=gi:5409879 /DB_XREF=est:DKFZp434K1715_r1 /CLONE=DKFZp434K1715 /UG=Hs.271272 ESTs, Weakly similar to hypothetical protein H.sapiens
215578_AT -1.228025271 Homo sapiens cDNA FLJ11662 fis, clone HEMBA1004629
212181_S_AT -1.224157596 nudix (nucleoside diphosphate linked moiety X)-type motif 4
212448_AT -1.222994402 neural precursor cell expressed, developmentally down-regulated 4-like
203627_AT -1.222313368 insulin-like growth factor 1 receptor
228716_AT -1.220308403 Consensus includes gb:BG494007 /FEA=EST /DB_XREF=gi:13455521 /DB_XREF=est:602542289F1 /CLONE=IMAGE:4673182 /UG=Hs.203213 ESTs
211303_X_AT -1.220247292 folate hydrolase (prostate-specific membrane antigen) 1
230008_AT -1.219975352 Consensus includes gb:AI740914 /FEA=EST /DB_XREF=gi:5109202 /DB_XREF=est:wg18c08.x1 /CLONE=IMAGE:2365454 /UG=Hs.23799 ESTs
201690_S_AT -1.21753378 tumor protein D52
201619_AT -1.217088899 peroxiredoxin 3
216189_AT -1.216698196 Homo sapiens, clone IMAGE:3344506, mRNA, partial cds
209366_X_AT -1.216511324 cytochrome b-5
228051_AT -1.214472649 Consensus includes gb:AI979261 /FEA=EST /DB_XREF=gi:5804280 /DB_XREF=est:wr72g05.x1 /CLONE=IMAGE:2493272 /UG=Hs.102720 ESTs
205776_AT -1.213954248 flavin containing monooxygenase 5
204793_AT -1.212148497 KIAA0443 gene product
201599_AT -1.208712558 ornithine aminotransferase (gyrate atrophy)
230645_AT -1.208415086 Consensus includes gb:BF110588 /FEA=EST /DB_XREF=gi:10940278 /DB_XREF=est:7n39e12.x1 /CLONE=IMAGE:3567071 /UG=Hs.150478 ESTs, Weakly similar to KIAA0987 protein H.sapiens
209916_AT -1.20554061 KIAA1630 protein
238530_AT -1.205205741 Consensus includes gb:BF695396 /FEA=EST /DB_XREF=gi:11980804 /DB_XREF=est:602083290F1 /CLONE=IMAGE:4247399 /UG=Hs.95793 ESTs
202886_S_AT -1.203831606 protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform
203859_S_AT -1.20302619 paralemmin
240519_AT -1.202290812 Consensus includes gb:AA929011 /FEA=EST /DB_XREF=gi:3078368 /DB_XREF=est:oo04c04.s1 /CLONE=IMAGE:1565190 /UG=Hs.132894 ESTs
236170_X_AT -1.200069658 Consensus includes gb:AI377423 /FEA=EST /DB_XREF=gi:4187276 /DB_XREF=est:tc35d05.x1 /CLONE=IMAGE:2066601 /UG=Hs.134071 ESTs
203039_S_AT -1.199005603 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
221543_S_AT -1.198831295 chromosome 8 open reading frame 2
210409_AT -1.197930948 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
213263_S_AT -1.195316856 mitogen-activated protein kinase kinase kinase 12
211994_AT -1.19436248 Human clone A9A2BRB5 (CAC)n/(GTG)n repeat-containing mRNA
215300_S_AT -1.193322385 flavin containing monooxygenase 5
212568_S_AT -1.193179214 dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)
202110_AT -1.192633032 cytochrome c oxidase subunit VIIb
207507_S_AT -1.191668987 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9) isoform 3
214629_X_AT -1.191640903 reticulon 4
225173_AT -1.191062525 MacGAP protein
220925_AT -1.189402736 hypothetical protein FLJ21613 similar to rat corneal wound healing related protein
65630_AT -1.187554686 Homo sapiens, Similar to RIKEN cDNA 5530601I19 gene, clone MGC:9743 IMAGE:3854028, mRNA, complete cds
210968_S_AT -1.187356159 reticulon 4
213564_X_AT -1.185844959 lactate dehydrogenase B
219204_S_AT -1.185711603 serine racemase
218637_AT -1.184593028 hypothetical protein IMPACT
200780_X_AT -1.182224808 GNAS complex locus
201030_X_AT -1.181186358 lactate dehydrogenase B
202960_S_AT -1.17837608 methylmalonyl Coenzyme A mutase
211615_S_AT -1.17707851 leucine-rich PPR-motif containing
211509_S_AT -1.172618197 reticulon 4
201978_S_AT -1.171095639 KIAA0141 gene product
227019_AT -1.170879817 Consensus includes gb:AA129774 /FEA=EST /DB_XREF=gi:1690185 /DB_XREF=est:zl16h09.s1 /CLONE=IMAGE:502145 /UG=Hs.288905 Homo sapiens cDNA FLJ13137 fis, clone NT2RP3003150
230828_AT -1.170489263 Consensus includes gb:AI379514 /FEA=EST /DB_XREF=gi:4189367 /DB_XREF=est:tc64c02.x1 /CLONE=IMAGE:2069378 /UG=Hs.114727 Homo sapiens cDNA FLJ11154 fis, clone PLACE1006932
65472_AT -1.168756023 Homo sapiens cDNA FLJ35653 fis, clone SPLEN2013690
213738_S_AT -1.16801257 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit, isoform 1, cardiac muscle
209274_S_AT -1.167624631 hypothetical protein MGC4276 similar to CG8198
221985_AT -1.167206765 hypothetical protein FLJ20059
227632_AT -1.166545315 Consensus includes gb:N74056 /FEA=EST /DB_XREF=gi:1231341 /DB_XREF=est:za58d04.s1 /CLONE=IMAGE:296743 /UG=Hs.26966 KIAA1171 protein
219288_AT -1.166422537 HT021
212175_S_AT -1.165770541 adenylate kinase 2
204182_S_AT -1.163069735 zinc finger protein 297B
201119_S_AT -1.161325345 cytochrome c oxidase subunit VIII
201100_S_AT -1.156660123 ubiquitin specific protease 9, X chromosome (fat facets-like Drosophila)
239764_AT -1.153048662 Consensus includes gb:AA702143 /FEA=EST /DB_XREF=gi:2705256 /DB_XREF=est:zi85h05.s1 /CLONE=IMAGE:447609 /UG=Hs.190365 ESTs
212073_AT -1.152401505 casein kinase 2, alpha 1 polypeptide
219036_AT -1.150751801 p10-binding protein
223194_S_AT -1.148751862 hypothetical protein FLJ22174
204149_S_AT -1.145542116 glutathione S-transferase M1
204199_AT -1.145369427 Ral guanine nucleotide exchange factor RalGPS1A
220129_AT -1.145288174 hypothetical protein FLJ20449
200708_AT -1.14491425 glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)
207709_AT -1.144142304 protein kinase, AMP-activated, alpha 2 catalytic subunit
212273_X_AT -1.143762412 GNAS complex locus
217649_AT -1.14280468 ESTs, Highly similar to zinc finger protein 216 [Homo sapiens] [H.sapiens]
201134_X_AT -1.139959563 cytochrome c oxidase subunit VIIc
210653_S_AT -1.138757969 branched chain keto acid dehydrogenase E1, beta polypeptide (maple syrup urine disease)
209064_X_AT -1.137611418 polyadenylate binding protein-interacting protein 1
229909_AT -1.137435865 Consensus includes gb:AI654238 /FEA=EST /DB_XREF=gi:4738217 /DB_XREF=est:tq89a02.x1 /CLONE=IMAGE:2215946 /UG=Hs.98969 ESTs
210236_AT -1.135410588 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
229248_AT -1.13503627 Consensus includes gb:AA020784 /FEA=EST /DB_XREF=gi:1484592 /DB_XREF=est:ze64f01.s1 /CLONE=IMAGE:363769 /UG=Hs.25223 ESTs
204178_S_AT -1.134537858 RNA binding motif protein 14
201273_S_AT -1.133136294 signal recognition particle 9kDa
215316_AT -1.133118151 Homo sapiens mRNA; cDNA DKFZp434M091 (from clone DKFZp434M091)
218716_X_AT -1.133097613 MTO1 protein
219205_AT -1.131741326 serine racemase
213307_AT -1.131469935 SH3 and multiple ankyrin repeat domains 2
204294_AT -1.131065478 aminomethyltransferase (glycine cleavage system protein T)
221531_AT -1.131013187 recombination protein REC14
209590_AT -1.130784568 bone morphogenetic protein 7 (osteogenic protein 1)
201754_AT -1.130705956 cytochrome c oxidase subunit VIc
212114_AT -1.128297097 Homo sapiens, clone MGC:17296 IMAGE:3460701, mRNA, complete cds
204367_AT -1.126981123 Sp2 transcription factor
221823_AT -1.123376789 hypothetical gene supported by AF038182; BC009203
208248_X_AT -1.122890618 amyloid beta (A4) precursor-like protein 2
202967_AT -1.122468921 glutathione S-transferase A4
208704_X_AT -1.122416794 amyloid beta (A4) precursor-like protein 2
204300_AT -1.120064761 PET112-like (yeast)
200690_AT -1.118544924 heat shock 70kDa protein 9B (mortalin-2)
242449_AT -1.112130086 Consensus includes gb:BG054682 /FEA=EST /DB_XREF=gi:12511636 /DB_XREF=est:7o46f11.x1 /CLONE=IMAGE:3577125 /UG=Hs.144763 ESTs
212121_AT -1.108405327 DKFZP564D116 protein
232047_AT -1.108078546 Consensus includes gb:AA913635 /FEA=EST /DB_XREF=gi:3053027 /DB_XREF=est:om94f01.s2 /CLONE=IMAGE:1554841 /UG=Hs.326413 Homo sapiens cDNA FLJ20812 fis, clone ADSE01316
235269_AT -1.101709796 Consensus includes gb:BE786265 /FEA=EST /DB_XREF=gi:10207463 /DB_XREF=est:601474419F1 /CLONE=IMAGE:3877253 /UG=Hs.197680 ESTs
214233_AT 1.086061876 golgi associated, gamma adaptin ear containing, ARF binding protein 2
200757_S_AT 1.090523795 calumenin
226009_AT 1.091675591 DKFZP566F084 protein
209165_AT 1.093925622 apoptosis antagonizing transcription factor
78495_AT 1.107305608 hypothetical protein DKFZp762P2111
225844_AT 1.109360529 DNA polymerase epsilon p12 subunit
217750_S_AT 1.115000533 hypothetical protein FLJ13855
208205_AT 1.116111337 protocadherin alpha 9
239332_AT 1.119141184 Consensus includes gb:AW079559 /FEA=EST /DB_XREF=gi:6034711 /DB_XREF=est:xc18f10.x1 /CLONE=IMAGE:2584651 /UG=Hs.152258 ESTs
203452_AT 1.12034557 beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
203769_S_AT 1.121150341 steroid sulfatase (microsomal), arylsulfatase C, isozyme S
218567_X_AT 1.122805511 dipeptidylpeptidase III
226035_AT 1.125175582 KIAA1203 protein
229973_AT 1.126903087 Consensus includes gb:AI827930 /FEA=EST /DB_XREF=gi:5448688 /DB_XREF=est:wf34g12.x1 /CLONE=IMAGE:2357542 /UG=Hs.101277 ESTs
202185_AT 1.127345516 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
205477_S_AT 1.13600702 alpha-1-microglobulin/bikunin precursor
213491_X_AT 1.13811761 ribophorin II
218627_AT 1.138900807 hypothetical protein FLJ11259
208923_AT 1.139946131 cytoplasmic FMR1 interacting protein 1
210704_AT 1.139987733 fasciculation and elongation protein zeta 2 (zygin II)
203878_S_AT 1.141566576 matrix metalloproteinase 11 (stromelysin 3)
204693_AT 1.144371005 CDC42 effector protein (Rho GTPase binding) 1
244876_AT 1.146593337 Consensus includes gb:BF112140 /FEA=EST /DB_XREF=gi:10941830 /DB_XREF=est:7l40g11.x1 /CLONE=IMAGE:3524156 /UG=Hs.191950 ESTs
233959_AT 1.146921579 Consensus includes gb:W26606 /FEA=EST /DB_XREF=gi:1307584 /DB_XREF=est:35e8 /UG=Hs.136141 Human DNA sequence from clone RP1-238O23 on chromosome 6. Contains part of the gene for a novel protein similar to PIGR (polymeric immunoglobulin receptor), part of
225185_AT 1.147781598 muscle RAS oncogene homolog
213399_X_AT 1.148580043 ribophorin II
225303_AT 1.151887802 Consensus includes gb:AI049973 /FEA=EST /DB_XREF=gi:3299090 /DB_XREF=est:an38g03.x1 /CLONE=IMAGE:1700980 /UG=Hs.170142 ESTs
204558_AT 1.152762332 RAD54-like (S. cerevisiae)
210988_S_AT 1.153420605 TcD37 homolog
235571_AT 1.155082902 Consensus includes gb:AW300953 /FEA=EST /DB_XREF=gi:6710630 /DB_XREF=est:xk10b12.x1 /CLONE=IMAGE:2666303 /UG=Hs.195641 ESTs
228479_AT 1.155662152 Consensus includes gb:AI094180 /FEA=EST /DB_XREF=gi:3433156 /DB_XREF=est:qa29b09.s1 /CLONE=IMAGE:1688153 /UG=Hs.15702 ESTs
230326_S_AT 1.157284643 hypothetical protein
216427_AT 1.158279318 Homo sapiens cDNA: FLJ22786 fis, clone KAIA2150
238809_AT 1.158640219 Consensus includes gb:BF439305 /FEA=EST /DB_XREF=gi:11451822 /DB_XREF=est:nab62f12.x1 /CLONE=IMAGE:3272590 /UG=Hs.154929 ESTs
230381_AT 1.158734789 Consensus includes gb:AI587638 /FEA=EST /DB_XREF=gi:4574079 /DB_XREF=est:tr80b03.x1 /CLONE=IMAGE:2224589 /UG=Hs.97258 ESTs, Moderately similar to S29539 ribosomal protein L13a, cytosolic H.sapiens
213832_AT 1.159098844 Homo sapiens clone 24405 mRNA sequence
209946_AT 1.16170491 vascular endothelial growth factor C
223626_X_AT 1.162485201 TLH29 protein precursor
210605_S_AT 1.163276135 milk fat globule-EGF factor 8 protein
207413_S_AT 1.163398138 sodium channel, voltage-gated, type V, alpha polypeptide (long (electrocardiographic) QT syndrome 3)
209506_S_AT 1.163479951 nuclear receptor subfamily 2, group F, member 1
201797_S_AT 1.165527424 valyl-tRNA synthetase 2
211587_X_AT 1.166963712 cholinergic receptor, nicotinic, alpha polypeptide 3
222688_AT 1.16706248 alkaline phytoceramidase
231496_AT 1.16918117 FKSG87 protein
211241_AT 1.169510286 annexin A2 pseudogene 3
214719_AT 1.171387212 Homo sapiens cDNA: FLJ23067 fis, clone LNG04993
218358_AT 1.173982864 hypothetical protein MGC11256
218634_AT 1.174349756 pleckstrin homology-like domain, family A, member 3
231411_AT 1.176079104 lipoma HMGIC fusion partner
202686_S_AT 1.177256183 AXL receptor tyrosine kinase
204215_AT 1.177923094 hypothetical protein MGC4175
209641_S_AT 1.180297137 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
228937_AT 1.181527084 Consensus includes gb:AI659800 /FEA=EST /DB_XREF=gi:4763370 /DB_XREF=est:tu03b01.x1 /CLONE=IMAGE:2249929 /UG=Hs.24250 ESTs
216194_S_AT 1.182566653 cytoskeleton-associated protein 1
208837_AT 1.182670307 integral type I protein
212566_AT 1.182737899 microtubule-associated protein 4
32402_S_AT 1.183160054 symplekin; Huntingtin interacting protein I
207752_X_AT 1.184738166 proline-rich protein BstNI subfamily 1
227776_AT 1.185536023 Consensus includes gb:BF589251 /FEA=EST /DB_XREF=gi:11681575 /DB_XREF=est:nab29d09.x1 /CLONE=IMAGE:3267137 /UG=Hs.27172 ESTs
202336_S_AT 1.185997937 peptidylglycine alpha-amidating monooxygenase
221739_AT 1.186943284 interleukin 27
207714_S_AT 1.189557616 serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
219768_AT 1.196282401 hypothetical protein FLJ22418
224893_AT 1.19715819 Consensus includes gb:AA775408 /FEA=EST /DB_XREF=gi:2834742 /DB_XREF=est:ad13b10.s1 /CLONE=IMAGE:878107 /UG=Hs.93659 protein disulfide isomerase related protein (calcium-binding protein, intestinal-related)
222288_AT 1.19731715 ESTs, Weakly similar to hypothetical protein FLJ20489 [Homo sapiens] [H.sapiens]
202800_AT 1.198273846 solute carrier family 1 (glial high affinity glutamate transporter), member 3
225190_X_AT 1.199233799 ribosomal protein L35a
226000_AT 1.199543769 hypothetical protein DKFZp547A023
224710_AT 1.201989922 RAB34, member RAS oncogene family
223551_AT 1.202954395 protein kinase (cAMP-dependent, catalytic) inhibitor beta
212680_X_AT 1.203327214 protein phosphatase 1, regulatory (inhibitor) subunit 14B
200654_AT 1.203766272 procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide (protein disulfide isomerase; thyroid hormone binding protein p55)
202117_AT 1.204302402 Rho GTPase activating protein 1
209574_S_AT 1.204484226 chromosome 18 open reading frame 1
201944_AT 1.206435219 hexosaminidase B (beta polypeptide)
209925_AT 1.208021557 occludin
208658_AT 1.2107325 protein disulfide isomerase related protein (calcium-binding protein, intestinal-related)
203423_AT 1.210740011 retinol binding protein 1, cellular
224928_AT 1.211727589 KIAA1717 protein
212013_AT 1.213796445 Melanoma associated gene
209869_AT 1.215037002 adrenergic, alpha-2A-, receptor
227752_AT 1.216047557 Consensus includes gb:AA005105 /FEA=EST /DB_XREF=gi:1448894 /DB_XREF=est:zh96f09.s1 /CLONE=IMAGE:429161 /UG=Hs.18441 ESTs
224531_AT 1.216607034 G protein-coupled receptor 61
206860_S_AT 1.218715307 hypothetical protein FLJ20323
204589_AT 1.220213502 KIAA0537 gene product
244602_AT 1.221077865 Consensus includes gb:AI638020 /FEA=EST /DB_XREF=gi:4690254 /DB_XREF=est:tt06b06.x1 /CLONE=IMAGE:2239955 /UG=Hs.313651 ESTs
238604_AT 1.22368523 Consensus includes gb:AA768884 /FEA=EST /DB_XREF=gi:2820122 /DB_XREF=est:nz82e07.s1 /CLONE=IMAGE:1301988 /UG=Hs.140489 ESTs
228315_AT 1.225992752 Consensus includes gb:AI632728 /FEA=EST /DB_XREF=gi:4684058 /DB_XREF=est:wa33e10.x1 /CLONE=IMAGE:2299914 /UG=Hs.25144 ESTs
218007_S_AT 1.225996491 ribosomal protein S27-like
200095_X_AT 1.226683191 ribosomal protein S10
205151_S_AT 1.226985415 KIAA0644 gene product
203954_X_AT 1.228367034 claudin 3
225102_AT 1.229843848 Consensus includes gb:BG168471 /FEA=EST /DB_XREF=gi:12675184 /DB_XREF=est:602339623F1 /CLONE=IMAGE:4447685 /UG=Hs.3964 Homo sapiens clone 24877 mRNA sequence
201792_AT 1.230026928 AE binding protein 1
226801_S_AT 1.23180185 hypothetical protein FLJ12806
201011_AT 1.231973181 ribophorin I
207134_X_AT 1.232180791 tryptase beta 2
200002_AT 1.234728973 ribosomal protein L35
208789_AT 1.235881012 polymerase I and transcript release factor
204154_AT 1.236601919 cysteine dioxygenase, type I
229256_AT 1.236980622 Consensus includes gb:AV724329 /FEA=EST /DB_XREF=gi:10828609 /DB_XREF=est:AV724329 /CLONE=HTBAYE09 /UG=Hs.26612 ESTs
206767_AT 1.237061736 RNA binding motif, single stranded interacting protein
212865_S_AT 1.237617756 collagen, type XIV, alpha 1 (undulin)
205622_AT 1.23863447 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
227550_AT 1.24163209 Consensus includes gb:AW242720 /FEA=EST /DB_XREF=gi:6576565 /DB_XREF=est:xm90c07.x1 /CLONE=IMAGE:2691468 /UG=Hs.94694 Homo sapiens cDNA FLJ10561 fis, clone NT2RP2002672
227400_AT 1.245481895 nuclear factor I/X (CCAAT-binding transcription factor)
227095_AT 1.247538855 Consensus includes gb:AU151151 /FEA=EST /DB_XREF=gi:11012672 /DB_XREF=est:AU151151 /CLONE=NT2RP2004501 /UG=Hs.11493 Homo sapiens cDNA FLJ13536 fis, clone PLACE1006521
213993_AT 1.249679508 spondin 1, (f-spondin) extracellular matrix protein
200091_S_AT 1.249883518 ribosomal protein S25
226769_AT 1.25158845 Consensus includes gb:AI802391 /FEA=EST /DB_XREF=gi:5367863 /DB_XREF=est:tc33c04.x1 /CLONE=IMAGE:2066406 /UG=Hs.32478 ESTs
235343_AT 1.252594587 Consensus includes gb:AI961235 /FEA=EST /DB_XREF=gi:5753948 /DB_XREF=est:wt15d02.x1 /CLONE=IMAGE:2507523 /UG=Hs.96885 ESTs
215489_X_AT 1.25463764 Homer, neuronal immediate early gene, 3
226227_X_AT 1.255386587 ribosomal protein L10
221253_S_AT 1.255591702 thioredoxin related protein
225293_AT 1.257051538 KIAA1870 protein
212070_AT 1.257819537 G protein-coupled receptor 56
201004_AT 1.258887314 signal sequence receptor, delta (translocon-associated protein delta)
225524_AT 1.260794285 Consensus includes gb:AU152178 /FEA=EST /DB_XREF=gi:11013699 /DB_XREF=est:AU152178 /CLONE=NT2RP3000356 /UG=Hs.5897 Homo sapiens mRNA; cDNA DKFZp586P1622 (from clone DKFZp586P1622)
200025_S_AT 1.266750238 ribosomal protein L27
201798_S_AT 1.267666985 fer-1-like 3, myoferlin (C. elegans)
200999_S_AT 1.268554366 cytoskeleton-associated protein 4
205047_S_AT 1.272415146 asparagine synthetase
232568_AT 1.273750665 Consensus includes gb:AU145658 /FEA=EST /DB_XREF=gi:11007179 /DB_XREF=est:AU145658 /CLONE=HEMBA1005426 /UG=Hs.287447 Homo sapiens cDNA FLJ11733 fis, clone HEMBA1005426
226731_AT 1.277394682 Consensus includes gb:AA156873 /FEA=EST /DB_XREF=gi:1728488 /DB_XREF=est:zl20h08.s1 /CLONE=IMAGE:502527 /UG=Hs.184411 albumin
230708_AT 1.278154867 Consensus includes gb:AA206141 /FEA=EST /DB_XREF=gi:1801529 /DB_XREF=est:zq54h06.s1 /CLONE=IMAGE:645467 /UG=Hs.86237 ESTs
224915_X_AT 1.278690668 ribosomal protein L10
224874_AT 1.285040296 Consensus includes gb:N32181 /FEA=EST /DB_XREF=gi:1152580 /DB_XREF=est:yy25c09.s1 /CLONE=IMAGE:272272 /UG=Hs.279591 Homo sapiens clone 25056 mRNA sequence
221004_S_AT 1.285059625 integral membrane protein 3
218718_AT 1.288837342 platelet derived growth factor C
223044_AT 1.28976985 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 3
201540_AT 1.29071587 four and a half LIM domains 1
204073_S_AT 1.291992594 chromosome 11 open reading frame 9
209250_AT 1.29301844 degenerative spermatocyte homolog, lipid desaturase (Drosophila)
212419_AT 1.293633012 Homo sapiens, similar to Y43E12A.2.p, clone MGC:33537 IMAGE:4821347, mRNA, complete cds
210987_X_AT 1.295835332 tropomyosin 1 (alpha)
235527_AT 1.300030842 Consensus includes gb:U55983 /FEA=EST /DB_XREF=gi:1354539 /DB_XREF=est:HSU55983 /CLONE=25150 /UG=Hs.290270 ESTs
225868_AT 1.300252579 gene overexpressed in astrocytoma
200088_X_AT 1.302539027 ribosomal protein L12
205582_S_AT 1.306594707 gamma-glutamyltransferase-like activity 1
201590_X_AT 1.310067911 annexin A2
207191_S_AT 1.314983958 immunoglobulin superfamily containing leucine-rich repeat
221530_S_AT 1.31612576 basic helix-loop-helix domain containing, class B, 3
203570_AT 1.320595376 lysyl oxidase-like 1
233607_AT 1.323745885 Consensus includes gb:AU145679 /FEA=EST /DB_XREF=gi:11007200 /DB_XREF=est:AU145679 /CLONE=HEMBA1005497 /UG=Hs.301626 Homo sapiens cDNA FLJ11739 fis, clone HEMBA1005497
212489_AT 1.325150391 collagen, type V, alpha 1
225541_AT 1.334165509 Bernardinelli-Seip congenital lipodystrophy 2 (seipin)
219332_AT 1.337767498 hypothetical protein FLJ23471
238935_AT 1.338252224 Consensus includes gb:AW958475 /FEA=EST /DB_XREF=gi:8148159 /DB_XREF=est:EST370545 /UG=Hs.293947 ESTs, Weakly similar to I38022 hypothetical protein H.sapiens
217757_AT 1.339761129 alpha-2-macroglobulin
213503_X_AT 1.340824578 annexin A2
227628_AT 1.340990903 Consensus includes gb:AL571557 /FEA=EST /DB_XREF=gi:12928970 /DB_XREF=est:AL571557 /CLONE=CS0DI024YP08 (3 prime) /UG=Hs.252280 Rho guanine nucleotide exchange factor (GEF) 1
231579_S_AT 1.341554022 Consensus includes gb:BE968786 /FEA=EST /DB_XREF=gi:10579491 /DB_XREF=est:601649975F1 /CLONE=IMAGE:3933691 /UG=Hs.6441 Homo sapiens mRNA; cDNA DKFZp586J021 (from clone DKFZp586J021)
244498_X_AT 1.341921008 hypothetical protein FLJ22795
210427_X_AT 1.357240325 annexin A2
213258_AT 1.358572258 tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
228333_AT 1.361484587 Consensus includes gb:AI912571 /FEA=EST /DB_XREF=gi:5632426 /DB_XREF=est:we11c04.x1 /CLONE=IMAGE:2340774 /UG=Hs.293676 ESTs
228376_AT 1.367416558 Consensus includes gb:AI972498 /FEA=EST /DB_XREF=gi:5769244 /DB_XREF=est:wr38c04.x1 /CLONE=IMAGE:2489958 /UG=Hs.97469 ESTs, Highly similar to A39769 N-acetyllactosaminide alpha-1,3-galactosyltransferase H.sapiens
202992_AT 1.369860753 complement component 7
216589_AT 1.369973892 Consensus includes gb:AL031276 /DEF=Human DNA sequence from clone 1118D24 on chromosome 1p36.11-36.33. Contains part of a novel gene similar to worm genes T08G11.1 and C25H3.9, part of a 60S Ribosomal Protein L10 LIKE (pseudo)gene and two 3 exons of the TNFR2 gene for Tumor Necrosi... /FEA=CDS_3 /DB_XREF=gi:3947780 /UG=Hs.247773 Human DNA sequence from clone 1118D24 on chromosome 1p36.11-36.33. Contains part of a novel gene similar to worm genes T08G11.1 and C25H3.9, part of a 60S Ribosomal Protein L10 LIKE (pseudo)gene and two 3 exons of the TNFR2 gene for Tumor Necrosis Factor
231956_AT 1.37058989 KIAA1618 protein
232914_S_AT 1.374130669 synaptotagmin-like 2
206336_AT 1.374366046 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)
201939_AT 1.381746061 serum-inducible kinase
201189_S_AT 1.387216871 inositol 1,4,5-triphosphate receptor, type 3
230061_AT 1.39036339 Consensus includes gb:AW338625 /FEA=EST /DB_XREF=gi:6835251 /DB_XREF=est:ha63a02.x1 /CLONE=IMAGE:2878346 /UG=Hs.22120 ESTs
212646_AT 1.391579711 KIAA0084 protein
212190_AT 1.397987102 serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
211340_S_AT 1.398229327 melanoma cell adhesion molecule
214247_S_AT 1.399778156 dickkopf homolog 3 (Xenopus laevis)
225725_AT 1.399942478 Consensus includes gb:AL533234 /FEA=EST /DB_XREF=gi:12796727 /DB_XREF=est:AL533234 /CLONE=CS0DN003YO15 (3 prime) /UG=Hs.26418 ESTs
218960_AT 1.401709562 transmembrane protease, serine 4
200986_AT 1.402768462 serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary)
225520_AT 1.404939056 Consensus includes gb:AL133260 /DEF=Human DNA sequence from clone RP1-292B18 on chromosome 6q24.3-25.3. Contains a 60S ribosomal protein L32 (RPL32) pseudogene, the 3 end of the gene for a novel protein similar to NADP+ dependent methylenetetrahydrofolat
213332_AT 1.410529364 Homo sapiens cDNA FLJ39399 fis, clone PLACE6011041
210986_S_AT 1.415326446 tropomyosin 1 (alpha)
201012_AT 1.41609642 annexin A1
214770_AT 1.418908197 macrophage scavenger receptor 1
222925_AT 1.420398606 RU2S
203476_AT 1.428852653 trophoblast glycoprotein
210933_S_AT 1.42941576 hypothetical protein MGC4655
209708_AT 1.435248054 DKFZP564G202 protein
200795_AT 1.437745827 SPARC-like 1 (mast9, hevin)
217360_X_AT 1.44066345 Consensus includes gb:AJ275408 /DEF=Homo sapiens partial IGVH3 gene for immunoglobulin heavy chain V region, case 1, cell Mo VI 162 /FEA=CDS /DB_XREF=gi:7573079 /UG=Hs.272363 Homo sapiens partial IGVH3 gene for immunoglobulin heavy chain V region, case 1, cell Mo VI 162
211719_X_AT 1.441332362 fibronectin 1
210495_X_AT 1.444417445 fibronectin 1
202766_S_AT 1.445284138 fibrillin 1 (Marfan syndrome)
224694_AT 1.446756925 tumor endothelial marker 8
234994_AT 1.456358161 KIAA1913 protein
223395_AT 1.456915192 DKFZP586L2024 protein
209114_AT 1.463996851 tetraspan 1
201141_AT 1.470896057 glycoprotein (transmembrane) nmb
212464_S_AT 1.471667088 fibronectin 1
230865_AT 1.473488244 Consensus includes gb:N29837 /FEA=EST /DB_XREF=gi:1148357 /DB_XREF=est:yw93e11.s1 /CLONE=IMAGE:259820 /UG=Hs.25205 ESTs
216442_X_AT 1.481522822 fibronectin 1
202403_S_AT 1.498542655 collagen, type I, alpha 2
205044_AT 1.500072626 gamma-aminobutyric acid (GABA) A receptor, pi
218002_S_AT 1.50143269 chemokine (C-X-C motif) ligand 14
205890_S_AT 1.501834772 ubiquitin D
222549_AT 1.504922194 claudin 1
227006_AT 1.508429008 protein phosphatase 1, regulatory (inhibitor) subunit 14A
228367_AT 1.508627522 heart alpha-kinase
203477_AT 1.51069519 collagen, type XV, alpha 1
214321_AT 1.52285407 nephroblastoma overexpressed gene
239519_AT 1.533746711 Consensus includes gb:AA927670 /FEA=EST /DB_XREF=gi:3076490 /DB_XREF=est:om72a05.s1 /CLONE=IMAGE:1552688 /UG=Hs.131704 ESTs
207173_X_AT 1.536504615 cadherin 11, type 2, OB-cadherin (osteoblast)
228750_AT 1.542651522 Consensus includes gb:AI693516 /FEA=EST /DB_XREF=gi:4970856 /DB_XREF=est:wd43e03.x1 /CLONE=IMAGE:2330908 /UG=Hs.28625 ESTs
201438_AT 1.545904663 collagen, type VI, alpha 3
204933_S_AT 1.564410582 tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
203798_S_AT 1.575116185 visinin-like 1
225681_AT 1.58766942 Consensus includes gb:AA584310 /FEA=EST /DB_XREF=gi:2368919 /DB_XREF=est:nn79g01.s1 /CLONE=IMAGE:1090128 /UG=Hs.283713 ESTs, Weakly similar to ORF YGL050w S.cerevisiae
213994_S_AT 1.600995219 spondin 1, (f-spondin) extracellular matrix protein
201645_AT 1.601544517 tenascin C (hexabrachion)
204150_AT 1.60514469 stabilin 1
204438_AT 1.607478454 mannose receptor, C type 1
226621_AT 1.608496225 fibrinogen, gamma polypeptide
202404_S_AT 1.625425914 collagen, type I, alpha 2
219359_AT 1.625667544 hypothetical protein FLJ22635
221872_AT 1.625850269 retinoic acid receptor responder (tazarotene induced) 1
209774_X_AT 1.632070072 chemokine (C-X-C motif) ligand 2
205547_S_AT 1.652144874 transgelin
217767_AT 1.652843581 complement component 3
223218_S_AT 1.67088194 molecule possessing ankyrin repeats induced by lipopolysaccharide (MAIL), homolog of mouse
214803_AT 1.680222335 Homo sapiens mRNA; cDNA DKFZp564N1116 (from clone DKFZp564N1116)
209960_AT 1.693139918 hepatocyte growth factor (hepapoietin A; scatter factor)
204304_S_AT 1.708433923 prominin-like 1 (mouse)
201852_X_AT 1.713217834 collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant)
208451_S_AT 1.716268712 complement component 4B
215076_S_AT 1.717776215 collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant)
204932_AT 1.721284296 tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
201744_S_AT 1.752427367 lumican
216598_S_AT 1.771133304 chemokine (C-C motif) ligand 2
201666_AT 1.797990004 tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase inhibitor)
202357_S_AT 1.812934811 B-factor, properdin
211161_S_AT 1.814980251 gb:AF130082.1 /DEF=Homo sapiens clone FLC1492 PRO3121 mRNA, complete cds. /FEA=mRNA /PROD=PRO3121 /DB_XREF=gi:11493468 /UG=Hs.119571 collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) /FL=gb:AF130082.1
229659_S_AT 1.847078972 Consensus includes gb:BE501712 /FEA=EST /DB_XREF=gi:9704120 /DB_XREF=est:hw34c04.x1 /CLONE=IMAGE:3184806 /UG=Hs.205126 Homo sapiens cDNA: FLJ22667 fis, clone HSI08385
203868_S_AT 1.8584063 vascular cell adhesion molecule 1
214428_X_AT 1.868320095 complement component 4A
202238_S_AT 1.872072166 nicotinamide N-methyltransferase
203892_AT 1.925641314 WAP four-disulfide core domain 2
208747_S_AT 1.967306306 complement component 1, s subcomponent
227140_AT 1.974210876 Consensus includes gb:AI343467 /FEA=EST /DB_XREF=gi:4080673 /DB_XREF=est:tb97a02.x1 /CLONE=IMAGE:2062250 /UG=Hs.28792 Homo sapiens cDNA FLJ11041 fis, clone PLACE1004405
202310_S_AT 1.986878496 collagen, type I, alpha 1
226147_S_AT 2.017873731 Consensus includes gb:AA838075 /FEA=EST /DB_XREF=gi:2913732 /DB_XREF=est:oe93h05.s1 /CLONE=IMAGE:1419225 /UG=Hs.205126 Homo sapiens cDNA: FLJ22667 fis, clone HSI08385
226535_AT 2.072503948 Consensus includes gb:AK026736.1 /DEF=Homo sapiens cDNA: FLJ23083 fis, clone LNG06541, highly similar to IR2005735 Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 2005735. /FEA=mRNA /DB_XREF=gi:10439657 /UG=Hs.57664 Homo sapiens mRNA full leng
225353_S_AT 2.090924327 Consensus includes gb:AI184968 /FEA=EST /DB_XREF=gi:3735606 /DB_XREF=est:qe51c05.x1 /CLONE=IMAGE:1742504 /UG=Hs.94953 ESTs, Highly similar to C1HUQC complement subcomponent C1q chain C precursor H.sapiens
202953_AT 2.158512953 complement component 1, q subcomponent, beta polypeptide
212067_S_AT 2.168640328 complement component 1, r subcomponent
218232_AT 2.186166831 complement component 1, q subcomponent, alpha polypeptide
227697_AT 2.191502539 STAT induced STAT inhibitor 3
216834_AT 2.470272934 regulator of G-protein signalling 1
217239_X_AT 2.49895167 Consensus includes gb:AF044592 /DEF=Homo sapiens lymphocyte-predominant Hodgkins disease case 4 immunoglobulin heavy chain gene, variable region, partial cds /FEA=CDS /DB_XREF=gi:2852420 /UG=Hs.248077 Homo sapiens lymphocyte-predominant Hodgkins disease case 4 immunoglobulin heavy chain gene, variable region, partial cds
202988_S_AT 2.51395452 regulator of G-protein signalling 1
202018_S_AT 2.589367704 lactotransferrin
244567_AT 2.77086294 Consensus includes gb:BG165613 /FEA=EST /DB_XREF=gi:12672316 /DB_XREF=est:602343781F1 /CLONE=IMAGE:4453556 /UG=Hs.125395 ESTs
204259_AT 2.900639089 matrix metalloproteinase 7 (matrilysin, uterine)
202237_AT 2.933157011 nicotinamide N-methyltransferase

Genes identified as changing as a function of age within the kidney are included in this list (n=447). Genes are identified by Affymetrix Probe ID in the first column, and are arranged in order of fold change over a span of 50 years (second column). Gene descriptions are in the third column.