Transcriptional profiling of aging in human muscle reveals a common aging signature

 

Supplemental Tables

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Table 1. Patients recruited by age group

 

Table 2. Age-regulated gene sets in muscle

 

Table 3. Age-regulation of gene sets in three human tissues

 

Table 4. Age-regulation of the electron transport chain in three species

 

Table S1. Clinical data

 

Table S2. 250 age-regulated genes (p < 0.001), arranged by slope with age

 

Table S3. 624 gene sets assayed for age-regulation

 

Table S4. Contributing genes in gene sets age-regulated in muscle

 

Table S5. Type II/Type I muscle fiber diameter ratios of 32 patients

 

Table S6. 92 age-regulated genes which predict Type II/Type I ratio

 

Table S7. 114 Type II/Type I-regulated genes which predict age

 

Table S8. Significant overlap between sets of age-regulated and Type II/Type I-regulated genes

 

Table S9. Contributing genes in gene sets commonly age-regulated in muscle, kidney, and brain

 

Table S10. Aging coefficients of 11512 genes in mouse kidney

 

Table S11. Correlation of age-regulated genes in three tissues

 

Table S12. Spearman correlations between tissues for age-regulated gene sets