Table 1. Feeding response genes A. Functional classes Fold enrichment Number in Total on in Feeding Feeding Gene classa Array responseb response Referencec Total number of gene 17761 446 Nuclear: nucleolus 23 13.7 8 tRNA Synthetase Genes 30 9.2 7 Translation Factors 43 9.2 10 RNA Processing/Modification 71 6.7 12 Endoplasmic Reticulum 63 4.4 7 Mitochondrial 179 4.2 19 Protein Expression 390 3.9 39 Kim et al., 2001 RNA Binding 151 3.4 13 Germ Line-Enriched 508 2.5 32 Reinke et al., 2000 Biosynthesis 478 2.4 29 Kim et al., 2001 Muscle Expressed Genes 1329 2.1 70 P. Roy et al., 2002 Worm-Yeast Orthologs 1921 1.9 94 Kim et al., 2001 B. Gene expression mountains Fold enrichment Number in Total on in Feeding Feeding Gene classa Array responseb response Commentsd Genome 17761 446 Mount 41 7 11.3 2 protein expression Mount 40 8 14.8 3 protein expression Mount 20 160 11.4 46 germ line, biosynthesis, protein expression, heat shock Mount 18 190 4.6 22 germ line, oocyte, biosynthesis, protein synthesis Mount 05 978 2.3 56 Mount 02 1465 2.2 80 germ line, oocyte, operons aOver-represented functional classes in the feeding response gene groups. For clarity, gene groups with p>0.001 are not listed. See Supplemental Data for full comparisons. Gene lists are shown in Supplemental Table [5]. bAll representation factors are significant at p<0.001. The probability was determined using the normal approximation of the hypergeometric probability distribution. cFunctional classes are from Proteome except where noted. dFunctional groups over-represented in the mountains (Kim et al., 2001)