| MEG | Organism | Name | Description | |
| MEG1316 | Center | |||
| Fly | ANK | Dank1 CG1651 CG32008 ankyrin | ||
| Human | AUTS2.FLJ22206;KIAA0697;NY-BR-16.gene trap ankyrin repeat. | |||
| Worm | unc-44 A013 B0350.2 | Set of ankyrin-related proteins generated by alternate splicing, required for axonal guidance and proper axon fasciculation | ||
| Yeast | HOS4 | |||
| MEG623 | p-value | 0.00112 | ||
| Fly | no data | cam | CAM Cal CaM dCaM 3909 D-CaM DmCalm Cal49A CG8472 l(2)3909 l(2)03909 calmodulin | |
| Human | 0.52 (327) | calmodulin 1 (phosphorylase kinase, delta) | CALM1.CAMI;PHKD;DD132;CALML2.calmodulin 1 (phosphorylase kinase, delta). | |
| Worm | 0.71 (940) | cmd-1 T21H3.3 | Calmodulin | |
| Yeast | -0.050 (632) | CMD1 | master regulator of calcium mediated signalling calmodulin Null mutant is inviable | |
| MEG610 | p-value | 0.00196 | ||
| Fly | 0.25 (150) | CG6355 | ||
| Human | 0.45 (839) | C1orf15... | ||
| Worm | 0.31 (881) | VF11C1L.1 C05E7.5 | Protein with strong similarity to S. cerevisiae Fab1p, a phosphatidylinositol-3-phosphate 5-kinase involved in orientation or separation of mitotic chromosomes | |
| Yeast | 0.45 (632) | FAB1 | May regulate vacuole homeostasis. Catalyzes formation of phosphatidylinositol-3,5-bisphosphate via phosphorylation of phosphatidylinositol-3-phosphate. 1-phosphatidylinositol-3-phosphate 5-kinase Null mutant is temperature-sensitive. Mutation causes pleiotropic effects on nuclear migration and orientation, and separation of mitotic chromosomes (forms aploid and binucleate cells); has defects in vacuolar function and morphology. | |
| MEG2007 | p-value | 0.00582 | ||
| Fly | 0.50 (150) | G | Gi DG DG1 Gai G65A G--65A CG10060 Gi-alpha Galpha i G protein alpha-subunit G protein alpha subunit G protein o subunit 65A G protein o subunit 65A G-o65A: G protein o subunit 65A | |
| Human | 0.48 (772) | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | GNAI1.Gi.guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1. | |
| Worm | 0.70 (937) | goa-1 C26C6.2 | Member of the G-protein alpha subunit protein family apprently involved in synaptic transmission may have a role in regulating centrosome movement during early embryogenesis | |
| Yeast | 0.22 (632) | GPA2 | homologous to mammalian G proteins; potential role in regulation of cAMP levels nucleotide binding regulatory protein Null mutant is viable | |
| MEG1120 | p-value | 0.00711 | ||
| Fly | 0.56 (150) | No Name | No Description | |
| Human | 0.53 (772) | OAZIN.PCF11P;KIAA0824.PCF11p homolog. | ||
| Worm | 0.64 (944) | R144.2 | Protein of unknown function, has moderate similarity to human KIAA0824 protein isolated from a brain cDNA library , has weak similarity to S. cerevisiae Pcf11p | |
| Yeast | 0.17 (632) | PCF11 | pre-mRNA cleavage and polyadenylation factor I component, interacts with Rna14p and Rna15p cleavage and polyadenylation factor CF I component involved in pre-mRNA 3'-end processing Null mutant is inviable; pcf11 (ts) mutations are synthetically lethal with rna14 (ts) and rna15 (ts) mutations | |
| MEG1057 | p-value | 0.00858 | ||
| Fly | 0.60 (150) | fet | CG5067 capicua E(Dl)D49 fettucine Enhancer of Delta D49 | |
| Human | 0.61 (509) | capicua homolog (Drosophila) | CIC.KIAA0306.capicua (Drosophila) homolog. | |
| Worm | 0.31 (187) | T22H6.6 | Protein containing an HMG box, has similarity to human KIAA0306 protein isolated from a brain cDNA library | |
| Yeast | 0.19 (632) | ROX1 | The ROX1 gene encodes a heme-induced repressor of hypoxic genes in yeast. HMG-domain site-specific DNA binding protein. The null mutant is viable but misexpresses several heme-regulated genes. | |
| MEG1976 | p-value | 0.00951 | ||
| Fly | 0.033 (150) | No Name | No Description | |
| Human | 0.82 (432) | PRP8 pre-mRNA processing factor 8 homolog (yeast) | PRPF8.PRP8;RP13;HPRP8;PRPC8.U5 snRNP-specific protein. | |
| Worm | 0.63 (944) | C50C3.6 | Putative U5 snRNA-associated splicing factor PRP8, predicted to be involved in association of U5 snRNP with U4 U6 snRNP and to promote both catalytic steps of splicing | |
| Yeast | 0.026 (632) | PRP8 | protein involved in mRNA splicing; lies at the catalytic center of the spliceosome; makes extensive contacts with the U5 snRNA and with the pre-mRNA U5 snRNP and spliceosome component Null mutant is inviable; synthetic lethal with U2 snRNA (LSR1); blocks pre-mRNA splicing in vivo and in vitro | |
| MEG412 | p-value | 0.00958 | ||
| Fly | no data | No Name | No Description | |
| Human | 0.59 (684) | HNRPR.AN11.WD-repeat protein. | ||
| Worm | 0.47 (182) | F53C11.7 | Protein of unknown function, has strong similarity to human HAN11 WD repeat protein Hs.154397 isolated from a liver cDNA library | |
| Yeast | 0.15 (632) | No Name | No Description | |
| MEG6039 | p-value | 0.0106 | ||
| Fly | 0.096 (150) | No Name | No Description | |
| Human | 0.40 (684) | heparan sulfate proteoglycan 2 (perlecan) | HSPG2.PLC;SJA;SJS;SJS1.heparan sulfate proteoglycan 2 (perlecan). | |
| Worm | 0.77 (934) | unc-52 ZC101.2 | Perlecan, a muscle protein, member of the Immunoglobulin superfamily | |
| MEG2524 | p-value | 0.0177 | ||
| Fly | 0.51 (150) | dAbi | CG9749 Ablphilin Abelson Interacting Protein | |
| Human | 0.82 (509) | spectrin SH3 domain binding protein 1 | SSH3BP1.ABI1;E3B1;NAP1;ABI-1.spectrin SH3 domain binding protein 1.Binds the SH3 domains of EPS8 and of spectrin (SPTA1); contains SH3 domain|Proteome | |
| Worm | 0.26 (900) | B0336.6 | Protein with strong similarity to human SSH3BP1, a spectrin SH3 domain binding protein | |
| MEG2400 | p-value | 0.0199 | ||
| Fly | 0.42 (150) | PKC | 98F nPKC Pkc3 Dpkc3 Nc98F CG1954 PKC 98F dPKC98F PKC d98F PKC-brain protein kinase C Neural-conserved-at-98F | |
| Human | 0.54 (187) | protein kinase C, epsilon | PRKCE.PKCE.protein kinase C, epsilon. | |
| Worm | 0.70 (744) | F46F6.2 | Serine threonine protein kinase with strong similarity to human, D. melanogaster, and S. cerevisiae protein kinase C isoforms, important for establishment of embryonic polarity | |
| Yeast | 0.16 (632) | PKC1 | Protein Kinase C The null mutant is inviable and lyses rapidly in hypotonic media. Cells lacking PKC1 arrest growth with small buds at a point after DNA replication but prior to mitosis. | |
| MEG643 | p-value | 0.0230 | ||
| Fly | 0.14 (150) | PDK | PDK1 dPDK1 dPDK-1 CG1201 CG1210 Dstpk61 DSTPK61 serine/threonine protein kinase. Phosphoinositide dependent kinase 1 | |
| Human | 0.56 (882) | 3-phosphoinositide dependent protein kinase-1 | PDPK1.PDK1.3-phosphoinositide dependent protein kinase-1.Protein kinase may mediate signalling by insulin or growth factors; contains a pleckstrin homology domain|Proteome | |
| Worm | 0.51 (928) | No Name | No Description | |
| Yeast | 0.35 (632) | PKH2 | Pkb-activating Kinase Homologue Null mutant is viable; pkh1, pkh2 double mutant is lethal | |
| MEG6269 | p-value | 0.0257 | ||
| Fly | 0.46 (150) | No Name | No Description | |
| Human | 0.15 (1145) | SCA11.mig-2.. | ||
| Worm | 0.76 (926) | unc-112 C47E8.7 | Muscle protein functions in the attachment of the myofilament lattice to basal cell membranes | |
| MEG3625 | p-value | 0.0275 | ||
| Fly | 0.29 (150) | p45 | YPS Yps p57 CG5654 Ypsilon Schachtel | |
| Human | 0.57 (772) | cold shock domain protein A | CSDA.DBPA;dbpA.cold shock domain protein A.Member of a family of transcriptional regulators; binds and represses the promoter of the (GM-CSF) gene; contains a cold-shock domain|Proteome | |
| Worm | 0.78 (944) | F33A8.3 | Protein contains a putative CSP cold shock protein domain, has strong similarity to human NSEP1 protein, nuclease sensitive RNA-binding protein with transcription factor properties | |
| MEG4671 | p-value | 0.0280 | ||
| Fly | 0.43 (150) | ZFH-2 | Zfh-2 zfh-2 CG1449 | |
| Human | 0.34 (1059) | AT-binding transcription factor 1 | ATBF1..AT-binding transcription factor 1. | |
| Worm | 0.69 (918) | ZC123.3 | Putative paralog of C. elegans ZC123.2 gene product | |
| MEG3840 | p-value | 0.0287 | ||
| Fly | no data | dlg | DLG Dlg DlgA misb dlgA dlg-A DLG-A dlg-1 CG1725 CG1730 Drodlg l(1)L11 l(1)bwn l(1)dlg l(1)G19 l(1)dlg1 l(1)10Bf d. lg.-1 l(1)lpr-2 l(1)dlg-1 discslarge l(1)d.lg-1 Discs-Large discs large l(1)l.pr.-2 Discs-large l(1)d.lg.-1 discs-large Discs large l(1)discs large lethal(2)discs large lethal(1)discs-large lethal(1)discs large lethal(1)benign wing imaginal disc neoplasm l(1)bwn: lethal(1)benign wing imaginal disc neoplasm | |
| Human | 0.66 (772) | discs, large (Drosophila) homolog 1 | DLG1.hdlg;SAP97.discs, large (Drosophila) homolog 1. | |
| Worm | 0.79 (931) | dlg-1 C25F6.2 | Putative guanylate kinase strongly similar to D. melanogaster DLG1 discs large 1 which is required for zonula adherens formation | |
| MEG709 | p-value | 0.0303 | ||
| Fly | 0.17 (150) | No Name | No Description | |
| Human | 0.49 (595) | FAIM2.AD-005.KIAA1007 protein. | ||
| Worm | 0.71 (901) | F57B9.2 | Protein with similarity to S. cerevisiae Cdc39p, a nuclear protein that negatively affects basal transcription from many promoters | |
| Yeast | 0.024 (632) | CDC39 | Required for Start B in mitosis and spindle pole body separation at meiosis I basal transcription inhibitor|transcriptional regulator Null mutant is inviable; arrests in G(sub)1 at pachytene at the mononucleate stage with duplicated, unseparated spindle pole bodies and no spindles; temperature sensitive mutation which causes increased basal transcription of many genes | |
| MEG5592 | p-value | 0.0356 | ||
| Fly | 0.055 (148) | No Name | No Description | |
| Human | 0.57 (582) | CLSTN3..KIAA0680 gene product. | ||
| Worm | 0.65 (754) | F26H9.2 | Protein with strong similarity to human Hs.102471 protein, mRNA for KIAA0680 protein, isolated from brain cDNA library | |
| MEG4456 | p-value | 0.0370 | ||
| Fly | 0.42 (136) | Robo | robo1 Robo1 dRobo Robo-1 dRobo1 CG13521 D-Robo1 CT32892 Roundabout 1 | |
| Human | 0.51 (686) | roundabout, axon guidance receptor, homolog 2 (Drosophila) | ROBO2.KIAA1568..Roundabout 2; involved in axon guidance; member of the immunoglobulin superfamily|Proteome | |
| Worm | 0.75 (925) | sax-3 ZK377.2 ZK377.3 | Predicted transmembrane protein involved in axon guidance of motor neurons both to and within the ventral nerve cord member of the Immunoglobin superfamily | |
| MEG3329 | p-value | 0.0385 | ||
| Fly | 0.48 (150) | No Name | No Description | |
| Human | 0.28 (509) | C1orf34... | ||
| Worm | 0.68 (920) | F28F5.3 | Protein with weak similarity to H. sapiens Hs.22599 Homo sapiens mRNA for KIAA0705 protein, complete cds | |
| MEG1766 | p-value | 0.0403 | ||
| Fly | no data | CG2161 | l(3)03834 | |
| Human | 0.59 (684) | CCR4-NOT transcription complex, subunit 2 | CNOT2.NOT2;CDC36;NOT2H;HSPC131.CCR4-NOT transcription complex, subunit 2.NOT-CCR4 transcriptional regulation complex subunit 4; may function as a transcription factor|Proteome | |
| Worm | 0.71 (950) | B0286.4 | Protein with strong similarity to D. melanogaster RGA Regena protein | |
| Yeast | -0.025 (632) | CDC36 | Required for Start B in mitosis and for meiosis I spindle pole body separation basal transcription inhibitor|transcriptional regulator Null mutant is viable, cdc36 mutant arrests in G(sub)1; forms shmoo morphology at restrictive temperature, arrests at pachytene at the mononucleate stage with duplicated spindle pole bodies and no spindles | |
| MEG2481 | p-value | 0.0478 | ||
| Fly | 0.57 (150) | SZ1 | sci who qkr P62 How stru KH93F Who/How CG10293 struthio scorpion l(3)j5B5 l(3)j5D5 l(3)s2612 wings held out wings held-out KH motif at 93F who: wings held out quaking related, 93F | |
| Human | 0.16 (1086) | CRSP9.QK;QK3..Very strongly similar to murine qk; putative RNA-binding protein|Proteome | ||
| Worm | 0.75 (936) | T21G5.5 | Putative paralog of C. elegans GLD-1 which encodes an RNA-binding protein required for transition from mitosis to meiosis during spermatogenesis and oogenesis in hermaphrodites | |
| MEG4016 | p-value | 0.0488 | ||
| Fly | 0.48 (150) | MYOTUBULARIN-like | ||
| Human | 0.31 (772) | myotubularin related protein 3 | MTMR3.ZFYVE10;KIAA0371;FYVE-DSP1.myotubularin-related protein 3 isoform c. | |
| Worm | 0.58 (948) | T24A11.1 | Member of the myotubularin protein family |