MEG Organism   Name Description
MEG1550   Center    
  Fly   No Name No Description
  Human   adenylosuccinate lyase ADSL..adenylosuccinate lyase.
  Worm   R06C7.5 Putative adenylosuccinate lyase, predicted to carry out the eighth step in de novo purine biosynthesis
  Yeast   ADE13 Adenylosuccinate Lyase adenylosuccinate lyase Unable to grow on complete media with glucose or fructose as a carbon source, but can grow with glycerol or ethanol
MEG1010 p-value 0.000662    
  Fly 0.31 (138) Ade5 CG3989 AIRc-SAICARs AIR-carboxylase-SAICAR synthetase AIRc-SAICARs: AIR-carboxylase-SAICAR synthetase
  Human 0.71 (1176) phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase PAICS.AIRC;PAIS;ADE2H1.phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase.
  Worm 0.35 (873) B0286.3 Member of the AIR carboxylase protein family
  Yeast 0.46 (639) ADE1 phosphoribosyl amino imidazolesuccinocarbozamide synthetase phosphoribosyl amino imidazolesuccinocarbozamide synthetase Null mutant is viable and adenine auxotroph; ade1 mutants produce red pigment when grown in media containing low lvels of adenine.
MEG318 p-value 0.000831    
  Fly 0.58 (144) SAHH ahcY Ahcy13 CG11654 AdoHcyase S-Adenosyl-L-homocysteine hydrolase
  Human 0.70 (772) S-adenosylhomocysteine hydrolase AHCY.SAHH.S-adenosylhomocysteine hydrolase.
  Worm 0.60 (939) dpy-14 CEAHH K02F2.2 Putative adenosylhomocysteinase
  Yeast 0.42 (639) SAH1 putative S-adenosyl-L-homocysteine hydrolase S-adenosyl-L-homocysteine hydrolase (putative)
MEG6188 p-value 0.00108    
  Fly 0.77 (146) CG4170 EP(2)0812 BG:DS00929.13 vasa intronic gene
  Human 0.78 (772) C20orf188.CGI-55;DKFZp564M2423.PAI-1 mRNA-binding protein.Moderately similar to human Ki-157 intracellular antigen|Proteome
  Worm 0.50 (944) F56D12.5 Protein with weak similarity to C. elegans T01C3.7 Member of the fibrillarin protein family
MEG1364 p-value 0.00171    
  Fly 0.54 (150) CG2867 transcript D
  Human 0.10 (999) phosphoribosyl pyrophosphate amidotransferase PPAT.GPAT;ATASE.phosphoribosyl pyrophosphate amidotransferase proprotein.
  Worm 0.47 (929) T04A8.5 Putative glutamine phosphoribosyl pyrophosphate PRPP amidotransferase, predicted to catalyze the first step in de novo purine biosynthesis
  Yeast 0.75 (638) ADE4 phosphoribosylpyrophosphate amidotransferase phosphoribosylpyrophosphate amidotransferase Adenine requiring
MEG224 p-value 0.00201    
  Fly 0.75 (150) No Name No Description
  Human 0.73 (686) chaperonin containing TCP1, subunit 7 (eta) CCT7.Ccth;Nip7-1.chaperonin containing TCP1, subunit 7 (eta).
  Worm 0.30 (936) T10B5.5 Member of the chaperonin complex protein family
  Yeast 0.44 (639) CCT7 Required for assembly of microtubules and actin in vivo chaperonin containing T-complex subunit seven component
MEG1733 p-value 0.00236    
  Fly 0.51 (150) No Name No Description
  Human 0.81 (595) chaperonin containing TCP1, subunit 6B (zeta 2) CCT6B.Cctz2;CCTZ-2;TSA303.chaperonin containing TCP1, subunit 6B (zeta 2).
  Worm 0.62 (946) cct-6 F01F1.8 Member of the chaperonin complex family
  Yeast 0.097 (639) CCT6 cytoplasmic chaperonin of the Cct ring complex (previously called TCP1 or TRiC), distantly related to Tcp1p and to Hsp60 Null mutant is inviable; overexpression suppresses a TOR2 dominant nagative allele
MEG1067 p-value 0.00363    
  Fly 0.53 (146) CBP 7238 IF4E eIF4E Eif4E Eif4e CG4035 eIF-4e CT13384 CT39424 CT39426 D-eIF4E 0589/11 l(3)07238 eIF-4E1,2 cap binding protein Eukaryotic initiation factor 4E eukaryotic initiation factor 4E
  Human 0.78 (561) eukaryotic translation initiation factor 4E EIF4E.EIF4F;EIF-4E;EIF4EL1.eukaryotic translation initiation factor 4E.
  Worm 0.30 (935) ife-3 B0348.6 Translation initiation factor eIF4E, binds to mRNA cap structure
  Yeast 0.46 (639) CDC33 Required for START A of cell cycle and sporulation mRNA cap binding protein eIF-4E Null mutant is inviable. cdc33 mutants arrest at G(sub)1. cdc33 has normal cAMP pools and is not suppressed by cAPK mutants, suggesting sporulation is independent of the cAMP pathway
MEG1798 p-value 0.00484    
  Fly 0.69 (150) No Name No Description
  Human 0.54 (772) methionine-tRNA synthetase MARS.METRS;MTRNS;MetRS.methionine-tRNA synthetase.
  Worm 0.44 (937) F58B3.5 Member of the tRNA synthetase, methionyl protein family
  Yeast 0.43 (639) ARC1 associated with tRNA and amino acyl-tRNA synthetases; has affinity for quadruplex nucleic acids Null mutant is viable, leads to slow growth and reduced MetRS activity; arc1- mutants are synthetic lethals and are complemented by the genes for methionyl-tRNA and glutamyl-tRNA synthetase.
MEG764 p-value 0.00605    
  Fly 0.64 (150) No Name No Description
  Human 0.68 (772) CYP2S1..hypothetical protein PTD004.
  Worm 0.59 (950) W08E3.3 Member of the GTP-binding protein family
  Yeast 0.28 (639) No Name No Description
MEG1851 p-value 0.00645    
  Fly 0.57 (150) No Name No Description
  Human 0.61 (772) seryl-tRNA synthetase SARS.SERS;SERRS.seryl-tRNA synthetase.
  Worm 0.45 (951) C47E12.1 Member of the tRNA synthetase, seryl protein family
  Yeast 0.45 (639) SES1 seryl-tRNA synthetase serine-tRNA ligase Null mutant is inviable.
MEG1831 p-value 0.00711    
  Fly 0.48 (150) mfl CG3333 minifly l(2)k05318 mfl: minifly
  Human 0.60 (772) dyskeratosis congenita 1, dyskerin DKC1.DKC;NAP57;NOLA4;XAP101;dyskerin.dyskerin.
  Worm 0.51 (945) K01G5.5 Possible ortholog of S. cerevisiae Cbf5p and D. melanogaster Nop60B nucleolar ribosomal processing proteins, possible ortholog of human DKC associated with X-linked dyskeratosis congenita
  Yeast 0.48 (639) CBF5 major low affinity 55 kDa Centromere/microtubule binding protein major low affinity 55 kDa centromere/microtubule binding protein Null mutant is inviable
MEG768 p-value 0.00764    
  Fly no data 39C10S CG11899 anon-sts29
  Human 0.10 (98) STRN3..phosphoserine aminotransferase isoform 2.
  Worm 0.44 (191) F26H9.5 Putative phosphoserine aminotransferase
  Yeast 0.71 (639) SER1 phosphoserine transaminase phosphoserine transaminase Null mutant is viable, serine-requiring
MEG2348 p-value 0.00798    
  Fly 0.76 (150) No Name No Description
  Human 0.55 (686) chaperonin containing TCP1, subunit 2 (beta) CCT2.CCTB;Cctb.chaperonin containing TCP1, subunit 2 (beta).
  Worm 0.47 (945) cct-2 T21B10.7 Member of the chaperonin complex protein family
  Yeast 0.21 (639) CCT2 cytoplasmic chaperonin of the Cct ring complex related to Tcp1p; subunit beta Null mutant is inviable; some mutant alleles exhibit defects in microtubule and actin assembly.
MEG2067 p-value 0.00888    
  Fly 0.46 (150) TRS P539 42/3 ThrRS CG5353 l(2)k04203 Threonyl-tRNA synthetase threonyl-tRNA synthetase
  Human 0.67 (772) C14orf66..hypothetical protein FLJ25005.
  Worm 0.50 (924) C47D12.6 Member of the tRNA synthetase, threonyl protein family
  Yeast 0.45 (639) THS1 Threonyl-tRNA synthetase, cytoplasmic threonine-tRNA ligase
MEG1587 p-value 0.00903    
  Fly 0.081 (150) VDAC Vdac POR-1 DmVDAC CG6647 l(2)k05123 Voltage-dependent anion-selective channel
  Human 0.84 (518) voltage-dependent anion channel 1 VDAC1.PORIN;PORIN-31-HL.voltage-dependent anion channel 1.
  Worm 0.64 (940) R05G6.7 Putative voltage-dependent anion-selective channel, has strong similarity to human and D. melanogaster voltage dependent anion channels porins
  Yeast 0.12 (639) POR2 Mitochondrial porin voltage dependent anion channel (YVDAC2) Null mutant is viable; omp2 por2 double null mutant shows poor growth; POR2 is a multicopy suppressor of omp2 null temperature-sensitive petite phenotype
MEG866 p-value 0.00927    
  Fly no data gart GART ADE8 Gart CG8761 CG31628 l(2)27Da Gart/ade3 Complementation group D
  Human 0.66 (1176) phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase GART.AIRS;GARS;PAIS;PGFT;PRGS;GARTF;MGC47764.phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase isoform 2.
  Worm 0.27 (909) F38B6.4 Putative GARSase plus AIRSase, bifunctional protein, putative ortholog S. cerevisiae Ade5.7p gene product
  Yeast 0.69 (639) ADE5,7 glycinamide ribotide synthetase and aminoimidazole ribotide synthetase aminoimidazole ribotide synthetase|glycinamide ribotide synthetase Adenine requiring
MEG4919 p-value 0.00953    
  Fly 0.64 (150) p42A CG5378
  Human 0.52 (772) FARP2.KIAA0107.KIAA0107 gene product.
  Worm 0.65 (942) F49C12.8 Member of the PCI domain protein family
MEG2009 p-value 0.0101    
  Fly 0.56 (150) delf eRF3 CG6382 Dsup35 dsup35
  Human 0.62 (1176) G1 to S phase transition 2 GSPT2.GST2;ERF3B;eRF3b;FLJ10441.peptide chain release factor 3.
  Worm 0.58 (940) H19N07.1 Member of the translation elongation factor EF1alpha-like protein family
  Yeast 0.35 (639) SUP35 altered form creates [PSI] prion translation termination factor eRF3 accumulation of large budded cells and substantial arrest of DNA synthesis at the nonpermissive temperature (arrests at G(sub)1/S transition); omnipotent suppressor of nonsense mutations
MEG747 p-value 0.0137    
  Fly 0.19 (150) M M57g M(4) RPS3A RPS3a RpS3a CG2168 M(4)101 Clone 3 M(4)57g clone 2.29 l(4)102ABa Minute(4)101 anon-EST:Liang-2.29 ribosomal protein S3 ribosomal protein S3a
  Human 0.79 (555) ribosomal protein S3A RPS3A.FTE1.ribosomal protein S3a.
  Worm 0.44 (923) F56F3.5 Member of the ribosomal protein S1 protein family
  Yeast 0.47 (639) RPS1A Homologous to rat S3A ribosomal protein S1A (rp10A)
MEG5471 p-value 0.0155    
  Fly no data No Name No Description
  Human 0.89 (417) complement component 1, q subcomponent binding protein C1QBP.p32;HABP1;gC1qR;GC1QBP;SF2p32;gC1Q-R.complement component 1, q subcomponent binding protein precursor.
  Worm 0.58 (917) F59A2.3 Protein of unknown function with moderate similarity to H. sapiens C1QBP gene product, pre-mRNA splicing factor SF2p32
MEG6042 p-value 0.0156    
  Fly 0.61 (150) p55 CG1100
  Human 0.72 (686) proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 PSMD12.p55.proteasome 26S non-ATPase subunit 12 isoform 2.
  Worm 0.59 (945) F10G7.8 Putative ortholog of S. cerevisiae Rpn5p, the non-ATPase subunit of the 26S proteasome complex
MEG588 p-value 0.0160    
  Fly 0.49 (150) No Name No Description
  Human 0.63 (772) chromosome 12 open reading frame 10 C12orf10.MYG;MYG1.MYG1 protein.
  Worm 0.58 (949) K08H10.8 Putative ortholog of S. cerevisiae Yer156p, a nonessential protein of unknown function
  Yeast 0.37 (639) No Name No Description
MEG443 p-value 0.0167    
  Fly no data No Name No Description
  Human 0.71 (686) lysyl-tRNA synthetase KARS.KIAA0070.lysyl-tRNA synthetase.
  Worm 0.62 (925) T02G5.9 Member of the lysyl tRNA synthetase protein family
  Yeast 0.45 (639) KRS1 lysyl-tRNA synthetase lysine-tRNA ligase Null mutant is inviable; mutants can show resistance to 5-methyltryptophan, 5-fluorotryptophan and canavanine; constitutive derepression and slow growth; posttranscriptional increase in histidine biosynthetic enzyme activity
MEG898 p-value 0.0170    
  Fly 0.59 (150) dmLa D-La 38C.38 CG10922 DLa/SS-B BEST:LD24519 ribonucleoprotein La
  Human 0.75 (772) Sjogren syndrome antigen B (autoantigen La) SSB..autoantigen La.
  Worm 0.41 (926) C44E4.4 Putative RNA-binding protein with moderate similarity to D. melanogaster LA La autoantigen-like RNA-binding protein
  Yeast 0.36 (639) LHP1 Protein homologous to human La (SS-B) autoantigen Null mutant is viable
MEG841 p-value 0.0178    
  Fly 0.54 (150) MAP2 DMAP2 CG4008
  Human 0.78 (772) methionyl aminopeptidase 2 METAP2.p67;MNPEP.methionyl aminopeptidase 2.Similar to rat initiation factor 2 (EIF-2) binding protein; has cobalt-dependent methionine aminopeptidase activity|Proteome
  Worm 0.33 (933) Y116A8A.9 Putative ortholog of C. elegans F53B6.5 gene product
  Yeast 0.13 (639) MAP2 methionine aminopeptidase 2 methionine aminopeptidase 2 Null mutant is viable, map1 map2 double null mutant is inviable
MEG4714 p-value 0.0180    
  Fly 0.59 (126) No Name No Description
  Human 0.38 (199) signal recognition particle 14kDa (homologous Alu RNA binding protein) SRP14.ALURBP.signal recognition particle 14kDa (homologous Alu RNA binding protein).
  Worm 0.32 (944) F25G6.8 Protein with similarity to H. sapiens SRP14 gene product, the 14kD subunit of signal recognition particle Alu RNA-binding protein
MEG1486 p-value 0.0196    
  Fly 0.60 (150) CG11716 anon-EST:fe2B6 anon-fast-evolving-2B6
  Human 0.61 (772) zinc finger protein 9 (a cellular retroviral nucleic acid binding protein) ZNF9.DM2;CNBP;CNBP1.zinc finger protein 9.
  Worm no data K08D12.3 Protein with strong similarity to C. elegans glh-2 gene product
  Yeast 0.46 (639) GIS2 GIG3 suppressor
MEG397 p-value 0.0201    
  Fly 0.43 (150) ERS AATS GluRS CG5394 Aats-glu GluProRS GluPro-RS AATs-GluPro Aa-tRNA-syn-glupro Glutamyl-tRNA synthetase aminoacyl-tRNA synthetase glutamyl-prolyl-tRA synthetase glutamyl-prolyl-tRNA synthetase
  Human 0.48 (772) glutamyl-prolyl-tRNA synthetase EPRS.PARS;QARS;QPRS.glutamyl-prolyl tRNA synthetase.
  Worm 0.62 (935) T20H4.3 Putative glutamyl-prolyl-tRNA synthetase
  Yeast 0.39 (639) No Name No Description
MEG6071 p-value 0.0204    
  Fly 0.45 (150) CG10161 eIF3-S7 GM10514 GM04979 BEST:GM10514 Eukaryotic initiation factor 3 p66 subunit
  Human 0.76 (99) eukaryotic translation initiation factor 3, subunit 7 zeta, 66/67kDa EIF3S7.MGC17258;eIF3-p66;eIF3-zeta.eukaryotic translation initiation factor 3 subunit 7.
  Worm 0.54 (951) R08D7.3 Putative eukaryotic translation initiation factor 3 that is expressed in 4 head ganglia late during embryogeneis
MEG2287 p-value 0.0218    
  Fly 0.75 (150) T-cpl Tcp-1 CG5374
  Human no data t-complex 1 TCP1.CCT1;Ccta;D6S230E.t-complex 1.
  Worm 0.43 (943) cct-1 T05C12.7 Member of the chaperonin complex protein family
  Yeast 0.41 (639) TCP1 tailless complex polypeptide 1 chaperonin subunit alpha Null mutant is inviable
MEG924 p-value 0.0219    
  Fly no data No Name No Description
  Human 0.71 (686) phenylalanine-tRNA synthetase-like FARSL.FRSA;CML33;PheHA.phenylalanine-tRNA synthetase-like protein.
  Worm 0.68 (188) T08B2.9 Putative beta subunit of phenylalanyl-tRNA synthetase
  Yeast 0.38 (639) FRS2 Phenylalanyl-tRNA synthetase, beta subunit, cytoplasmic phenylalanine-tRNA ligase subunit
MEG1076 p-value 0.0225    
  Fly no data CG10687
  Human 0.23 (199) asparaginyl-tRNA synthetase NARS.ASNRS.asparaginyl-tRNA synthetase.
  Worm 0.71 (936) F22D6.3 Member of the tRNA synthetase, aspartyl-asparaginyl protein family
  Yeast 0.46 (639) DED81 Asparaginyl-tRNA synthetase asparaginyl-tRNA synthetase
MEG517 p-value 0.0225    
  Fly no data No Name No Description
  Human 0.36 (1176) serine hydroxymethyltransferase 1 (soluble) SHMT1.CSHMT;MGC15229;MGC24556.serine hydroxymethyltransferase 1 (soluble) isoform 2.
  Worm 0.56 (936) mel-32 C05D11.11 Putative serine hydroxymethyltransferase
  Yeast 0.67 (639) SHM2 serine hydroxymethyltransferase Null mutant is viable
MEG1966 p-value 0.0268    
  Fly 0.48 (150) Ran dran CG1404 ran10A
  Human 0.48 (1176) RAN, member RAS oncogene family RAN.TC4;ARA24.ras-related nuclear protein.
  Worm 0.52 (948) K01G5.4 Ran, GTP-binding protein of the ras superfamily possibly involved in trafficking through the nuclear pore putative ortholog of S. cerevisiae Gsp1p and Gsp2p and putative ortholog of human androgen receptor associated protein ARA24
  Yeast 0.46 (639) GSP1 maintenance of nuclear organization; homologous to mammalian Ran, a small nuclear GTPase of the ras superfamily GTP-binding protein Null mutant is inviable
MEG2208 p-value 0.0275    
  Fly 0.42 (150) CG8288 mitochondrial ribosomal protein L3
  Human 0.76 (772) mitochondrial ribosomal protein L3 MRPL3.MRL3;RPML3.mitochondrial ribosomal protein L3.
  Worm 0.65 (941) C26E6.6 Protein with weak similarity to ribosomal protein L3
  Yeast 0.055 (639) MRPL9 Mitochondrial ribosomal protein MRPL9 (YmL9) (E. coli L3) (human MRL3) ribosomal protein (YmL9) (E. coli L3) (human MRL3) Null mutant is viable
MEG1396 p-value 0.0276    
  Fly 0.43 (150) IRS IleRS CG11471 l(3)00827 Isoleucyl-tRNA synthetase
  Human 0.79 (595) isoleucine-tRNA synthetase IARS.ILRS.isoleucine-tRNA synthetase.
  Worm 0.55 (939) R11A8.6 Member of the tRNA synthetase, isoleucyl protein family
  Yeast 0.22 (639) ILS1 cytoplasmic isoleucyl-tRNA synthetase isoleucine-tRNA synthetase Arrests in early G1 at nonpermissive temperature of 36 degrees C
MEG2118 p-value 0.0337    
  Fly 0.55 (150) MCM6 DmMCM6 CG4039 fs(1)K1214 female sterile(1)K1214 Minichromosome maintenance 6
  Human 0.79 (772) MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) MCM6..MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe).
  Worm 0.34 (945) ZK632.1 Member of the MCM initiator complex DNA replication protein family
  Yeast 0.20 (639) MCM6 Member of the MCM/P1 family of proteins involved in DNA replication Null mutant is inviable.
MEG328 p-value 0.0343    
  Fly no data ral UMPS OPRT OMPDC CG3593 UMP synthase orotidine phosphate decarboxylase
  Human 0.65 (1090) uridine monophosphate synthetase (orotate phosphoribosyl transferase and orotidine-5'-decarboxylase) UMPS.OPRT.uridine monophosphate synthetase (orotate phosphoribosyl transferase and orotidine-5-decarboxylase).
  Worm 0.65 (748) R12E2.11 Member of the orotate phosphoribosyltransferase protein family
  Yeast 0.44 (639) URA5 Fifth step in pyrimidine biosynthesis pathway orotate phosphoribosyltransferase 1 Null mutant is viable
MEG914 p-value 0.0351    
  Fly 0.12 (146) CG17273
  Human 0.36 (999) adenylosuccinate synthase like 1 ADSSL1.FLJ38602.hypothetical protein FLJ38602.
  Worm 0.18 (940) C37H5.6 Member of the adenylosuccinate synthetase protein family
  Yeast 0.75 (639) ADE12 adenylosuccinate synthetase adenylosuccinate synthetase Adenine requiring
MEG461 p-value 0.0370    
  Fly 0.083 (150) IMPDH CG1799 LD06825 l(1)9Eb LD02673 CG11485 EP(X)1093 raspberry/impd raspberry-lethal IMP dehydrogenase ras-l: raspberry-lethal inosine monophosphate dehydrogenase
  Human 0.64 (1090) IMP (inosine monophosphate) dehydrogenase 1 IMPDH1.IMPD;IMPD1.IMP (inosine monophosphate) dehydrogenase 1.
  Worm 0.64 (940) T22D1.3 Member of the inosine-5 -monophosphate dehydrogenase protein family
  Yeast 0.43 (639) IMD3 IMP dehydrogenase homolog IMP dehydrogenase homolog
MEG2178 p-value 0.0390    
  Fly 0.64 (150) Tik CK2 CK2a CK-2 CKII CkII CK II CK-II CKIIa DmCKII CK-II CG17520 CK2 alpha CKIIalpha Cask-II-a Timekeeper NAP1-kinase Casein kinase II
  Human 0.72 (594) casein kinase 2, alpha 1 polypeptide CSNK2A1.CKII;CK2A1.casein kinase II alpha 1 subunit isoform b.
  Worm 0.23 (949) B0205.7 CKIIalpha Casein kinase II, alpha subunit
  Yeast 0.36 (639) CKA1 alpha subunit of protein kinase CK2 protein kinase CK2 alpha subunit Null mutant is viable; however, strains lacking both cka1 and cka2 (the alpha and alpha' subunits of protein kinase CK2, respectively) are inviable.
MEG122 p-value 0.0406    
  Fly 0.13 (150) SamS METK Sam-S CG2674 Su(z)5 M(2)21A-B S-Adenosylmethionine synthetase Methionine adenosyl transferase S-adenosylmethionine synthetase SamS: S-adenosylmethionine synthetase
  Human 0.42 (1176) methionine adenosyltransferase I, alpha MAT1A.MAT;SAMS;MATA1;SAMS1.methionine adenosyltransferase I, alpha.
  Worm 0.58 (944) C06E7.1 Member of the s-adenosylmethionine synthetase protein family
  Yeast 0.51 (639) SAM2 methionine biosynthesis regulation Null mutant is viable
MEG1598 p-value 0.0413    
  Fly no data DrOST OST48 CG9022 DmOST50 OST48/WBP1
  Human 0.64 (772) dolichyl-diphosphooligosaccharide-protein glycosyltransferase DDOST.OST;OST48;KIAA0115.dolichyl-diphosphooligosaccharide-protein glycosyltransferase.
  Worm 0.61 (946) T09A5.11 Putative subunit of oligosaccharyltransferase dolichyl-diphosphooligosaccharide-protein glycosyltransferase , possible ortholog of human DDOST protein Hs.89674
  Yeast 0.38 (639) WBP1 wheat germ agglutinin-binding protein oligosaccharyl transferase glycoprotein complex, beta subunit lethal
MEG1370 p-value 0.0423    
  Fly 0.45 (150) RACK1 rack1 CG7111
  Human 0.69 (772) guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 GNB2L1.H12.3;RACK1;Gnb2-rs1.guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1.
  Worm 0.41 (953) K04D7.1 Member of the WD repeat protein family
  Yeast 0.41 (584) ASC1 WD repeat protein (G-beta like protein) that interacts with the translational machinery G-beta like protein Null mutant is viable. Null mutation suppresses the absence of growth of a cyp1- strain in anaerobiosis and also causes delayed growth in aerobic or heme sufficient conditions; trp auxotrophs of the asc1 null allele are cold sensitive for growth; other mutants have increased cell size
MEG1087 p-value 0.0444    
  Fly 0.29 (150) Pros1 CG18495 20S proteasome 20S proteasome subunit alpha1
  Human 0.75 (772) proteasome (prosome, macropain) subunit, alpha type, 6 PSMA6.IOTA;p27K;PROS27;MGC2333;MGC22756;MGC23846.proteasome alpha 6 subunit.
  Worm 0.66 (948) C15H11.7 Member of the proteasome subunit protein family
  Yeast 0.094 (639) SCL1 Proteasome subunit YC7alpha/Y8 (protease yscE subunit 7) proteasome subunit YC7alpha/Y8 (protease yscE subunit 7) Null mutant is inviable, SCL1 is a dominant suppressor of the ts lethality of crl3
MEG153 p-value 0.0472    
  Fly no data elF2 Eif2 IF2B eIF2 eIF-2 D-eIF2 CG4153
  Human 0.66 (772) eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa EIF2S2.EIF2;EIF2B;MGC8508;EIF2beta.eukaryotic translation initiation factor 2 beta.
  Worm 0.58 (926) K04G2.1 Putative translational initiation factor 2, beta subunit, has strong similarity to human EIF2S2 protein
  Yeast 0.47 (639) SUI3 eIF2 is a heterotrimeric GTP-binding protein <br> SUI2 encodes the alpha subunit<br> GCD11 encodes the gamma subunit translation initiation factor eIF-2 beta subunit suppression of initiator codon mutations