Supplemental Table 4.  Precision of multi-species network on cell proliferation compared to single species.

 

No. Cell Cyclea

Multi

Fly

Human

Worm

Yeast

 

Meta-geneb

Nbrsc

Gene

Nbrsd

Genee

Nbrs

Gene

Nbrs

Gene

Nbrs

2

MEG1503

10

FBGN0000426

 

6636

7

ZK652.1

67

YPR182W

7

14

MEG342

34

FBGN0038274

102

9688

44

Y37E3.15A

 

YFR002W

237

1

MEG4513

1

FBGN0031769

2

55920

2

 

 

 

 

6

MEG1192

29

FBGN0035420

41

9703

68

F31C3.3

33

YPR117W

50

6

MEG1146

17

FBGN0037659

178

22992

185

F29B9.2A

50

YER051W

28

 

 

 

 

 

23133

106

T26A5.5A

67

 

 

 

aThe number of cell proliferation / cell cycle links the meta-gene has in the multi-species network.

bOne of the five meta-genes predicted to be involved in cell proliferation.

cThe number of total links the meta-gene has in the multi-species expression network.

dThe number of links required to get as many cell proliferation / cell cycle links as in the multi-species network.  This number was obtained by ranking all of the genes based on their Pearson correlations to the central gene and then including this many genes to capture the same number of cell cycle genes as in the multi-species network.  An empty cell indicates either the meta-gene does not have an ortholog or does not have data in the particular organism.

eLocusLink identifier.  Note that two human genes belong to meta-gene MEG1146.