Supplemental Table 5. Conservation of expression linksa.

Meta-gene

Protein

Yeastb

Worm

Fly

Human

ECIc

MEG2054

S7 ribosomal protein

10.9

5.7

11.4

15.0

10.7

MEG2114

S14 ribosomal protein

9.0

4.6

17.4

7.0

9.51

MEG747

S3 ribosomal protein

8.7

5.5

9.0

14.6

9.45

MEG573

RER1 protein trafficking

n/ad

0.7

0.3

25.0

8.68

MEG418

NOP5A ribosome assembly

8.2

4.3

6.5

14.0

8.25

MEG829

mRNA turnover

6.9

4.6

7.5

13.6

8.13

MEG73

L37 ribosomal protein

7.0

n/a

10.7

6.5

8.06

MEG1996

S29 ribosomal protein

6.3

3.4

15.1

7.4

8.03

MEG1688

NOP4 ribosome assembly

7.7

5.0

6.2

12.0

7.72

MEG1831

NOP60B ribosome assembly

7.5

3.8

6.4

12.4

7.51

MEG898

LA La autoantigen-like RNA-binding protein

7.9

4.2

5.6

12.3

7.49

MEG120

P0 ribosomal protein

8.7

3.6

6.6

10.7

7.42

MEG959

alanine aminotransferase

8.3

5.7

5.9

9.5

7.35

MEG1854

actin dependent chromatin regulator

n/a

0.3

0.3

21.4

7.34

MEG1370

RACK1

8.7

3.8

6.0

10.6

7.27

MEG1259

L30 ribosomal protein

8.1

6.0

6.6

8.3

7.23

MEG1183

L12 ribosomal protein

9.4

4.9

6.2

8.3

7.21

MEG2056

L18 ribosomal protein

8.8

3.8

6.3

9.7

7.14

MEG1116

Peter pan

6.7

6.7

4.5

10.3

7.05

MEG253

S0 ribosomal protein

7.2

3.5

6.5

10.9

7.03

aThe top 20 meta-genes with the highest ECIs.

bThe percent of expression links present in the organism that are also present in the multiple species network.

cThe expression conservation index as described in the paper (for a single meta-gene, this is the average across the organisms).

dn/d indicates the meta-gene did not have an ortholog (or had no data) in this organism.