Gene putatively regulated by attenuation in S_pneumoniae_R6

This operon is putativelly rgulated by Riboflavin_riboswitch

                                                                        Characteristics of the secondary structures
Terminator:    Distance from promoter:211 nt.    Distance to gene:13 nt.     Distance to run of Ts=0 nt.   Size=34 nt.     Delta G=-18.40 kcal/mol

                                                                        Nomenclature/Definitions
The most likely promoter is: ttgaca-tataat. It has a score value of 97.72 and is shown in blue

ttgacatattcaaaattaagtactataatcatctgtaattgaataactatcttcagggcagggtgcaattccctaccggtggtatagcccacgagccgaa
aggcatgatttggtgaaattccaaagccgacagtatagtctggatgaaagaagataaaagtatatttgtgctttttgcgtgctctgaaatgattacttgt
catttcagagcatttttgttaatcgcataagttttcttttgtatgccttgagtagtcccctattcaaggtatattttttggaggtagtgagATG

    ribD --- ribC --- ribA --- ribE


Gene: ribD     GI: 15902208     BI number: spr0164     GOG: COG0117,COG1985     Description: Riboflavin biosynthese; a deaminase
Gene: ribC     GI: 15902207     BI number: spr0163     GOG: COG0307     Description: Riboflavin synthase alpha-chain
Gene: ribA     GI: 15902206     BI number: spr0162     GOG: COG0108,COG0807     Description: Riboflavin biosynthesis; GTP-cyclohydrolase II.
Gene: ribE     GI: 15902205     BI number: spr0161     GOG: COG0054     Description: Riboflavin synthase beta chai


          cc
         t  c
          gc
          at
          ta
          gt
          at
          gc
          ta
          ta
          cg
          cg
          gt
          ta
          at
          ta
          gt
            tttttggaggtagtgagATG


                                                                        Orthologous genes that have a predicted attenuator, grouped in COG families

[H] COG0117 Pyrimidine deaminase ... can be seen here
[H] COG1985 Pyrimidine reductase, riboflavin biosynthesis ... can be seen here
[H] COG0307 Riboflavin synthase alpha chain ... can be seen here
[H] COG0108 3,4-dihydroxy-2-butanone 4-phosphate synthase ... can be seen here
[H] COG0807 GTP cyclohydrolase II ... can be seen here
[H] COG0054 Riboflavin synthase beta-chain ... can be seen here

                                                                        Genes that have a predicted attenuator with a riboswitch:

Riboflavin_riboswitch sequence ... can be seen here

    ..................................................................................................................


                                                                        Gene putatively regulated by attenuation in S_pneumoniae_R6

This operon is putativelly rgulated by Riboflavin_riboswitch

                                                                        Characteristics of the secondary structures
Terminator:    Distance from promoter:149 nt.    Distance to gene:73 nt.     Distance to run of Ts=0 nt.   Size=35 nt.     Delta G=-21.50 kcal/mol

                                                                        Nomenclature/Definitions
The most likely promoter is: ttgaca-tataat. It has a score value of 97.72 and is shown in blue

ttgacatattcaaaattaagtactataatcatctgtaattgaataactatcttcagggcagggtgcaattccctaccggtggtatagcccacgagccgaa
aggcatgatttggtgaaattccaaagccgacagtatagtctggatgaaagaagataaaagtatatttgtgctttttgcgtgctctgaaatgattacttgt
catttcagagcatttttgttaatcgcataagttttcttttgtatgccttgagtagtcccctattcaaggtatattttttggaggtagtgagATG

    ribD --- ribC --- ribA --- ribE


Gene: ribD     GI: 15902208     BI number: spr0164     GOG: COG0117,COG1985     Description: Riboflavin biosynthese; a deaminase
Gene: ribC     GI: 15902207     BI number: spr0163     GOG: COG0307     Description: Riboflavin synthase alpha-chain
Gene: ribA     GI: 15902206     BI number: spr0162     GOG: COG0108,COG0807     Description: Riboflavin biosynthesis; GTP-cyclohydrolase II.
Gene: ribE     GI: 15902205     BI number: spr0161     GOG: COG0054     Description: Riboflavin synthase beta chai


           c
         a  t
         t  t
          tg
          at
          gc
          ta
          at
          at
          at
          gc
          ta
          cg
          ta
          cg
          gc
          ta
          gt
            ttttgttaatcgcataagttttcttttgtatgccttgagtagtcccctattcaaggtatattttttggaggtagtgagATG


                                                                        Orthologous genes that have a predicted attenuator, grouped in COG families

[H] COG0117 Pyrimidine deaminase ... can be seen here
[H] COG1985 Pyrimidine reductase, riboflavin biosynthesis ... can be seen here
[H] COG0307 Riboflavin synthase alpha chain ... can be seen here
[H] COG0108 3,4-dihydroxy-2-butanone 4-phosphate synthase ... can be seen here
[H] COG0807 GTP cyclohydrolase II ... can be seen here
[H] COG0054 Riboflavin synthase beta-chain ... can be seen here

                                                                        Genes that have a predicted attenuator with a riboswitch:

Riboflavin_riboswitch sequence ... can be seen here

    ..................................................................................................................