Recent Publications

Chi, T.H. and G.R. Crabtree. Inositol phosphates in the nucleus. Science 287:1937-1939, 2000.

Biggar, S.R. and G.R. Crabtree. Chemically regulated transcription factors reveal persistence of repressor-resistant transcription after disrupting activator function. J. Biol Chem. 275:25381-90, Aug 2000.

Stewart, S. and G.R. Crabtree. Transcription. Regulation of the regulators. Nature 408: 46-7, 2000.

Rose, R.B., J.H. Bayle, J.A. Endrizzi, J.D. Cronk. G.R. Crabtree, and T. Albert. Structural basis of dimerization, coactivator recognition and MODY3 mutations in HNF-1 alpha. Nat Struct Biol. Vol. 9:744-8, Sept 2000.

Wulfing, C., A. Bauch, G.R. Crabtree, and M.M Davis,. The vav exchange factor is an essential regulator in actin-dependent receptor translocation to the lymphocyte-antigen-presenting cell interface. Proc Natl Acad Sci U S A. 97:10150-5, 2000 Aug 29.

Rando, O.J., K. Zhao, and G.R. Crabtree. Searching for a function for nuclear actin. Trends Cell Biol. 2000 Mar;10(3):92-7.

Crabtree, G.R. Calcium, Calcineurin, and the Control of Transcription. J Biol Chem. 2001 Jan 26;276(4):2313-2316.

Bultman, S., T. Gebuhr, D. Yee, C. La Mantia, J. Nicholson, A. Gilliam, F. Randazzo, D. Metzger, P. Chambon, G. Crabtree, and T. Magnuson. A Brg1 null mutation in the mouse reveals functional differences among mammalian SWI/SNF complexes.Mol Cell. 2000 Dec;6(6):1287-95.

Behrens, A., K. Sabapathy, I. Graef, M. Cleary, G.R. Crabtree, and E.F. Wagner. Jun N-terminal kinase 2 modulates thymocyte apoptosis and T cell activation through c-Jun and nuclear factor of activated T cell (NF-AT). Proc Natl Acad Sci U S A. 2001 Feb 13;98(4):1769-1774.

Vogel, K.W., R. Briesewitz, T. J. Wandless, and G.R. Crabtree. Calcineurin inhibitors and the generalization of the presenting protein strategy. Adv Protein Chem. 2001;56:253-91.

Graef, I.A., J.M. Gastier, U. Francke, and G.R. Crabtree. Evolutionary relationships among Rel domains indicate functional diversification by recombination. Proc Natl Acad Sci U SA. 2001 May 8;98(10):5740-5.

Biggar, S.R. and G.R. Crabtree. Cell signaling can direct either binary or graded transcriptional responses. Cell signaling can direct either binary or graded transcriptional responses. EMBO J. 2001 Jun 15;20(12):3167-76.

Graef I.A., F. Chen, L. Chen, A. Kuo, and G.R. Crabtree. Signals Transduced by

Calcineurin and NF.AT C3/C4 Pattern the Developing Vasculature. Cell 2001 Jun 29;105(7):863-75.