The data below represents gene expression profiling data obtained with
cDNA microarrays and is supplemental to data in the manuscript titled above.
Cells from 3 unrelated JEB patients were transduced with retroviral vectors
encoding GFP (JEB[-]), LAMB3 (JEB[+]), or grown on ECM containing laminin
5 (JEB[-] ECM). Normal human keratinocytes were cultured in parallel and
used as a reference standard. 21-28 days post-transduction, total cellular
RNA was extracted from each cell population and used to generate cDNA probes
for microarray hybridization. Labeled probes were incubated with one of
three Atlas array membranes (Clontech): Human Cancer 1.2, Human 1.2 or Human
1.2 II and the resultant hybridization signals were detected using a Molecular
Dynamics Storm 820 phosphorimager. Values are expressed as a percentage
of the average value measured for the same gene in triplicate normal controls
(Normal is arbitrarily assigned a value of 100%). The following list is
compiled from all of our experiments and represents every gene for which
at least one clear hybridization signal was detected. These gene expression
data are presented for comparison only and due to experimental variability,
may contain artifacts or spurious values for samples defined by a single
hybridization signal. A less comprehensive, but more accurate reflection
of the alterations in gene expression under the proscribed conditions can
be found in Table 3 (Robbins et al., submitted). The data presented in Table
3 are exclusively comprised of values for which 2-6 experimental replicates
were averaged and therefore, are less influenced by the experimental error
that can characterize this technique.
| Gene Name |
GenBank Accession #(s) |
JEB[-] |
JEB[+] |
JEB[-] ECM |
| 14-3-3 protein beta/alpha; protein kinase C inhibitor protein-1 (KCIP-1);
protein 1054 |
X57346 |
155 |
130 |
167 |
| 14-3-3 protein sigma; stratifin; epithelial cell marker protein 1 |
P31947 |
88 |
62 |
99 |
| 14-3-3 protein tau; 14-3-3 protein theta; 14-3-3 protein T-cell; HS1 protein |
X56468 |
94 |
56 |
79 |
| 14-3-3 PROTEIN ZETA/DELTA (PROTEIN KINASE C INHIBITOR PROTEIN-1) (KCIP-1)
(FACTOR ACTIVATING EXOENZYME S) (FAS). |
M86400 |
134 |
83 |
147 |
| 40S ribosomal protein S16 |
M60854 |
86 |
150 |
139 |
| 80-kDa nuclear cap-binding protein |
D32002 |
88 |
297 |
151 |
| acidic fibroblast growth factor (AFGF) + heparin-binding growth factor 1
precursor (HBGF-1) + beta-endothelial cell growth factor (ECGF-beta) |
P05230; P07502 |
84 |
110 |
75 |
| acute myeloid leukemia 1 protein; oncogene aml-1 |
D43967 |
106 |
273 |
118 |
| ADP/ATP carrier protein |
J02683 |
98 |
121 |
135 |
| AF-17 protein |
U07932 |
132 |
167 |
144 |
| alcohol dehydrogenase 6 + aldehyde dehydrogenase 1 (ALDH1) |
K03000 |
103 |
192 |
122 |
| aldehyde dehydrogenase (ALDH6) |
U07919 |
130 |
99 |
164 |
| alpha-1-acid glycoprotein 1 precursor (AGP1); orosomucoid 1 (OMD1) |
X02544 |
186 |
135 |
114 |
| alpha-2-antiplasmin |
D00174 |
134 |
82 |
146 |
| alpha-actinin 1 cytoskeletal isoform; F-actin cross linking protein |
X15804 |
122 |
86 |
126 |
| alpha-catenin related protein (CAPR); alpha 2 catenin (CTNNA2); alpha N-catenin |
P26232 |
77 |
84 |
58 |
| alpha-galactosidase A precursor; melibiase; alpha-D-galactoside galactohydrolase |
X05790 |
176 |
95 |
153 |
| alpha1 catenin (CTNNA1); cadherin-associated protein; alpha E-catenin |
P35221 |
100 |
97 |
90 |
| Alzheimer's disease amyloid A4 protein precursor; protease nexin-II (PN-II);
APPI |
Y00264 |
174 |
116 |
220 |
| annexin I (ANX1) |
X05908 |
90 |
72 |
90 |
| annexin II (ANX2); lipocortin II; calpactin I heavy subunit; chromobindin
8; protein I; placental anticoagulant protein IV (PAPIV) |
D00017 |
81 |
79 |
96 |
| annexin III (ANX3); lipocortin III; placental anticoagulant protein III)
(PAP-III); 35-alpha calcimedin; inositol 1,2-cyclic phosphate 2-phosphohydrolase |
M20560; J03899 |
124 |
96 |
139 |
| annexin IV (ANX4); lipocortin I; calpactin II; chromobindin 9; phospholipase
A2 inhibitory protein |
X05908; M19383; J03264 |
113 |
94 |
122 |
| annexin IV (ANX4); lipocortin IV; endonexin I; chromobindin 4; protein II;
placental anticoagulant protein II (PAP-II); PP4-X; 35-beta calcimedin;
carbohydrate-binding protein p33/p41 |
M19383 |
135 |
87 |
143 |
| annexin V; lipocortin V; endonexin II; calphobindin I (CBP-I) ; placental
anticoagulant protein I (PAP-I); PP4; thromboplastin inhibitor; vascular
anticoagulant-alpha (VAC-alpha; anchorin CII |
X12454 |
126 |
108 |
148 |
| annexin VI (ANX6); lipocortin VI; protein III; chromobindin 20; 67-kDa calelectrin;
calphobindin-II (CPB-II) |
D00510 |
146 |
93 |
144 |
| annexin VII (ANX7); synexin |
J04543 |
87 |
59 |
79 |
| annexin VIII (ANX8) |
X16662 |
122 |
89 |
124 |
| ANNEXIN XI (CALCYCLIN-ASSOCIATED ANNEXIN 50) (CAP-50) (56 KD AUTOANTIGEN). |
L19605 |
131 |
90 |
137 |
| ANNEXIN XIII (ANNEXIN, INTESTINE-SPECIFIC)(ISA) |
Z11502 |
91 |
84 |
124 |
| antileukoproteinase 1 precursor (ALP); HUSI-1; seminal proteinase inhibitor;
secretory leukocyte protease inhibitor (SLPI); BLPI; mucus proteinase inhibitor
(MPI) |
X04470 |
162 |
57 |
120 |
| apolipoprotein E precursor (APOE) |
M12529 |
229 |
129 |
242 |
| apoptosis inhibitor survivin |
U75285 |
45 |
87 |
44 |
| arylsulfatase B precursor (ASB); N-acetylgalactosamine-4-sulfatase (G4S) |
J05225 |
144 |
107 |
155 |
| basigin precursor (BSG); leukocyte activation antigen M6; collagenase stimulatory
factor; extracellular matrix metalloproteinase inducer (EMMPRIN); 5F7; CD147
antigen |
P35613 |
84 |
129 |
103 |
| beta 3-endonexin |
Q13352 |
72 |
57 |
67 |
| beta catenin (CTNNB) |
P35222 |
87 |
112 |
78 |
| bikunin; hepatocyte growth factor activator inhibitor 2 |
O00271; O43291 |
94 |
109 |
82 |
| bone morphogenetic protein type IB receptor (BMPR1B) |
U89326 |
133 |
167 |
168 |
| brain-specific homeobox/POU domain protein 5 (brn-5) |
Z21966 |
102 |
146 |
123 |
| c-myc purine-binding transcription factor puf; nucleoside diphosphate kinase
B (NDP kinase B; NDK B) + nm23-H2S |
L16785 + M36981 |
64 |
122 |
172 |
| cadherin 11 precursor (CDH11); osteoblast-cadherin (OB-cadherin); OSF4 |
P55287; Q15065 |
123 |
123 |
70 |
| cadherin 12 (CDH12); brain cadherin precursor (Br-cadherin); neural cadherin
2 (N-cadherin 2) |
P55289 |
65 |
68 |
50 |
| cadherin 13 (CDH13); truncated cadherin precursor (T-cadherin); heart cadherin
(H-cadherin) |
P55290 |
81 |
78 |
63 |
| cadherin 3 (CDH3); placental cadherin precursor (P-cadherin; CDHP) |
P22223 |
167 |
148 |
92 |
| cadherin 4 (CDH4); retinal cadherin precursor (R-cadherin; RCAD) |
P55283 |
100 |
96 |
72 |
| cadherin 5 (CDH5); vascular endothelial cadherin precursor (VE-cadherin);
7B4 antigen; CD144 antigen |
P33151 |
160 |
146 |
76 |
| cadherin 6 precursor (CDH6); kidney cadherin (K-cadherin) |
P55285 |
83 |
73 |
57 |
| cadherin 8 (CDH8) |
P55286 |
97 |
79 |
47 |
| cadherin1 (CDH1); epithelial cadherin precursor (E-cadherin; CDHE); uvomorulin
(UVO); CAM 120/80 |
P12830; Q14216 |
103 |
176 |
71 |
| calcium-binding protein p22; calcium-binding protein CHP |
U61538 |
140 |
83 |
143 |
| calcium-dependent protease small (regulatory) subunit; calpain; calcium-activated
neutral proteinase (CANP) |
X04106 |
147 |
96 |
153 |
| calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A
(CAM-PDE1A); HCAM-1 |
U40370 |
139 |
102 |
113 |
| calcium/calmodulin-dependent protein kinase I (CAMKI) |
L41816 |
55 |
77 |
73 |
| calgranulin C (CAGC) CGRP; neutrophil S100 protein; calcium-binding protein
in amniotic fluid 1 (CAAF1) |
X97859 |
199 |
116 |
193 |
| calmodulin |
M27319 |
145 |
90 |
146 |
| calmodulin |
J04046 |
135 |
96 |
144 |
| calmodulin 1; delta phosphorylase kinase |
P02593 |
83 |
92 |
114 |
| calpactin I light chain |
M81457 |
120 |
98 |
133 |
| calpain 1 large (catalytic) subunit; mu-type calcium-activated neutral proteinase
(muCANP) |
X04366 |
127 |
84 |
132 |
| calpain 2 large (catalytic) subunit; M-type calcium-activated neutral proteinase
(CANP) |
M23254 |
133 |
88 |
143 |
| calpain p94 large (catalytic) subunit; calcium-activated neutral proteinase
(CANP); muscle-specific calcium-activated neutral protease 3 large subunit
(CAPN3); NCL1 |
X85030 |
109 |
57 |
75 |
| caltractin 1 (CALT); centrin 2 (CETN2; CEN2) |
X72964 |
88 |
81 |
114 |
| cannabinoid receptor 1 (CB1; CB-R); CANN6 |
X81120 |
140 |
102 |
158 |
| cartilage matrix protein (CMP; CRTM); matrilin 1 (MATN1) |
M55682; J05666 |
107 |
143 |
312 |
| casein kinase I alpha isoform (CKI-alpha); CK1; CSNK1A |
X80693 |
131 |
92 |
132 |
| casein kinase I delta isoform (CKI-delta); CSNK1D |
U29171 |
125 |
89 |
138 |
| casein kinase I gamma 2 (CKI-gamma 2) |
P78368 |
101 |
129 |
83 |
| casein kinase II alpha subunit (CK II); CSNK2A1 |
J02853 |
104 |
73 |
116 |
| casein kinase II alpha' subunit (CK II); CSNK2A2 |
M55268 |
135 |
89 |
137 |
| casein kinase II beta subunit (CK II; CSNK2B; CK2N); phosvitin |
X16937 |
146 |
108 |
159 |
| cathepsin B precursor (CTSB); preprocathepsin B; APP secretase |
M14221 |
159 |
99 |
159 |
| cathepsin D precursor (CTSD) |
P07339 |
128 |
88 |
103 |
| CATHEPSIN G PRECURSOR |
M16117 |
195 |
123 |
199 |
| cathepsin H precursor |
X07549 |
134 |
94 |
127 |
| cathepsin L precursor; major excreted protein (MEP) |
X12451 |
72 |
106 |
70 |
| caveolin-1 |
Q03135 |
75 |
86 |
93 |
| caveolin-2 |
P51636 |
80 |
107 |
77 |
| CCAAT/enhancer binding protein gamma (C/EBP gamma; CEBPG) |
U20240 |
99 |
73 |
106 |
| cdc2-related protein kinase PISSLRE |
L33264 |
16 |
116 |
8 |
| cell cycle progression 2 protein (CPR2) |
O14710 |
107 |
79 |
96 |
| cell division protein kinase 4; cyclin-dependent kinase 4 (CDK4); PSK-J3 |
M14505 |
43 |
115 |
20 |
| cell division protein kinase 6 (CDK6); serine/threonine protein kinase PLSTIRE |
X66365 |
38 |
49 |
60 |
| cell division protein kinase 9 (CDK9); serine/threonine protein kinase PITALRE |
L25676 |
77 |
90 |
60 |
| chloride channel protein 4 (CLC-4) |
X77197 |
99 |
154 |
168 |
| clathrin assembly protein lymphoid myeloid leukemia (CALM) |
U45976 |
162 |
147 |
198 |
| clathrin coat assembly protein AP17; plasma membrane adaptor AP-2 17-kDa
protein; HA2 17-kDa subunit; clathrin assembly protein 2 small subunit |
X97074 |
98 |
81 |
125 |
| clathrin coat assembly protein AP47 homolog 2; Golgi adaptor AP-1 47-kDa
protein homolog 2; HA1 47-kDa subunit homolog 2; p47B |
D38293 |
138 |
97 |
141 |
| clathrin coat assembly protein AP50; plasma membrane adaptor AP-2 50-kDa
protein; HA2 50-kDa subunit; clathrin assembly protein 2 small subunit;
KIAA0109 |
D63475 |
113 |
91 |
153 |
| clathrin heavy subunit 1 (CLH-17); KIAA0034 |
D21260 |
180 |
100 |
176 |
| COFILIN |
X95404 |
108 |
54 |
106 |
| collagen 10 alpha 1 subunit (COL10A1); collagen alpha 1X subunit precursor |
X65120 |
135 |
108 |
141 |
| collagen 11 alpha 1 subunit precursor (COL11A1) |
P12107 |
82 |
98 |
64 |
| collagen 11 alpha 2 subunit (COL11A2) |
P13942; Q13273; Q07751 |
69 |
84 |
55 |
| collagen 16 alpha 1 subunit precursor (COL16A1) |
Q07092 |
99 |
126 |
77 |
| collagen 18 alpha 1 subunit (COL18A1) |
P39060 |
73 |
93 |
58 |
| collagen 4 alpha 2 subunit precursor (COL4A2) |
P08572 |
104 |
118 |
93 |
| collagen 4 alpha 3 subunit precursor (COL4A3) |
Q01955 |
107 |
115 |
93 |
| collagen 4 alpha 6 subunit precursor (COL4A6) |
Q14031 |
81 |
101 |
74 |
| collagen 6 alpha 1 subunit (COL6A1) |
Q14041 |
105 |
121 |
86 |
| collagen 6 alpha 2 subunit (COL6A2) |
Q13909; Q13911 |
98 |
128 |
85 |
| collagen 6 alpha 3 subunit (COL6A3) |
P12111 |
81 |
106 |
87 |
| collagen 8 alpha 1 subunit (COL8A1) |
P27658 |
77 |
103 |
79 |
| COLLAGEN ALPHA 1 (XV) CHAIN PRECURSOR |
L25286 |
94 |
99 |
96 |
| connective tissue growth factor precursor (CTGF) |
P29279 |
68 |
100 |
56 |
| connective tissue growth factor-like protein precursor (CTGFL); WISP2; CT58 |
AF074604 |
155 |
101 |
158 |
| corneodesmosin precursor (CDSN); S protein |
L20815 |
144 |
95 |
113 |
| cortactin; amplaxin; ems-1 oncogene |
M98343 |
143 |
107 |
137 |
| cullin homolog 2 (CUL2) |
Q13617 |
84 |
133 |
54 |
| cyclin G2 (CCNG2) |
Q16589 |
123 |
128 |
98 |
| cyclin H (CCNH); MO15-associated protein |
U11791; U12685 |
40 |
104 |
26 |
| cyclin I |
Q14094 |
436 |
84 |
87 |
| cyclin-dependent kinase 4 inhibitor D (CDKN2D); p19-INK4D |
U40343; U20498 |
70 |
92 |
55 |
| CYSTEINE-RICH PROTEIN 2 (CRP2) (ESP1 PROTEIN) |
D42123 |
227 |
229 |
234 |
| cytohesin-1; Sec7p-like protein |
Q15795 |
116 |
107 |
98 |
| delta catenin |
O00379 |
115 |
98 |
60 |
| delta-like protein precursor (DLK) |
U15979; Z12172 |
51 |
103 |
43 |
| desmin (DES) |
P17661; Q15787 |
160 |
109 |
104 |
| desmocollin 1A/1B precursor (DSC1); desmosomal glycoprotein 2/3 (DG2/DG3) |
Q08554 |
67 |
83 |
63 |
| desmocollin 2A/2B precursor (DSC2); desmosomal glycoprotein II/III |
Q02487 |
116 |
92 |
49 |
| desmocollin 3A/3B precursor (DSC3) + desmocollin 4 (DSC4) |
Q14574; Q14200 |
62 |
77 |
47 |
| desmoglein 1 precursor (DSG1); desmosomal glycoprotein 1 (DG1) |
Q02413 |
69 |
79 |
73 |
| desmoglein 2 precursor (DSG2); HDGC |
Q14126 |
75 |
89 |
47 |
| desmoplakin I & II (DSP; DPI & DPII) |
P15924 |
63 |
65 |
48 |
| diphosphomevalonate decarboxylase; mevalonate pyrophosphate decarboxylase
(MPD) |
U49260 |
136 |
74 |
132 |
| dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase
2; MAPKK 2); ERK activator kinase 2; MAPK/ERK kinase 2 (MEK2) |
P36507 |
88 |
125 |
92 |
| dual-specificity mitogen-activated protein kinase kinase 6 (MAP kinase kinase
6; MAPKK 6; MKK6); MAPK/ERK kinase 6; SAPKK3 |
P52564 |
69 |
102 |
43 |
| dual-specificity protein phosphatase 7; dual-specificity protein phosphatase
PYST2 |
X93921 |
135 |
61 |
168 |
| dual-specificty A-kinase anchoring protein 1 |
Q92667 |
63 |
62 |
107 |
| DXS6673E protein; X-linked mental retardation candidate gene |
X95808 |
144 |
95 |
153 |
| dynamin 2 |
L36983 |
138 |
87 |
148 |
| dystroglycan precursor; dystrophin-associated glycoprotein 1 (DAG1) |
L19711 |
141 |
87 |
143 |
| E2F dimerization partner 1; DRTF1-polypeptide 1 (DP1) |
L23959 |
50 |
171 |
27 |
| early growth response protein 1 (hEGR1); transcription factor ETR103; KROX24;
zinc finger protein 225; AT225 |
P18146 |
153 |
131 |
138 |
| elongation factor 2 (EF2) |
X51466 |
74 |
125 |
103 |
| Endothelial differentiation protein (edg-1) |
M31210 |
101 |
60 |
100 |
| ENDOTHELIAL PAS DOMAIN PROTEIN 1. EPAS1. |
U81984 |
139 |
109 |
157 |
| endothelial plasminogen activator inhibitor-1 precursor (PAI1; PLANH1) |
P05121 |
94 |
90 |
71 |
| endothelial tumor necrosis factor alpha-induced protein 1; B12 protein |
M80783 |
103 |
107 |
67 |
| endothelin 2 (ET2) |
P20800 |
64 |
67 |
43 |
| endothelin 3 (EDN3; ET3) |
J05081 |
74 |
80 |
62 |
| envoplakin (EVPL) |
Q92817 |
74 |
77 |
73.3 |
| ephrin type-A receptor 1 precursor; tyrosine-protein kinase receptor eph |
M18391 |
144 |
101 |
138 |
| ephrin type-A receptor 2 precursor; epithelial cell kinase (ECK); tyrosine-protein
kinase receptor ECK |
P29317 |
101 |
87 |
57 |
| ephrin type-A receptor 5 precursor; tyrosine-protein kinase receptor EHK1;
EPH homology kinase-1; HEK7 |
P54756 |
115 |
117 |
72 |
| ephrin type-B receptor 1 precursor; tyrosine-protein kinase receptor EPH-2;
NET |
P54762 |
147 |
103 |
107 |
| ephrin type-B receptor 2 precursor; tyrosine-protein kinase receptor EPH-3;
DRT; HEK; ERK |
L41939 |
50 |
69 |
50 |
| ephrin type-B receptor 4 precursor; tyrosine-protein kinase receptor HTK |
U07695 |
37 |
42 |
54 |
| ephrin-A5 precursor; EPH-related receptor tyrosine kinase ligand 7 (LERK-7);
AL-1 |
U26403 |
39 |
73 |
25 |
| ephrin-B1 precursor; eph-related receptor tyrosine kinase ligand 2 (LERK-2);
ELK ligand precursor (ELK-L) |
P98172 |
100 |
123 |
106 |
| ephrin-B2 precursor; EPH-related receptor tyrosine kinase ligand 5 (LERK-5);
HTK ligand (HTK-L) |
P52799 |
86 |
72 |
72 |
| ephrin-B3 precursor; eph-related receptor tyrosine kinase ligand 8 (LERK-8);
eph-related receptor transmembrane ligand ELK-L3 |
Q15768 |
60 |
75 |
55 |
| epidermal fatty acid-binding protein 5 (FABP5; EFABP); psoriasis-associated
fatty acid-binding protein homolog (PAFABP) |
M94856 |
139 |
112 |
237 |
| epidermal growth factor receptor (EGFR) |
P00533; P06268 |
103 |
102 |
70 |
| epidermal growth factor receptor kinase substrate EPS8 |
Q12929 |
86 |
141 |
71 |
| epidermal growth factor receptor substrate 15 (EPS15); AF-1P protein |
P42566 |
97 |
120 |
90 |
| erythroblastosis virus oncogene homolog 1 (ETS-1); p54 |
J04101 |
152 |
159 |
112 |
| ESE1, ERT, JEN, ELF3 (Epithelial-specific transcription factor) |
U73843 |
113 |
138 |
125 |
| EVI2B protein precursor; ectropic viral integration site 2B protein (EVI2B);
EVDB |
M60830 |
196 |
156 |
205 |
| extracellular signal-regulated kinase 1 (ERK1; p44-ERK1); microtubule-associated
protein 2 kinase; insulin-stimulated MAP2 kinase; MAP kinase 1 (MAPK1; p44-MAPK);
PRKM3 |
P27361 |
95 |
128 |
66 |
| extracellular signal-regulated kinase 4 (ERK4); MAP kinase 4 (MAPK4; p63-MAPK);
PRKM4 |
X59727 |
64 |
108 |
53 |
| extracellular signal-regulated kinase 5 (ERK5); BMK1 kinase |
Q13164; Q16634 |
94 |
111 |
100 |
| extracellular signal-regulated kinase 6 (ERK6); stress-activated protein
kinase-3; mitogen-activated protein kinase p38 gamma; (MAP kinase p38 gamma) |
P53778 |
180 |
103 |
112 |
| ezrin; cytovillin 2; villin 2 (VIL2) |
P15311; P23714 |
108 |
216 |
77 |
| fibrinogen A alpha polypeptide |
J00128 |
152 |
88 |
177 |
| fibrinogen B beta polypeptide |
J00129 |
124 |
87 |
140 |
| fibrinogen G gamma polypeptide |
X51473; X02415 K02569 |
103 |
84 |
110 |
| fibroblast growth factor 3 (FGF3) ; INT2 proto-oncogene protein precursor;
HBGF3 |
P45452 |
56 |
64 |
52 |
| fibroblast growth factor 5 precursor (FGF5); HBGF5 |
P12034 |
68 |
98 |
56 |
| fibroblast growth factor 6 precursor (FGF6); HBGF6; HST2 |
P10767 |
54 |
70 |
62 |
| fibroblast growth factor 8 (FGF8); androgen-induced growth factor precursor
(AIGF); HBGF8 |
P55075 |
64 |
73 |
69 |
| fibroblast growth factor receptor 3 precursor (FGFR3); JTK4 + fibroblast
growth factor receptor 2 precursor (FLG2) |
P22607 + Q99052 |
93 |
88 |
60 |
| fibroblast growth factor receptor 4 (FGFR4) |
L03840 |
57 |
72 |
52 |
| FIBROBLAST GROWTH FACTOR-10 |
AB002097 |
103 |
79 |
109 |
| FIBROBLAST GROWTH FACTOR-11 (FGF-11) (FIBROBLAST GROWTH FACTOR HOMOLOGOUS
FACTOR 3) (FHF-3) |
U66199 |
128 |
94 |
137 |
| FIBROBLAST GROWTH FACTOR-13 (FGF-13 ) (FIBROBLAST GROWTH FACTOR HOMOLOGOUS
FACTOR 2) (FHF-2) |
U66198 |
93 |
77 |
111 |
| FIBROBLAST GROWTH FACTOR-14 (FGF-14) (FIBROBLAST GROWTH FACTOR HOMOLOGOUS
FACTOR 4) (FHF-4) |
U66200 |
95 |
70 |
94 |
| fibronectin precursor (FN) |
P02751; Q14326 |
316 |
166 |
135 |
| fibronectin receptor alpha subunit (FNRA); integrin alpha 5 (ITGA5); VLA5;
CD49E antigen |
P08648 |
124 |
101 |
88 |
| ficolin 1 (FCN1) + FCN2; serum lectin p35 precursor |
D83920 + D49353 |
111 |
122 |
123 |
| focal adhesion kinase (FADK); proline-rich tyrosine kinase 2 (PYK2) |
Q05397 |
84 |
132 |
70 |
| focal adhesion kinase 2 (FADK2; FAK2); cell adhesion kinase beta (CAKbeta);
proline-rich tyrosine kinase 2 (PYK2) |
L49207 + U43522 + U33284 |
99 |
111 |
96 |
| FOLLISTATIN 1 AND 2 PRECURSOR (FS) (ACTIVIN-BINDING PROTEIN) |
M19481 |
114 |
72 |
127 |
| G protein-coupled receptor GPR-NGA |
U55312 |
54 |
106 |
30 |
| gamma-aminobutyric-acid receptor alpha-4 subunit precursor (GABA(A) receptor) |
U30461 |
102 |
81 |
132 |
| GAP JUNCTION BETA-2 PROTEIN (CONNEXIN 26) (CX26). |
M86849 |
211 |
125 |
221 |
| glycerol kinase |
L13943 |
194 |
117 |
170 |
| granulins precursor (GRN); acrogranin |
M75161 |
183 |
111 |
202 |
| growth factor receptor-bound protein 2 (GRB2) isoform; GRB3-3; SH2/SH3 adaptor
GRB2; ASH protein + epidermal growth factor receptor-bound protein 2 (EGFRBP-GRB2) |
L29511; M96995 |
126 |
250 |
93 |
| growth inhibitory factor; metallothionein-III (MT-III) |
P25713 |
194 |
298 |
130 |
| growth-arrest-specific protein (GAS) |
Q14393 |
96 |
64 |
62 |
| growth/differentiation factor 5 precursor (GDF5); cartilage-derived morphogenetic
protein 1 (CDMP1) |
U13660 |
100 |
68 |
115 |
| GTPase-activating protein (GAP); ras p21 protein activator; p120GAP; RASA |
M23379 |
204 |
191 |
160 |
| GUANINE NUCLEOTIDE-BINDING PROTEIN G(I), ALPHA-2 SUBUNIT (ADENYLATE CYCLASE-INHIBITING)(GNAI2) |
X04828 |
152 |
79 |
140 |
| GUANINE NUCLEOTIDE-BINDING PROTEIN G(Q), ALPHA SUBUNIT(GNAQ OR GAQ) |
U43083 |
182 |
92 |
148 |
| guanine nucleotide-binding protein G(Y) alpha 11 subunit (GNA11; GA11) |
M69013 |
244 |
101 |
169 |
| GUANINE NUCLEOTIDE-BINDING PROTEIN, ALPHA-15 SUBUNIT (ALPHA-16) |
M63904 |
195 |
113 |
178 |
| guanylate cyclase soluble alpha 2 subunit |
X63282; Z50053 |
205 |
119 |
199 |
| high mobility group protein (HMG-I) |
M23619 |
308 |
90 |
152 |
| high mobility group protein HMG2 |
P26583 |
86 |
86 |
83 |
| HIGH MOBILITY GROUP PROTEIN HMGI-C |
X92518 |
269 |
75 |
121 |
| homeobox protein HOX-A4; HOX-1D; HOX-1 4 |
M74297 |
122 |
150 |
151 |
| HOMEOBOX PROTEIN MOX-1 |
U10492 |
185 |
125 |
201 |
| host cell factor C1 (HCF); VP16 accessory protein; VCAF; CFF |
L20010 |
147 |
122 |
170 |
| hypothetical protein KIAA0056 |
D29954 |
100 |
70 |
134 |
| hypothetical protein KIAA0057 |
D38491 |
107 |
76 |
168 |
| I-rel (RELB) |
Q01201 |
84 |
98 |
86 |
| IkappaB epsilon (IKBE) |
O00221 |
99 |
106 |
125 |
| IkappaB kinase gamma subunit (IKK gamma) |
AF074382 |
141 |
89 |
143 |
| inhibitor of apoptosis protein 2 (HIAP2; IAP2) + IAP homolog B; TNFR2-TRAF
signalling complex protein 2; MIHB |
U45879 + U37547 |
74 |
121 |
108 |
| insulin-induced protein 1 |
U96876 |
75 |
126 |
92 |
| integrin alpha 1 (ITGA1); laminin & collagen receptor; VLA1; CD49A antigen |
P56199 |
137 |
111 |
103 |
| integrin alpha 3 (ITGA3); galactoprotein B3 (GAPB3); VLA3 alpha subunit;
CD49C antigen |
P26006 |
178 |
137 |
115 |
| integrin alpha 4 precursor (ITGA4); VLA4; CD49D antigen |
P13612 |
164 |
142 |
74 |
| integrin alpha 6 precursor (ITGA6); VLA6; CD49F antigen |
P23229; Q14646; Q16508; Q08443 |
112 |
247 |
62 |
| integrin alpha 7B precursor (IGA7B) |
Q13683 |
89 |
82 |
96 |
| integrin alpha 8 (ITGA8) |
P53708 |
92 |
98 |
71 |
| integrin alpha 9 (ITGA9); integrin alpha-RLC |
D25303; L24158 |
77 |
82 |
54 |
| integrin alpha E precursor (ITGAE); mucosal lymphocyte-1 antigen; hml-1
antigen; CD103 antigen |
P38570 |
112 |
101 |
99 |
| integrin beta 1 (ITGB1) |
Q13089; Q14647 |
170 |
106 |
79 |
| integrin beta 4 (ITGB4); CD104 antigen |
P16144 |
405 |
126 |
205 |
| integrin beta 5 subunit precursor (ITGB5) |
P18084 |
100 |
106 |
70 |
| integrin beta 6 precursor (ITGB6) |
P18564 |
152 |
127 |
73 |
| integrin beta 7 precursor (ITGB7) |
P26010 |
125 |
110 |
78 |
| integrin beta 8 precursor (ITGB8) |
P26012 |
282 |
302 |
72 |
| integrin-linked kinase (ILK) |
U40282 |
82 |
110 |
67 |
| intercellular adhesion molecule 3 precursor (ICAM3); CDW50 antigen; ICAM-R |
X69711; X69819 |
119 |
83 |
159 |
| INVOLUCRIN |
M13903 |
143 |
70 |
127 |
| jagged 1 (HJ1) |
AF028593 |
65 |
127 |
34 |
| jagged2 (JAG2) |
AF003521 |
73 |
133 |
34 |
| jun-B |
P17275 |
349 |
122 |
80 |
| junction plakoglobin (JUP); desmoplakin III (DP3) |
P14923 |
122 |
700 |
88 |
| keratinocyte growth factor (KGF); fibroblast growth factor 7 (FGF-7) |
P21781 |
76 |
71 |
60 |
| keratinocyte growth factor receptor (KGFR); fibroblast growth factor receptor
2 (FGFR2) + soluble KGFR + FGF-BEK; heparin-binding growth factor receptor
K-sam (HGFR K-sam) + secreted FGFR K-sam-III + secreted FGFR K-sam-IV |
Q14672 + P21802; Q12922 + P18443 + Q14718 + Q14719 |
93 |
81 |
74 |
| laminin 3-kDa receptor |
P08865 |
124 |
142 |
75 |
| laminin alpha 4 subunit precursor (laminin A4; LAMA4) |
Q16363; Q15335; Q14735 |
91 |
106 |
80 |
| laminin alpha-1 subunit precursor (LAMA1); laminin A chain |
X58531 |
143 |
106 |
163 |
| laminin alpha-2 subunit precursor (LAMA2); laminin M chain (LAMM); merosin
heavy chain |
Z26653 |
144 |
102 |
165 |
| laminin alpha-3 subunit precursor (LAMA3); epiligrin 170-kDa subunit (E170) |
L34155 |
96 |
98 |
111 |
| laminin beta 1 subunit precursor (laminin B1; LAMB1) |
P07942 |
92 |
138 |
74.4 |
| laminin beta 2 subunit precursor (laminin B2; LAMB2); S-laminin |
P55268; Q16321 |
86 |
119 |
77 |
| laminin beta-3 subunit precursor (LAMB3); laminin B1K chain; kalinin B1
chain |
L25541 |
94 |
109 |
103 |
| laminin gamma 1 subunit precursor (LAMC1); laminin B2 subunit (LAMB2) |
P11047 |
88 |
110 |
68 |
| leukemia-associated gene 1 |
O43261 |
344 |
105 |
89 |
| LGALS3, MAC2 (Galectin-3, MAC-2 antigen, IGE-binding protein, 35kD Lectin,
laminin-binding protein Lectin L-29, GALBP) |
M35368 |
154 |
99 |
203 |
| LHHCG-luteinizing hormone choriogonadrotropin receptor |
M63108 |
101 |
87 |
138 |
| LIM DOMAIN PROTEIN CLP-36 |
U90878 |
122 |
100 |
156 |
| LUCA2; lysosomal hyaluronidase 2 (HYAL2) ; PH-20 homolog |
U09577 |
188 |
110 |
112 |
| lysosomal protective protein precursor; cathepsin A; carboxypeptidase C;
PPGB |
M22960 |
82 |
60 |
81 |
| major prion protein precursor (PRP); PRP27-30; PRP33-35C; ASCR |
M13667 |
106 |
68 |
114 |
| MAPK/ERK kinase kinase 3 (MEK kinase 3; MEKK3) |
Q99759 |
98 |
112 |
69 |
| matrix metalloproteinase 1 (MMP1); interstitial collagenase precursor (CLG);
fibroblast collagenase |
P03956; P08156 |
76 |
81 |
48 |
| matrix metalloproteinase 10 (MMP10); stromelysin 2 precursor (STMY2; SL2);
transin 2 |
P09238 |
90 |
139 |
49 |
| matrix metalloproteinase 11 (MMP11); stromelysin 3 |
P24347 |
92 |
95 |
47 |
| matrix metalloproteinase 12 (MMP12); metalloelastase |
P39900 |
52 |
59 |
46 |
| matrix metalloproteinase 13 (MMP13); collagenase 3 precursor |
P45452 |
94 |
88 |
71 |
| matrix metalloproteinase 14 precursor (MMP14); membrane-type matrix metalloproteinase
1 (MT-MMP1); MMP-X1 |
P50281; Q92678 |
72 |
75 |
68 |
| matrix metalloproteinase 15 (MMP15); membrane-type matrix metalloproteinase
2 (MT-MMP2) |
P51511 |
43 |
55 |
47 |
| matrix metalloproteinase 16 precursor (MMP16); membrane-type matrix metalloproteinase
3 (MT-MMP3); MMP-X2 |
P51512 |
76 |
77 |
71 |
| matrix metalloproteinase 17 (MMP17); membrane-type matrix metalloproteinase
4 (MT-MMP4) |
Q14850 |
75 |
71 |
70 |
| matrix metalloproteinase 18 (MMP18) + MMP19 |
Q99580 + Q99542 |
93 |
118 |
46 |
| matrix metalloproteinase 2 (MMP2); 72-kDa gelatinase A; 72-kDa type IV collagenase
precursor (CLG4A); TBE-1 |
P08253 |
86 |
100 |
58 |
| matrix metalloproteinase 3 (MMP3); stromelysin 1 precursor (STMY1; SL1);
transin 1 |
P08254 |
95 |
101 |
65 |
| matrix metalloproteinase 7 (MMP7); matrilysin |
P09237 |
84 |
95 |
61 |
| matrix metalloproteinase 8 (MMP8); neutrophil collagenase precursor (CLG1);
PMNL collagenase (PMNL-CL) |
P22894 |
88 |
104 |
50 |
| matrix metalloproteinase 9 (MMP9); gelatinase B; 92-kDa type IV collagenase
precursor (CLG4B) |
P14780 |
94 |
92 |
63 |
| melanocyte protein PMEL 17 precursor; melanocyte lineage-specific antigen
GP100; melanoma-associated ME20 antigen; 95-kDa melanocyte-specific secreted
glycoprotein |
P40967 |
196 |
151 |
59 |
| melatonin receptor type 1B (MEL-1B-R) |
U25341 |
105 |
102 |
126 |
| menin |
O00255 |
85 |
87 |
74 |
| mesothelin precursor; CAK1 antigen |
U40434 |
49 |
46 |
98 |
| metabotropic glutamate receptor 4 precursor (GRM4; MGLUR4) |
X80818 |
107 |
81 |
122 |
| metalloprotease/disintegrin/cysteine-rich protein precursor (MDC9) |
Q13443 |
104 |
80 |
72 |
| metalloproteinase inhibitor 1 precursor (TIMP1); erythroid potentiating
activity (EPA); fibroblast collagenase inhibitor |
P01033; Q14252 |
84 |
95 |
61 |
| metalloproteinase inhibitor 3 precursor; tissue inhibitor of metalloproteinases
3 (TIMP3); mitogen-inducible gene 5 (MIG5) |
P35625 |
100 |
143 |
78 |
| metastasis-associated protein 1 (MTA1) |
U35113 |
42 |
799 |
28 |
| migration inhibitory factor-related protein 8 (MRP8); calgranulin A; leukocyte
L1 complex light subunit; S100 calcium-binding protein A8; cystic fibrosis
antigen (CFAG) |
X06234 |
150 |
98 |
112 |
| mitochondrial ATP synthase alpha chain precursor; ATP5A1 |
D14710 |
156 |
103 |
160 |
| moesin-ezrin-radixin-like protein (MERLIN); schwannomin (SCH); neurofibromatosis
2 (NF2) |
P35240 |
220 |
209 |
59 |
| MT1H (Methallothionein-IH, Metallothinein-0, MT-0) + Metallothionein isoform
1L (MT-1L) + Metallothionein isoform 1R + MT2 (Methallothionein-II) |
X64177 + X76717 + X97261 + X97260 |
133 |
256 |
258 |
| muscle cadherin precursor (M-cadherin); cadherin 14 or15 (CDH14 or CDH15) |
P55291 |
80 |
97 |
57 |
| mutL protein homolog; DNA mismatch repair protein MLH1; COCA2 |
P40692 |
99 |
100 |
80 |
| myelin-oligodendrocyte glycoprotein precursor (MOG) |
U18840 |
191 |
128 |
205 |
| N-acetylglucosamine-6-sulfatase precursor; glucosamine-6-sulfatase (G6S) |
Z12173; M23657 |
147 |
83 |
145 |
| N-sam; fibroblast growth factor receptor1 precursor (FGFR1); basic fibroblast
growth factor receptor precursor (bFGFR); fms-like tyrosine kinase-2 (FLT2)
+ heparin-binding growth factor receptor (HBGF-R-alpha-A1) + HBGF-R-alpha-A2
+ HBGF-R-alpha-A3 |
P11362; P17049 + Q02063 + Q02065 |
88 |
82 |
74 |
| NADH-cytochrome B5 reductase |
Y09501 |
145 |
87 |
151 |
| netrin-2 |
O00634 |
104 |
84 |
78 |
| neural cell adhesion molecule L1 precursor (N-CAM L1); MIC5 |
P32004 |
91 |
119 |
57 |
| neural cell adhesion molecule phosphatidylinositol-linked isoform precursor
(NCAM120); CD56 antigen |
P13591; P13592 |
82 |
105 |
62 |
| neural cell adhesion molecule; CALL |
O00533 |
104 |
330 |
66 |
| neural-cadherin precursor (N-cadherin; NCAD); cadherin 2 (CDH2) |
P19022; Q14923 |
68 |
89 |
56 |
| NIK serine/threonine protein kinase |
Y10256 |
87 |
115 |
100 |
| nm23-H4; nucleoside-diphosphate kinase; nucleoside 5'-diphosphate phosphotransferase
(NDK) |
Y07604 |
103 |
130 |
117 |
| notch2 |
U77493 |
55 |
152 |
29 |
| notch4; hnotch4 |
O00306 |
118 |
213 |
53 |
| nucleolar phosphoprotein B23; nucleophosmin (NPM); numatrin |
M23613 |
125 |
150 |
131 |
| oncostatin M-specific receptor beta subunit |
Q99650 |
101 |
90 |
72 |
| orphan receptor TR4 |
U10990 |
194 |
117 |
191 |
| p21-activated kinase alpha (PAK-alpha; PAK1) |
U24152 |
80 |
191 |
113 |
| patched homolog (PTC) |
Q13463 |
136 |
101 |
51 |
| paxillin |
P49023 |
146 |
109 |
86 |
| PDGF associated protein |
U41745 |
12 |
22 |
16 |
| phospholipase C beta 2 (PLC-beta 2; PLCB2); 1-phosphatidylinositol 4,5-bisphosphate
phosphodiesterase beta 2 |
M95678 |
202 |
112 |
198 |
| phospholipid transfer protein precursor (PTLP); lipid transfer protein II |
L26232 |
197 |
125 |
190 |
| plasma glutathione peroxidase precursor (GPXP; GPX3) |
D00632; X58295 |
177 |
144 |
202 |
| platelet membrane glycoprotein IIIA precursor (GP3A); integrin beta 3 (ITGB3);
CD61 antigen |
P05106; Q13413; Q16499 |
103 |
75 |
60 |
| platelet-derived growth factor (PDGF) receptor beta-like tumor suppressor
(PRLTS) |
D37965 |
128 |
89 |
126 |
| platelet-derived growth factor B subunit precursor (PDGFB; PDGF2); bacaplermin;
c-sis |
X02811; X02744; M12783; M16288 |
63 |
199 |
60 |
| platelet-derived growth factor receptor alpha subunit (PDGFRA); CD140A antigen |
P16234 |
203 |
103 |
72 |
| plexin-related protein (PLEXR) |
Q92472 |
69 |
86 |
63 |
| polycystin precursor; autosomal dominant polycystic kidney disease protein
1 |
U24497 |
44 |
123 |
70 |
| polypyrimidine tract-binding protein (PTB); heterogeneous nuclear ribonucleoprotein
I (HNRNP I); 57-kDa RNA-binding protein PPTB-1 |
X65372 |
91 |
153 |
129 |
| pre-B-cell leukemia transcription factor-1; homeobox protein pbx1; Homeobox
protein prl |
M86546 |
128 |
150 |
136 |
| procollagen 1 alpha 2 subunit precursor (COL1A2) |
X55525; J03464 |
90 |
118 |
85 |
| procollagen 2 alpha 1 subunit precursor (COL2A1) |
P02458 |
90 |
94 |
89 |
| procollagen 3 alpha 1 subunit precursor (COL3A1) |
P02461 |
97 |
110 |
87 |
| procollagen alpha 2(IV) subunit precursor |
X05562 |
149 |
161 |
75 |
| prohibitin (PHB) |
P35232 |
366 |
667 |
74 |
| proliferating cyclic nuclear antigen (PCNA); cyclin |
M15796; J04718 |
131 |
96 |
114 |
| protein serine/threonine kinase STK1; cell division protein kinase 7 (CDK7);
CDK-activating kinase (CAK); 39-kDa protein kinase |
L20320 |
77 |
47 |
48 |
| protein-tyrosine phosphatase MEG2 (PTPASE-MEG2) |
M83738 |
155 |
96 |
170 |
| protein-tyrosine phosphatase N precursor (R-PTP-N); PTP IA-2 |
L18983 |
93 |
65 |
102 |
| protocadherin 42 precursor (PCDH42); cadherin-like protein |
Q08174 |
81 |
64 |
49 |
| protocadherin 43 precursor (PCDH43); cadherin-like protein |
Q08192 |
82.2 |
61 |
52 |
| PRSM1 metallopeptidase |
Q15779 |
89 |
79 |
73 |
| purine-rich single-stranded DNA-binding protein alpha (PURA) |
M96684 |
136 |
102 |
137 |
| PUTATIVE RECEPTOR PROTEIN (PM1) |
X51804 |
149 |
88 |
148 |
| PUTATIVE SINGLE ZINC FINGER TRANSCRIPTION FACTOR PROTEIN |
AF039196 |
196 |
107 |
181 |
| RAR-related orphan receptor C |
U16997 |
192 |
116 |
200 |
| ras-related C3 botulinum toxin substrate 1; p21-rac1; ras-like protein TC25 |
M29870; M31467 |
102 |
571 |
45 |
| ras-related C3 botulinum toxin substrate 2; p21-rac2; small G protein |
M64595; M29871 |
117 |
862 |
60 |
| ras-related protein R-ras2; ras-like protein TC21; teratocarcinoma oncogene |
M31468 |
122 |
77 |
132 |
| ras-related protein RAB-11B; YPT3 |
X79780 |
117 |
71 |
130 |
| ras-related protein RAB-1A; YPT1-related protein |
M28209 |
129 |
74 |
147 |
| ras-related protein RAP-1A; C21KG; KREV-1 protein; GTP-binding protein SMG-p21A;
G-22K |
P10113 |
252 |
151 |
93 |
| receptor activation modifying protein 1 (RAMP1) |
AJ001014 |
309 |
110 |
185 |
| REGULATOR OF G-PROTEIN SIGNALING 7 (RGS7) (FRAGMENT) |
U32439 |
96 |
54 |
89 |
| retinoic acid receptor alpha |
X06614 |
133 |
78 |
124 |
| rho-related GTP-binding protein (RHOG); ARHG |
X61587 |
68 |
105 |
32 |
| S100 calcium-binding protein A7; psoriasin |
M86757 |
136 |
44 |
109 |
| SEC13-related protein (SEC13R) |
L09260 |
95 |
115 |
332 |
| serine kinase SRPK2 |
U88666 |
74 |
188 |
47 |
| serine/threonin protein phosphatase 2B catalytic subunit gamma; calmodulin-dependent
calcineurin A subunit gamma; testic-specific calcineurin catalytic subunit
(CAM-PRP catalytic subunit) |
S46622 |
63 |
80 |
44 |
| serine/threonine protein kinase |
Q12852 |
68 |
136 |
63 |
| serine/threonine protein kinase |
Q15524 |
68 |
115 |
52 |
| serine/threonine protein kinase KRS2 |
Q15802 |
76 |
128 |
58 |
| serine/threonine protein kinase minibrain homolog; HP86; DYRK |
D86550 |
64 |
205 |
33 |
| serine/threonine protein kinase PK428 |
U59305 |
62 |
98 |
58 |
| serine/threonine protein kinase PRP4 homolog |
Q13523 |
71 |
127 |
56 |
| serine/threonine protein kinase SAK |
Y13115 |
42 |
36 |
42 |
| serine/threonine protein phosphatase 2B catalytic subunit alpha isoform;
calmodulin-dependent calcineurin A subunit alpha isoform; CAM-PRP catalytic
subunit |
L14778 |
133 |
96 |
138 |
| serine/threonine protein phosphatase 2B catalytic subunit beta isoform;
calmodulin-dependent calcineurin A subunit beta isoform; CAM-PRP catalytic
subunit |
M29551 |
102 |
64 |
113 |
| serine/threonine protein phosphatase 5 (PP5); protein phosphatase T (PPT) |
X89416 |
97 |
80 |
120 |
| serine/threonine protein phosphatase 6 (PP6) |
X92972 |
46 |
47 |
45 |
| serine/threonine protein phosphatase PP-X |
X70218 |
96 |
74 |
126 |
| serine/threonine protein phosphatase PP1-alpha 1 catalytic subunit (PP-1A) |
M63960 |
116 |
132 |
204 |
| serine/threonine protein phosphatase PP2A-alpha catalytic subunit |
X12646 |
128 |
87 |
130 |
| serine/threonine-protein kinase KKIALRE |
X66358 |
22 |
107 |
31 |
| serine/threonine-protein kinase NEK2; NIMA-related protein kinase 2; NIMA-like
protein kinase 1; HSPK 21 |
P51955 |
69 |
136 |
71 |
| serine/threonine-protein kinase NEK3; NIMA-related protein kinase 3; HSPK
36 |
Z29067 |
56 |
88 |
34 |
| serine/threonine-protein kinase PCTAIRE 1 (PCTK1) |
Q00536 |
81 |
79 |
58 |
| serine/threonine-protein kinase PCTAIRE 2 (PCTK2) |
Q00537 |
80 |
205 |
51 |
| serine/threonine-protein kinase PCTAIRE 3 (PCTK3) |
Q07002 |
111 |
218 |
73 |
| serine/threonine-protein kinase PLK1 (STPK13) |
U01038 |
18 |
27 |
26 |
| serine/threonine-protein kinase receptor R3 precursor (SKR3); activin receptor-like
kinase 1 (ACVRL1; ALK1); TGF-beta superfamily receptor type I (TSR1) |
L17075 |
48 |
73 |
43 |
| serine/threonine-protein kinase receptor R4 precursor (SKR4); activin receptor-like
kinase 5 (ALK5); TGF-beta I receptor (TGFBR1) |
L11695 |
110 |
122 |
136 |
| sorcin 22-kDa protein (SRI); CP-22 |
L12387 |
107 |
70 |
113 |
| SOX-9 PROTEIN |
Z46629 |
138 |
84 |
150 |
| SPAM1, HYAL1, PH20 (Hyaluronidase, Sperm surface protein PH-20, Sperm adhesion
molecule 1) |
S67798 |
203 |
110 |
185 |
| syndecan 1 precursor (SYND1; SDC1); CD138 antigen |
J05392 |
220 |
102 |
189 |
| T-cell surface glycoprotein CD1D precursor; R3G1 |
J04142 |
112 |
84 |
125 |
| TAPASIN |
O15533 |
72 |
54 |
60 |
| tartrate-resistant acid phosphatase type 5 precursor (TR-AP); tartrate-resistant
acid ATPase (TRATPase); ACP5 |
J04430 |
201 |
117 |
195 |
| telomerase reverse transcriptase (hTRT) |
O14746 |
101 |
114 |
87 |
| tenascin precursor (TN); hexabrachion (HXB); cytotactin; neuronectin; GMEM;
miotendinous antigen; glioma-associated extracellular matrix antigen |
X78565; M55618 |
55 |
86 |
32 |
| tenascin-R |
Q92752 |
126 |
87 |
84 |
| tetranectin |
X64559 |
100 |
107 |
117 |
| thy-1 membrane glycoprotein precursor; CDW90 antigen |
M11749 |
131 |
143 |
177 |
| TIMP-2 (MI) |
P16035 |
99 |
78 |
80 |
| tissue factor pathway inhibitor 2 |
D29992 |
143 |
91 |
149 |
| tissue inhibtor of mettaloproteinase 4 (TIMP4) |
U76456 |
65 |
48 |
50 |
| transcription factor ETR101 |
M62831 |
170 |
105 |
124 |
| transforming protein rhoB; ARHB; ARH6 |
X06820 |
107 |
684 |
55 |
| tumor suppressor protein DCC precursor; colorectal cancer suppressor |
X76132 |
195 |
105 |
125 |
| type I cytoskeletal 10 keratin; cytokeratin 10 (K10) |
P13645 |
95 |
92 |
89 |
| type I cytoskeletal 12 keratin; cytokeratin 12 (K12) |
Q99456 |
141 |
97 |
99 |
| type I cytoskeletal 13 keratin; cytokeratin 13 (K13; CK13) + type I cytoskeletal
15 keratin; cytokeratin 15 (K15; CK15) + type I cytoskeletal 17 keratin;
cytokeratin 17 (K17; CK17) |
P13646 |
102 |
81 |
83 |
| type I cytoskeletal 14 keratin; cytokeratin 14 (K14; CK14) |
P02533 |
79 |
100 |
78 |
| type I cytoskeletal 16 keratin; cytokeratin 16 (K16; CK16); pseudo-keratin
K16 type I |
P30654 |
60 |
110 |
64 |
| type I cytoskeletal 18 keratin; cytokeratin 18 (K18) |
P05783 |
67 |
71 |
85 |
| type I cytoskeletal 19 keratin; cytokeratin 19 (K19; CK19) |
P08727 |
59 |
69 |
67 |
| type I cytoskeletal 9 keratin; cytokeratin 9 (K9; CK 9) |
P35527 |
81 |
95 |
79 |
| type II cytoskeletal 11 keratin (KRT11); cytokeratin 1 (K1; CK1); 67-kDa
cytokeratin; hair alpha protein |
P04264 |
69 |
83 |
73 |
| type II cytoskeletal 2 epidermal keratin (KRT2E); cytokeratin 2E (K2E; CK2E) |
P35908 |
88 |
84 |
82 |
| type II cytoskeletal 2 oral keratin; cytokeratin 2P (K2P; CK2P) |
Q01546 |
78 |
93 |
81 |
| type II cytoskeletal 4 keratin (KRT4); cytokeratin 4 (K4; CK4) |
P19013 |
96 |
109 |
86 |
| type II cytoskeletal 5 keratin (KRT5); cytokeratin 5 (K5; CK5); 58-kDa cytokeratin |
P13647 |
105 |
110 |
83 |
| type II cytoskeletal 6 keratin: cytokeratin 6A (CK6A); K6A keratin (KRT6A)
+ CK6B; KRT6B + CK6C; KRT6C + CK6D; KRT6D + CK6E; KRT6E + CK6F; KRT6F |
P02538 |
80 |
77 |
92 |
| type II cytoskeletal 7 keratin (KRT7); cytokeratin 7 (K7; CK7) |
P08729 |
78 |
89 |
76 |
| type II cytoskeletal 8 keratin (KRT8); cytokeratin 8 (K8; CK8) |
P05787; Q14716; Q14717; Q14099 |
114 |
108 |
90 |
| tyrosine-protein kinase receptor tyro3 precursor; rse; sky; dtk |
D17517 |
191 |
102 |
150 |
| vascular endothelial growth factor B precursor (VEGFB) + VEGF-related factor
isoform VRF186 |
U48801; U43369 |
47 |
119 |
50 |
| vascular endothelial growth factor C precursor (VEGF-C); vascular endothelial
growth factor related protein (VRP); FLT4 ligand |
P49767 |
76 |
57 |
57 |
| vascular endothelial growth factor precursor (VEGF); vascular permeability
factor (VPF) |
M32977; M27281 |
52 |
89 |
45 |
| vascular endothelial growth factor receptor 1 (VEGFR1); tyrosine-protein
kinase receptor flt + soluble VEGFR; tyrosine-protein kinase receptor SFLT |
P17948; P16057 + Q12954 |
269 |
151 |
76 |
| vascular endothelial growth factor receptor 2 precursor (VEGFR2); kinase
insert domain receptor (KDR); FLK1 |
P35968; Q14178 |
68 |
75 |
79 |
| vascular endothelial growth factor receptor 3 precursor (VEGFR3); tyrosine-protein
kinase receptor FLT4 |
P35916 |
153 |
116 |
63 |
| vesicle-membrane fusion protein SNAP23A |
Y09567 |
127 |
120 |
299 |
| vimentin (VIM) |
P08670 |
388 |
172 |
141 |
| vitronectin precursor (VTN); serum spreading factor; S-protein |
P04004; P01141 |
109 |
111 |
91 |
| vitronectin receptor alpha subunit (VNRA); integrin alpha 5 subunit (ITGA5);
CD51 antigen |
M14648; J02826; M18365 |
147 |
95 |
109 |
| voltage-dependent anion-selective channel protein 1 (VDAC1); plasmalemmal
porin; outer mitochondrial membrane protein porin; porin 31HL; porin 31HM |
L06132 |
136 |
113 |
140 |
| voltage-gated potassium channel protein KV12; HUKIV; HBK5; RBK2; NGK1 |
L02752 |
100 |
64 |
109 |
